Journal of Neuroscience
Articles in this Issue
A Neural Compass in the Human Brain during Naturalistic Virtual Navigation
A central component of wayfinding is the ability to maintain a consistent representation of one's facing direction (FD) when moving about the world. In rodents, head direction cells are believed to su...
Increased Sleep Spindles in Regions Engaged during Motor Learning Predict Memory Consolidation
Sleep spindles play a critical role in sleep-dependent memory consolidation. Although spindles can occur widely across the cortex, they are often focal. Focal spindles may promote plasticity in distin...
SRC Kinase Isoforms Regulate mRNA Splicing during Neural Development
Alternative mRNA splicing generates transcriptomic diversity to direct tissue-specific functions. There is a high level of alternative splicing in the brain during embryonic development, but the maste...
F-BAR Proteins CIP4 and FBP17 Function in Cortical Neuron Radial Migration and Process Outgrowth
Neurite initiation from newly born neurons is a critical step in neuronal differentiation and migration. Neuronal migration in the developing cortex is accompanied by dynamic extension and retraction...
Ciliary ARL13B Is Essential for Vision and Morphogenesis of Cone Outer Segments
Mutations in ARL13B lead to Joubert syndrome, a ciliopathy with neurological and retinal abnormalities. In photoreceptors, ARL13B localizes to the connecting cilia and outer segments. However, the spe...
Isolating Brain Mechanisms of Expectancy Effects on Pain: Cue-Based Stimulus Expectancies versus Placebo-Based Treatment Expectancies
Clinical trials, laboratory experiments, and neuroimaging studies provide converging evidence that pain is highly sensitive to expectations, whether based on the psychosocial context surrounding treat...
Locally Induced Traveling Waves Generate Globally Observable Traveling Waves
Cortical traveling waves have been proposed as a fundamental mechanism for neural communication and computation. Methodological uncertainties currently limit the interpretability of noninvasive, extra...
Disrupted Neurogenesis from Basal Intermediate Precursor Cells Alters the Postnatal Neocortex in the TcMAC21 Mouse Model of Down Syndrome
Cognitive, social behavior, speech, and motor skills are known challenges for people with trisomy 21/Down syndrome (DS), but the precise mechanisms that lead to these impactful changes have not yet be...
Cell Type-Dependent Short-Term Plasticity and Dopaminergic Modulation of Sensory Synapses onto Mouse Superficial Dorsal Horn Neurons
While transient changes in synaptic strength occurring during the repetitive firing of primary afferent inputs to the spinal superficial dorsal horn (SDH) are predicted to strongly influence the fidel...
Neural Sensitivity to Radial Frequency Patterns in the Visual Cortex of Developing Macaques
Visual resolution, contrast sensitivity, and form perception improve gradually with age. In nonhuman primates, the sensitivity and resolution of cells in the retina, lateral geniculate nucleus, and pr...