Journal of Neuroscience
Articles in this Issue
Bidirectional Modulation of Beam Traversal Performance by Acetylcholine in the Cerebellar Nuclei
The cerebellum plays a key role in coordinating balance and movement control. Most studies of cerebellar function focus on the role of cerebellar glutamatergic inputs; thus, the roles of neuromodulato...
Neuronal Activity Suppresses NEUROD-Dependent Transcription and Genome Organization
Neuronal activity induces gene expression programs associated with plasticity in the brain, but it also transiently suppresses gene expression through poorly understood mechanisms. Here, we report tha...
Contributions from Long-Term Memory Explain Superior Visual Working Memory Performance with Meaningful Objects
Working memory (WM) capacity has been claimed to be larger for meaningful objects than for simple features, possibly because richer semantic representations enhance item distinctiveness. However, prio...
Altered Structural Plasticity Mediated by mGlu and NMDA Receptors and Impaired Cognition in a Genetic ASD Model (Shank3 <sup>+/−</sup> Mice)
Dendritic spine morphology is strongly associated with neurodevelopmental disorders. Synaptic plasticity alters spine volume, a phenomenon known as structural plasticity, which influences information...
Neuronal Features of Visual Attention in the Mouse Superior Colliculus Depend on Learned Behavioral Relevance
Visual selective attention is not wired into the brain fully formed and immutable but is acquired and refined as animals learn by interacting with their environment. Here we investigated this process...
The Spatial Coding of Touch Is Defined in Intrinsic, Limb-Specific Coordinates: An EEG Study
The brain computes the spatiotopic position of touch by integrating tactile and proprioceptive signals (i.e., tactile remapping). While it is often assumed that the spatiotopic touch location is mappe...
Distinct Mechanisms for Panoramic and Landmark-Based View Integration in Human Place-Selective Cortex
To encode a cognitive map of an environment, a navigator must be able to integrate across perceptual views corresponding to the same place. This can be done in two ways: first, by integrating across t...
Hidden State Inference or Continuous Belief Updating during a Dynamic Visuomotor Skill
Adaptive sensorimotor behavior requires individuals to flexibly update their beliefs in response to changes in environmental context. Theories of predictive processing propose that such flexibility ar...
Quantifying State-Dependent Control Properties of Brain Dynamics from Perturbation Responses
The brain can be conceptualized as a control system facilitating transitions between states, such as from rest to motor activity. Applying network control theory to measurements of brain signals enabl...
Neurochemical and Neurophysiological Effects of Intravenous Administration of <i>N,N</i> -Dimethyltryptamine in Rats
N , N -Dimethyltryptamine (DMT) is a serotonergic psychedelic that is being investigated for the treatment of psychiatric disorders. Althoug...
The Anterior Temporal Semantic Hub in the Left and Right Hemispheres: A Unitary System or Two Separate Systems for Meaning?
Research indicates that the anterior temporal lobes (ATLs) in the left and right hemispheres constitute a supramodal hub for verbal and nonverbal semantic information. However, it remains unclear whet...
Caudal Granular Insular Cortex to Somatosensory Cortex I: A Critical Pathway for the Transition of Acute to Chronic Pain
Allodynia (perceiving touch as painful) is an enduring symptom of neuropathic pain. While acute pain is initiated by afferent signaling from the periphery to spinal cord, pain chronification recruits...
Recovery of Retinal Terminal Fields after Traumatic Brain Injury: Evidence of Collateral Sprouting and Sexual Dimorphism
The central nervous system is characterized by its limited regenerative potential, yet striking examples of functional recovery after injury in animal models and humans highlight its capacity for repa...
Local Neuronal Ensembles That Coreactivate across Regions during Sleep Are Preferentially Stabilized
Neuronal ensembles, which represent coordinated activity patterns within individual brain regions, play crucial roles in memory. While local ensembles dynamically change in response to experience, fac...