Journal of Neuroscience
Articles in this Issue
<i>Alyref</i> Deficiency Exacerbates Chronic Inflammatory Pain by Impairing Nuclear Export of <i>Ccn3</i> mRNA
The 5-methylcytosine (m 5 C) RNA modification regulates multiple aspects of RNA metabolism; however, its contribution to pathological pain remains poorly unders...
Late Endosome Transport by RILP-RAB7A Promotes Dendrite Arborization Independently of Degradation
Directional dendritic transport of late endosomes (LEs) retrogradely toward the soma is required for fusion with lysosomes and for degradation in the soma. Both dendritic motility of LEs and somatic d...
Pulvinar Subregions Influence Select Cortical Pathways in Humans
The pulvinar is a large, multisensory thalamic hub with distinct subregions and widespread cortical connectivity. This widespread connectivity is thought to regulate the flow of information across the...
Neural Population Dynamics in Primate Multisensory Cortical Areas during Heading Discrimination
Cortical areas involved in self-motion perception process cues from multiple sensory modalities, primarily visual and vestibular, alongside choice-related activity. Neurons in these regions often resp...
Presynaptic Vesicles Supply Membrane for Axonal Bouton Enlargement during Long Term Potentiation
Long-term potentiation (LTP) induces presynaptic bouton enlargement and a reduction in the number of synaptic vesicles. To understand the relationship between these events, we performed 3D analysis of...
Auditory Cortex Distinguishes between Spontaneous and Sound-Evoked Movements
Activity in sensory cortex is influenced by multiple factors beyond sensory input, including body movements, neuromodulatory signals, and internal states such as arousal. Focusing on brief whisking bo...
The Human Cerebellum Encodes Temporally Sensitive Reinforcement Learning Signals
In addition to supervised motor learning, the cerebellum also supports nonmotor forms of learning, including reinforcement learning (RL). Recent studies in animal models have identified core RL signal...
A Topological Fingerprint Encodes Motor Skill at Rest
In this study, we investigated whether the architecture of brain interactions at rest maintains a representation of individual behavioral skills. Specifically, we aimed to identify a minimal set of to...
Expression and Localization of NMDA Receptor GluN2 Subunits in Dorsal Horn Pain Circuits across Sex, Species, and Late Postnatal Development
Despite being essential mediators of pain processing, the molecular identity of N -methyl- d -aspartate receptor (NMDAR)...
A Matter of Parameters: Tailored Transcranial Focused Ultrasound Enhances Cortico-Thalamo-Cortical Circuit Resonance
A Shared Neural Mechanism for Abstract Grammatical Computations across Languages in Bilinguals
A central question in cognitive neuroscience is how the brain implements abstract computations that must generalize across superficially different inputs. Language provides a strong test case: the sam...