Journal of Neuroscience
Articles in this Issue
Neuroscience for All: Sharing Neuroscience with Your Community
Science communication plays an essential role in bridging the gap between researchers and the general public. Now, more than ever, it is essential for neuroscientists to interact with their communitie...
Theta Oscillations as a Bridge between Perception and Memory
Expectation Modulates Hedonic Experiences and Midbrain Responses to Sweet Flavor
Non-nutritive sweeteners are sugar substitutes that may promote weight management by reducing an individual's calorie intake. It is, however, unclear whether (1) sugar and non-nutritive sweetener elic...
Flexible Coupling of Synaptic and Intrinsic Plasticity in a Cerebellar Circuit
It is increasingly recognized that learning and memory depend not only on changes in synaptic strength but also on experience-dependent modifications of intrinsic neuronal excitability. However, how t...
β-Bursting as a Sensitive Neural Marker of Inhibitory Control in Healthy Older Adults: A Linear Mixed-Effects Modeling and Threshold-Free Cluster Approach
Inhibitory control is essential for adaptive behavior and declines with age, yet the underlying neural dynamics remain poorly understood. The β-rhythm (15–29 Hz) is associated with inhibitory signalin...
Punishments Enhance Reward Learning by Modulating Striatal Prediction Errors
People often make decisions in contexts where rewards and punishments co-occur, yet most human research still examines reward and punishment learning as independent processes. Here, across three studi...
Microglia Modulate Information Processing in the Mouse Barrel Cortex
Microglia, the main immune cells of the central nervous system, are crucial for maintaining brain homeostasis by modulating immune processes and neurovascular function. However, the mechanisms by whic...
Spinal Processing of Spatiotemporally Diverse Tactile Stimuli: Computational Insights into Allodynia and Spinal Cord Stimulation
Weakening of synaptic inhibition in the spinal dorsal horn (SDH) contributes to mechanical allodynia after peripheral nerve pathology. Restoring inhibition can alleviate allodynia, whereas weakening i...
The Tuned Cortex: Convergent Expertise-Related Structural and Functional Remodeling across the Adult Lifespan
Neuroplasticity is a defining property of the brain. Structural and functional brain changes arise soon after learning and are particularly evident following years of practice that underpin expert per...
Edinger-Westphal Neurons Contribute to Emergence from Desflurane and Sevoflurane Anesthesia in Mice
Most general anesthetics have long been believed to work by exerting a wide range of inhibitory impacts on the central nervous system, yet accumulating evidence has highlighted their excitatory effect...
Effects of Expectation, Attention, and NMDA Receptor Blockade on Feedforward and Feedback Processing
Perception is increasingly viewed as an inferential process wherein sensory inputs are integrated with prior expectations. We employed time-resolved decoding on electroencephalography (EEG) data (...
Cochlear Amplification Modulates Synaptic Transmission at the Endbulb of Held Synapse in the Cochlear Nucleus
In the mammalian cochlea upon acoustic stimulation, outer hair cells (OHCs) push and pull the basilar membrane, amplifying its vibration and therefore expanding the dynamic range of hearing. As a resu...
Hemodynamic and Electrophysiological Progression of the Rose Bengal Photothrombotic Stroke Model in Mice
The photothrombotic stroke model is gaining popularity due to its relative simplicity, minimal invasiveness, and clinical relevance. Photothrombosis involves the delivery of an intravascular photosens...
Comparing the Limbic–Frontal Connectome across the Primate Order: Conservation of Connections and Implications for Translational Neuroscience
The interaction of the limbic system and frontal cortex of the primate brain is important in many affective behaviors. For this reason, it is heavily implicated in a number of psychiatric conditions....