Journal of Neuroscience
Articles in this Issue
Mef2c Controls Postnatal Callosal Axon Targeting by Regulating Sensitivity to Ephrin Repulsion
Intracortical circuits, including long-range callosal projections, are crucial for information processing. The development of neuronal connectivity in the cerebral cortex is contingent on ordered emer...
Impact of Rod-Dominant Mesopic Conditions on Spatial Summation and Surround Suppression in Early Visual Cortex
Mesopic (dim light) conditions are prevalent in everyday environments, yet most human vision research is conducted under idealized, photopic (bright) conditions. Electrophysiological studies suggest t...
Functional Heterogeneity within the Primate Ventral Striatum for Motivational Regulation
The ventral striatum (VS) is a key brain region for reward processing and motivation, and its dysfunctions have been implicated in psychiatric disorders such as apathy and obsessive–compulsive disorde...
Mitochondrial Glutamine Metabolism Drives Epileptogenesis in Primary Hippocampal Neurons
All available antiseizure medications aim at symptomatic control of epilepsy, but there is no strategy to stop the development of the disease. The main reason is the lack of understanding of the epile...
Timing of Speech in Brain and Glottis and the Feedback Delay Problem in Motor Control
To learn complex motor skills, an organism must be able to assign sensory feedback events to the actions that caused them. This matching problem would be simple if motor neuron output led to sensory f...
Joint Heritability of Sleep EEG Spindle Activity and Thalamic Volume in Early Adolescence
Sleep spindles, transient bursts of rhythmic activity during non-rapid eye movement sleep, are generated by the thalamocortical network through an intricate interplay between the thalamus and the cort...
Multimodal Correspondence between Optogenetic fMRI, Electrophysiology, and Anatomical Maps of the Secondary Somatosensory Cortex in Nonhuman Primates
Optogenetic neuromodulation combined with functional MRI (opto-fMRI) enables noninvasive monitoring of brain-wide activity and probes causal connections. In this study, we focused on the secondary som...
Optogenetic Stimulation of Novel Tph2-Cre Rats Advances Insight into Serotonin's Role in Locomotion, Reinforcement, and Compulsivity
Serotonin critically modulates the activity of many brain networks, including circuits that control motivation and responses to rewarding and aversive stimuli. Furthermore, the serotonin system is tar...
Learning Modulates Early Encephalographic Responses to Distracting Stimuli: A Combined SSVEP and ERP Study
Through experience, humans can learn to suppress locations that frequently contain distracting stimuli. However, the neural mechanism underlying learned suppression remains largely unknown. In this st...
Leptin Activates Dopamine and GABA Neurons in the Substantia Nigra via a Local Pars Compacta-Pars Reticulata Circuit
Adipose-derived leptin contributes to energy homeostasis by balancing food intake and motor output, but how leptin acts in brain motor centers remains poorly understood. We investigated the influence...
Sensorimotor Transformations for Postural Control in the Vermis of the Cerebellum
The cerebellar vermis plays an essential role in maintaining posture and balance by integrating sensory inputs from multiple modalities to effectively coordinate movement. By transforming convergent s...
Neocortical and Hippocampal Theta Oscillations Track Audiovisual Integration and Replay of Speech Memories
“Are you talkin’ to me?!” If you ever watched the masterpiece “Taxi Driver” directed by Martin Scorsese, you certainly recall the monologue during which Travis Bickle rehearses an imaginary confrontat...
Differentiating Reinforcement Learning and Episodic Memory in Value-Based Decisions in Parkinson's Disease
Patients with Parkinson's disease (PD) are impaired at incremental reward-based learning. It is typically assumed that this impairment reflects a loss of striatal dopamine. However, many open question...
Macroscale Traveling Waves Evoked by Single-Pulse Stimulation of the Human Brain
Understanding the spatiotemporal dynamics of neural signal propagation is fundamental to unraveling the complexities of brain function. Emerging evidence suggests that corticocortical-evoked potential...
Evidence That Respiratory Phase May Modulate Task-Related Neural Representations of Visual Stimuli
We investigate how respiration influences cognition by examining the interaction between respiratory phase and task-related brain activity during two visual categorization tasks. While prior research...
EEG of the Dancing Brain: Decoding Sensory, Motor, and Social Processes during Dyadic Dance
Real-world social cognition requires processing and adapting to multiple dynamic information streams. Interpreting neural activity in such ecological conditions remains a key challenge for neuroscienc...