Journal of Neuroscience

Designing Globally Inclusive and Ethically Deliberate Neurofutures

Unlike any other organ, the brain's role in identity, agency, and experience makes it biologically and culturally unique. The transformative potential of global neuroscience demands robust, integrated...

False Percepts as a Window onto Visual Processing

Erratum: Huang et al., “Calcineurin and CK2 Reciprocally Regulate Synaptic AMPA Receptor Phenotypes via α2δ-1 in Spinal Excitatory Neurons”

Erratum: Kim et al., “GABAergic/Glycinergic and Glutamatergic Neurons Mediate Distinct Neurodevelopmental Phenotypes of <i>STXBP1</i> Encephalopathy”

Autophagy Is Required for Dopaminergic Axon Development and Confers Their Responsiveness to Guidance Cues

Midbrain dopamine (mDA) neurons play a wide range of brain functions, but the molecular mechanisms driving the formation of mDA circuits remain largely unknown. Here, we show that autophagy, the main...

Insular Input to the Prelimbic Cortex Underlies Social Affective Behavior in Rats

To navigate social interactions, animals must adjust their behavior in response to information derived from conspecifics. The integration of social information and coordination of behavior occurs with...

Inhibition of Return without Preparatory Suppression in Spatial Priority Maps

Visual attention is thought to operate via spatial priority maps that enhance attended locations and suppress distractors. While sustained enhancement is well established, whether priority maps can ma...

Motor-to-Limbic Design of Direct Synaptic Communication between Dopamine Neurons in the Midbrain

Midbrain dopamine (DA) neurons are diverse with distinct subpopulations being essential for key functions of the brain: nigrostriatal DA neurons for voluntary movement and mesolimbic DA neurons for le...

Genetically Encoded Constitutive Upregulation of β2 Subunit-Containing Neuronal Nicotinic Acetylcholine Receptors Is Neuroprotective in Female Parkinsonian Mice

Parkinson's disease is projected to rise to pandemic proportions by 2050, which has resulted in an urgent need for disease-modifying treatments. We previously showed that in a mouse model of parkinson...

Mechanisms and Cell Type-Dependence of Non-Hebbian Long-Term Potentiation at Primary Afferent Synapses in the Mouse Spinal Superficial Dorsal Horn

Sensory synapses onto ascending spinal projection neurons in the superficial dorsal horn (SDH) can exhibit non-Hebbian plasticity, such as when the firing of primary afferent neurons alone is sufficie...

Spontaneous Eye Movements Following Touch Reflect Canonical Body Postures

Humans constantly move when interacting with their environment. This constant movement challenges the processing of tactile stimuli because localizing tactile input on the body requires considering po...

Voluntary Dissociation of Motor Unit Activity in the Vastii Muscles

The central nervous system controls movement with consistent activation patterns across muscles and motor units (MUs), suggesting the presence of a relatively fixed and high-dimensional number of neur...

Beta and Gamma Dynamics in Attentional Networks Predict Conscious Reports

What neural events precede conscious reports? Hemisphere-asymmetric attentional networks are causally related to conscious perception (Kaufmann et al., 2024; Bartolomeo et al., 2025), but their spectr...

Timbre Encoding in the Inferior Colliculus

Timbre, or the quality of a sound, is a critical component in speech and music. One percept of timbre, brightness, is correlated with the spectral centroid and the spectral envelope of harmonic sounds...

Attentional Disengagement during External and Internal Distractions Reduces Neural Speech Tracking in Background Noise

Within-situation disengagement—the mental withdrawal during conversations in acoustically challenging environments—is a common experience of older people with hearing difficulties. Yet, most research...

Timing, Movement, and Reward Contributions to Prefrontal and Striatal Ramping Activity

Across species, prefrontal and striatal neurons exhibit time-dependent ramping activity, defined as a consistent monotonic change in the firing rate across temporal intervals. However, it is unclear i...