Journal of Neuroscience

A Distributional Reinforcement Learning Framework for Value Representation in Opioid Use Disorder

This Week in The Journal

Real-Time Brain-State-Coupled Corticocortical Paired Associative Stimulation of Cognitive Networks

Brain networks coordinate distributed neuronal assemblies to support cognition. Spike-timing-dependent plasticity (STDP) and neuronal oscillations are key substractes for state-gated learning rules th...

Erratum: Zhao et al., “Domain-General Neural Effects of Associative Learning and Expectations on Pain and Hedonic Taste Perception”

Revisiting Face-to-Hand Area Remapping in the Human Primary Somatosensory Cortex after a Cervical Spinal Cord Injury

Spinal cord injury (SCI) leads to profound disruptions in sensorimotor processing. Seminal research in nonhuman primates suggests this sensory deprivation causes functional remapping in the primary so...

Working Memory Deficits in Hippocampal Amnesia are Associated with Apathy

The hippocampus is increasingly recognized for its role in working memory representations and goal-directed behavior, yet whether these functions share common neural substrates remains unclear. We inv...

Hypothalamic Glutamatergic/Orexinergic Neurons Attenuate Fentanyl-Induced Respiratory Depression via Medullary Pre-BöTzinger Complex Pathways

Opioid-induced respiratory depression, particularly from fentanyl, is a major contributor to overdose mortality. The hypothalamus plays a modulatory role in breathing, potentially via orexinergic and...

Dynamics of Dentate Gyrus Place Cells and Dentate Spikes during Spatial and Nonspatial Changes in Environments

The dentate gyrus (DG) is thought to play a key role in the formation of dissociable memory representations for similar contexts. Neurons in the DG receive highly processed spatial and nonspatial sens...

Motor Prediction Reduces Beta-Band Power and Enhances Cerebellar–Somatosensory Connectivity before Self-Touch to Enable Its Attenuation

Motor control theories suggest that the brain uses forward models to predict self-generated tactile input during voluntary movements, thereby reducing the intensity of reafferent tactile sensations. W...

Delay Selection by Spike-Timing-Dependent Plasticity Shapes Efficient Networks for Signal Transmission

Information processing in the brain relies on efficient communication between different brain regions. Brain oscillations can control signal transmission in brain networks by modulating the timing and...

Plasticity in Thoracic Paravertebral Sympathetic Postganglionic Neurons after High Spinal Cord Transection

Various presympathetic descending brain circuits recruit spinal cord preganglionic neurons to encode central sympathetic drive via their synaptic actions onto sympathetic postganglionic neurons (SPNs)...

Developmental Changes to the M-Current Shape the Direction of Its Neuromodulation in Zebrafish Motoneurons

Movements during development are refined through ongoing maturation of the spinal circuits that mediate them. In many vertebrates, including zebrafish, this maturation process involves neuromodulators...

Increased Self-Grooming Gates Adult Visual Cortical Plasticity through a Ventral Pallidum–Visual Cortex Pathway

Repetitive behaviors are prominent features of multiple neurodevelopmental and psychiatric disorders, which are frequently accompanied by abnormalities in visual processing. However, whether repetitiv...

Decoding Orientation Serial Dependence from V1/V2 Population Responses Using a Cross-Attention Transformer

Perception of visual orientation is shaped by not only the current stimulus but also the recent history, showing repulsive biases or attractive serial dependence biases. Although repulsion is often as...