Journal of Neuroscience
Articles in this Issue
<i>Klf5</i> regulates the transition from apical radial glia to intermediate progenitor cells in the developing mammalian brain
Krüppel-like factors (Klfs) are DNA-binding transcriptional factors that regulate multiple physiological features, including the cell cycle, cell differentiation, and tissue organization. Among them,...
Hierarchical afferent connectivity drives population-wide bursting dynamics in a computational model of human-derived excitatory neuronal networks
This work presents a computational model of excitatory neuronal networks derived from human-induced pluripotent stem cells (hiPSCs), whose activity was recorded with Micro-Electrode Arrays (MEAs). A k...
Substantia nigra pars reticulata regulates prefrontal cortex via ventromedial thalamus
The ventromedial thalamus (VM) innervates layer 1 (L1) of the medial prefrontal cortex (mPFC) to influence executive function and arousal. Thalamocortical (TC) cells in VM process inputs from cortex t...
Phase-locking saccades to posterior alpha oscillations improves the neural representation of visual objects during memory formation
Visual memory formation relies on the intake and neural processing of discrete samples provided by gaze fixations and saccades. Past research has highlighted a functional relationship between the timi...
Repeated Viewing of a Film Clip Changes Event Timescales in The Brain
Many everyday experiences share a recurring structure: routines, familiar routes, rewatched films, and replayed songs. How do repeated encounters with such structure alter the brain’s representations...
A dorsal versus ventral network for understanding others in the developing brain
Young children strongly depend on others, and learning to understand their mental states (referred to as Theory of Mind, ToM) is a key challenge of early cognitive development. Traditionally, ToM is t...
Alzheimer’s pathology enhances excitatory synaptic input and integration in VTA dopamine neurons
In Alzheimer’s disease (AD) models, ventral tegmental area (VTA) dopamine neurons are intrinsically hyperexcitable, yet release less dopamine and exhibit dysfunctional downstream signaling. Synaptic t...