Journal of Neuroscience
Articles in this Issue
Evaluating TRIM46's Role in Axon Initial Segment Formation
Nicotine Withdrawal Drives Aversive Behaviors by Recruiting Inhibitory Interpeduncular Nucleus Inputs to the Laterodorsal Tegmentum in Mice
Nicotine addiction remains a major cause of disease and premature death worldwide. Nicotine modulates neural pathways that underlie both rewarding and aversive behavioral effects, but persistent activ...
Neural Synchrony and Consumer Behavior: Predicting Friends’ Behavior in Real-World Social Networks
The endogenous aspect of social influence, reflected in the spontaneous alignment of behaviors within close social relationships, plays a crucial role in understanding human social behavior. In two st...
CaMKIIβ-mediated Phosphorylation Enhances Protein Stability of Spastin to Promote Neurite Outgrowth
Neurite outgrowth is critically controlled by calcium influx-mediated cytoskeleton dynamics. Spastin, a AAA ATPase microtubule-severing protein, also plays an important role in neurite outgrowth. Howe...
The Somatosensory Cortex and Body Representation: Updating the Motor System during a Visuoproprioceptive Cue Conflict
The brain's representation of hand position is critical for voluntary movement. Representation is multisensory, combining visual and proprioceptive cues. When these cues conflict, the brain recalibrat...
Strategies to Decipher Neuron Identity from Extracellular Recordings in Behaving Nonhuman Primates
Identification of the neuron type is critical when using extracellular recordings in awake, behaving animal subjects to understand computation in neural circuits. Yet, modern recording probes have lim...
Interference of Mid-level Speech and Noise Statistics Underlies Human Speech Recognition Sensitivity in Natural Environmental Noise
Recognizing speech in noise, such as in a busy restaurant, is an essential cognitive skill where the task difficulty varies across environments and noise levels. Although there is growing evidence tha...
Sleep State Influences Early Sound Encoding at Cortical But Not Subcortical Levels
In sleep, the brain balances protecting processes like memory consolidation with preserving responsiveness to significant external stimuli. Although reductions in higher-level auditory processes durin...
Stress-Responsive Neuronal Ensembles and β-Adrenergic Signaling in the Basolateral Amygdala Modulate the Infralimbic Cortical Activity and Govern the Delayed Stress-Induced Fear Extinction Deficit
Stress is a critical risk factor for the development of psychological disorders, including anxiety and post-traumatic stress disorder. Key brain regions, including the basolateral amygdala (BLA) and t...
The Trembling Hand Unraveled: Motor Dynamics and Choice Inconsistency
Extensive evidence shows that humans are inconsistent in their choices. Yet, the neural mechanism underlying inconsistent choice remains unknown. Here, we aim to show that inconsistent choice is tied...
Age-Related Increase in Locus Ceruleus Activity and Connectivity with the Prefrontal Cortex during Ambiguity Processing
Interpreting ambiguous environmental cues, like facial expressions, becomes increasingly challenging with age, especially as cognitive resources decline. Managing these challenges requires adaptive ne...