Journal of Neuroscience
Articles in this Issue
Erratum: Shults et al., “Neurological and Neurodegenerative Alterations in a Transgenic Mouse Model Expressing Human α-Synuclein under Oligodendrocyte Promoter: Implications for Multiple System Atrophy”
Pharmacological and Genetic Approaches to Downregulate FIS1 Mitigate Neuropathic Pain
Despite the established link between neuropathic pain and abnormal mitochondrial fission in neurons, the specific role of mitochondrial fission protein 1 (FIS1) in this process remains to be fully elu...
First Application of a Novel Brain Template: Motor Training Improves Cortico-cerebellar Connectivity in Cerebellar Ataxia
People with cerebellar degeneration show characteristic ataxic motor impairments. Despite cerebellar dysfunction, they can improve motor performance through sensorimotor training. Yet, how such traini...
Global Motor System Suppression as the Primary Mechanism of Human Action Stopping: Challenging the Pause-Then-Cancel Model
The ability to stop a planned or ongoing action is fundamental to inhibitory control. A recent theory proposes that stopping involves two distinct phases: an initial global suppression of motor activi...
Circuit Reconstruction after Traumatic Spinal Cord Injury by Cellular and Pharmacological Approaches
Extensive neuronal loss, progressive neurodegeneration, and circuit impairment are the key pathological features of spinal cord injury (SCI). The intrinsic capacity of the injured spinal cord to reple...
Impaired Online and Enhanced Offline Motor Sequence Learning in Individuals with Parkinson's Disease
Whereas memory consolidation research has traditionally focused on longer temporal windows (i.e., hours to days) following an initial learning episode, recent research has also examined the functional...
Phase Consistency Dynamics of Memory Encoding
Human and animal studies implicate theta and alpha oscillations in memory function. We tested whether theta, alpha, and beta phase consistency predicts memory encoding dynamics in neurosurgical patien...
The Orbitofrontal Cortex Underlies Consolidation of Pavlovian Anticipatory Arousal Responses in Macaque Monkeys
Altered arousal is characteristic of many mental health disorders, including major depressive disorder (MDD). Several studies link neural activity in the orbitofrontal cortex (OFC) with anticipation o...
TMS-Based Neurofeedback Training of Mental Finger Individuation Induces Neuroplastic Changes in the Sensorimotor System
Neurofeedback (NF) training based on motor imagery is increasingly used in neurorehabilitation with the aim to improve motor functions. However, the neuroplastic changes underpinning these improvement...
Cholinergic Waves Have a Modest Influence on the Transcriptome of Retinal Ganglion Cells
In the early stages of development, correlated activity known as retinal waves causes periodic depolarizations of retinal ganglion cells (RGCs). The β2KO mouse, which lacks the β2 subunit of the nicot...
Striatal Gradient in Value-Decay Explains Regional Differences in Dopamine Patterns and Reinforcement Learning Computations
Dopamine has been suggested to encode reward-prediction-error (RPE) in reinforcement learning (RL) theory but also shown to exhibit heterogeneous patterns depending on regions and conditions: some exh...