Journal of Neuroscience
Articles in this Issue
Neural Representation of Fear Experience Is Shaped by Context
Superior Colliculus Projections Drive Dopamine Neuron Activity and Movement But Not Value
To navigate dynamic environments, animals must rapidly integrate sensory information and respond appropriately to gather rewards and avoid threats. It is well established that dopamine (DA) neurons in...
Hippocampal Ripples during Offline Periods Predict Human Motor Sequence Learning
High-frequency bursts in the hippocampus, known as ripples (80–120 Hz in humans), have been shown to support episodic memory processes. However, converging recent evidence in rodent models and human n...
Q Neuron-Induced Hypothermia Promotes Functional Recovery and Suppresses Neuroinflammation after Brain Injury
Traumatic brain injury (TBI) triggers a cascade of secondary pathologies—such as neuroinflammation and glial activation—contributing to progressive neuronal loss and hindering functional recovery. Whi...
Motor Control Processes Moderate Visual Working Memory Gating
Gating processes that regulate sensory input into visual working memory (WM) and the execution of planned actions share neural mechanisms, suggesting a mutual interaction. In a preregistered study (Op...
Altered Electrophysiology and Transcriptome of GnRH Neurons in Middle-Aged Female Mice
Aging affects the reproductive system, although its impact on GnRH neurons is mainly unexplored. Thus, we compared the transcriptome and electrophysiology of GnRH neurons obtained from female middle-a...
Joint Population Coding and Temporal Coherence Link an Attended Talker’s Voice and Location Features in Naturalistic Multi-talker Scenes
Listeners effortlessly extract multi-dimensional auditory objects, such as a localized talker, from complex acoustic scenes. However, the neural mechanisms that enable simultaneous encoding and linkin...
Effects of Partial Occlusion on Response Dynamics and Interregional Processing within Primate Superior Temporal Sulcus
Recognizing partially occluded objects is a critical visual function that primates perform with ease, yet the underlying neural mechanisms remain incompletely understood. Previous studies in the macaq...
Hippocampal Drift Rate Reflects the Temporal Organization of Memories
When freely recalling past events, individuals tend to successively remember stimuli that were studied close together in time—a phenomenon known as temporal clustering. Temporal clustering is thought...
Distinct Ultrastructural Properties and Plasticity of Synapses Formed by Adult-Born and Early-Born Interneurons in the Mouse Olfactory Bulb
The olfactory bulb (OB) is one of the few regions in the adult brain that receives newly generated neuronal precursors throughout the lifespan of animals. These neuronal precursors differentiate into...
Disentangling the Functional Roles of Premotor–Motor Pathways in Automatic Imitation: A Combined Network-Based Transcranial Stimulation and Drift Diffusion Modeling Approach
Humans have an automatic tendency to imitate others’ actions, a process facilitated by the action observation network (AON). While motor nodes of the AON, such as the ventral premotor cortex (PMv) and...
Noise-Induced Hearing Loss Enhances Ca <sup>2+</sup> -Dependent Electrical Activity in Lateral Cochlear Efferents
Exposure to loud and/or prolonged noise damages the cochlea and triggers downstream brain changes, resulting in hearing loss and altered speech comprehension. It remains unclear however whether noise...
Sharp Waves, Bursts, and Coherence: Activity in a Songbird Vocal Circuit Is Influenced by Behavioral State
Similar to motor skill learning in mammals, vocal learning in songbirds requires a set of interconnected brain areas that make up an analogous basal ganglia–thalamocortical circuit known as the anteri...
Synaptic Properties of Layer 6 Auditory Corticothalamic Inputs in Normal Hearing and Noise-Induced Hearing Loss
Layer 6 corticothalamic neurons (CTs) provide strong feedback input that is crucial to perception and cognition in normal and pathological states; however, the synaptic properties of this input remain...
Origins of the Auditory Brainstem Response in Mice Using Source Localization of Topographic Multichannel EEG
The auditory brainstem response (ABR) is a critical tool for assessing auditory brainstem function in biomedical mouse models. Remarkably, despite its importance, the origins of ABR waves specific to...