Journal of Neuroscience
Articles in this Issue
Methylphenidate Promotes a Frontoparietal-Dominant Brain State Improving Cognitive Performance: A Randomized Trial
Methylphenidate (MP) is a widely used stimulant medication for the treatment of attention-deficit hyperactivity disorder that enhances brain dopamine signaling and improves attention. However, how dop...
Striatal Dopamine Represents Valence on Dynamic Regional Scales
Adaptive decision-making relies on flexible updating of learned associations where environmental cues come to predict valenced stimuli, such as food or threat. Cue-guided behavior depends on a network...
Concentration-Dependent Bidirectional Modification of Evoked Synaptic Transmission by Gadolinium and Adverse Effects of Gadolinium-Based Contrast Agent
Gadolinium-based contrast agents (GBCAs) for magnetic resonance imaging (MRI) are gadolinium chelates and can leave gadolinium in brain regions after administration, causing damage to brain tissues. H...
Feedback Scales the Spatial Tuning of Cortical Responses during Both Visual Working Memory and Long-Term Memory
Perception, working memory, and long-term memory each evoke neural responses in the visual cortex. While previous neuroimaging research on the role of the visual cortex in memory has largely emphasize...
Esrp1 and Esrp2 Regulate the Stability of <i>tmc1</i> / <i>2a</i> mRNAs in Zebrafish Sensory Hair Cells
RNA-binding proteins (RBPs) are important for posttranscriptional RNA processing, including pre-mRNA alternative splicing, mRNA stability, and translation. Several RBPs have been shown to play pivotal...
CART Neurons in the Hypothalamic Ventral Premammillary Nucleus (PMv) in Rats Mediate Maternal, But Not Inter-male Aggression
Compared to males, aggression is less frequently noticed in females. Fierce maternal-aggression to thwart the attack/threat of a male conspecific/intruder is transiently expressed as she defends her p...
Visuomotor Memory Is Not Bound to Visual Motion
The motor system adapts its output in response to experienced errors to maintain effective movement in a dynamic environment. This learning is thought to utilize sensory prediction errors, the discrep...
Motor Preparation Tracks Decision Boundary Crossing Rather Than Accumulated Evidence in Temporal Decision-Making
Interval timing, the ability of animals to estimate the passage of time, is thought to involve diverse neural processes rather than a single central “clock” (Paton and Buonomano, 2018). Each of the di...
Decoding the Neural Dynamics of Headed Syntactic Structure Building
The brain builds hierarchical phrases during language comprehension; however, the details and dynamics of the phrase-building process remain underspecified. This study directly probes whether the neur...
Visual Statistical Learning Alters Low-Dimensional Cortical Architecture
Our brains are in a constant state of generating predictions, implicitly extracting environmental regularities to support later cognition and behavior, a process known as statistical learning (SL). Wh...
Novel Verbal Instructions Recruit Abstract Neural Patterns of Time-Variable Information Dimensionality
Human performance is endowed by neural representations of information that is relevant for behavior, some of which are also activated in a preparatory fashion to optimize later execution. Most studies...
Toward a Mechanistic Understanding of Reading Difficulties: Deviant Audiovisual Learning Dynamics and Network Connectivity in Children with Poor Reading Skills
Mastering the associations between letters and their corresponding speech sounds (LSS) is pivotal in the early stages of reading development, requiring an effective reorganization of brain networks. C...
Association of Bidirectional Network Cores in the Brain with Perceptual Awareness and Cognition
The brain comprises a complex network of interacting regions. To understand the roles and mechanisms of this intricate network, it is crucial to elucidate its structural features related to cognitive...
Reducing Tinnitus via Inhibitory Influence of the Sensorimotor System on Auditory Cortical Activity
Tinnitus is the subjective perception of a sound without corresponding external acoustic stimuli. Research highlights the influence of the sensorimotor system on tinnitus perception. Associated neuron...
A Hippocampal–Parietal Network for Reference Frame Coordination
Navigating space and forming memories based on spatial experience are crucial for survival, including storing memories in an allocentric (map-like) framework and conversion into egocentric (body-cente...