Journal of Neuroscience
Articles in this Issue
Computational Properties of the Prefrontal Cortex
Prefrontal Network Mechanisms of Psychiatric Deep Brain Stimulation
Deep brain stimulation (DBS) is an emerging treatment for otherwise treatment-refractory psychiatric disorders. It can produce remarkable clinical results in expert hands, but has not fared as well in...
Erratum: Pena et al., “Novel Verbal Instructions Recruit Abstract Neural Patterns of Time-Variable Information Dimensionality”
ACC Reward Location Information Is Carried by Hippocampal Theta Synchrony and Suppressed in a Type 2 Diabetes Model
The anterior cingulate cortex (ACC) is important for higher-order cognitive functions, emotional responses, and monitoring internal states. ACC dysfunction has been implicated in an array of psychiatr...
Retinoid-X-Receptor as a Mediator of Poststroke Recovery by Reversing Age-Associated Phenotypes of Microglia/Hematogenous Macrophages
After stroke, microglia and hematogenous macrophages, together referred to as MΦ, clear dead cells and cellular debris in the infarcted brain through phagocytosis as an essential part of the recovery...
Spatiotemporal Patterns in Cortical Development: Age, Puberty, and Individual Variability from 9 to 13 Years of Age
Human and nonhuman primate studies suggest that timing and tempo of cortical development varies neuroanatomically along a sensorimotor-to-association (S–A) axis. Prior human studies have reported a pr...
Ventral Tegmental Area Dopamine Neural Activity Switches Simultaneously with Rule Representations in the Medial Prefrontal Cortex and Hippocampus
Multiple brain regions need to coordinate activity to support cognitive flexibility and behavioral adaptation. Neural activity in both the hippocampus (HPC) and medial prefrontal cortex (mPFC) is know...
Organization of Brainwide Inputs to Discrete Lateral Septum Projection Populations
The lateral septum (LS) is anatomically positioned to play a critical role in directing information from the hippocampus and cortex to downstream subcortical structures, such as the hypothalamus. Earl...
Prediction Error-Related Memory Enhancement Depends on the Neural State Surrounding the Prediction Error Event
Prediction errors (PEs) can enhance memory for preceding events. While such PE-related memory enhancements are critical for understanding adaptive memory, their underlying mechanisms are not fully und...
High Beta Power in the Ventrolateral Prefrontal Cortex Indexes Human Approach Behavior: A Case Study
Deep brain stimulation (DBS) of the ventral capsule and ventral striatum (VC/VS) is an effective therapy for treatment-resistant obsessive–compulsive disorder (trOCD). DBS initiation often produces ac...
Orbitofrontal-Hippocampal State Coding Dynamics during Reversal Learning
To build an understanding of our world, we make inferences about the connections between our actions, experiences, and the environment. This process, state inference, requires an agent to guess the cu...
Robustness of Working Memory to Prefrontal Cortex Microstimulation
Delay period activity in the dorsolateral prefrontal cortex (dlPFC) has been linked to the maintenance and control of sensory information in working memory. The stability of working memory-related sig...