Journal of Neuroscience
Articles in this Issue
A Normative Account of 3D Motion Perception from Natural Scenes
Erratum: Ostroff et al., “Combined Active Humoral and Cellular Immunization Approaches for the Treatment of Synucleinopathies”
Exploring Neural Dynamics in the Auditory Telencephalon of Crows Using Functional Ultrasound Imaging
Crows, renowned for advanced cognitive abilities and vocal communication, rely on intricate auditory systems. While the neuroanatomy of corvid auditory pathways is partially explored, the underlying n...
HDAC3 Serine 424 Phospho-mimic and Phospho-null Mutants Bidirectionally Modulate Long-Term Memory Formation and Synaptic Plasticity in the Adult and Aging Mouse Brain
Long-term memory (LTM) formation is negatively regulated by histone deacetylase 3 (HDAC3), a transcriptional repressor. Emerging evidence suggests that posttranslational phosphorylation of HDAC3 at it...
Oddball Evoked Deviant Responses Reflect Complex Context-Dependent Expectations in Mouse V1
Evoked responses in the mouse primary visual cortex can be modulated by the temporal context in which visual inputs are presented. Oddball stimuli embedded in a sequence of regularly repeated visual e...
Neuropathic Pain-Like Responses in a Chronic CNS Injury Model Are Mediated by Corticospinal-Targeted Spinal Interneurons
Chronic neuropathic pain is a persistent and debilitating outcome of traumatic central nervous system injury, affecting up to 80% of individuals. Postinjury pain is refractory to treatments due to the...
Is It Me or the Train Moving? Humans Resolve Sensory Conflicts with a Nonlinear Feedback Mechanism in Balance Control
Humans use multiple sensory systems to estimate body orientation in space. Sensory contributions change depending on context. A predominant concept for the underlying multisensory integration (MSI) is...
Increased Neuronal Expression of the Early Endosomal Adaptor APPL1 Replicates Alzheimer’s Disease-Related Endosomal and Synaptic Dysfunction with Cholinergic Neurodegeneration
Endosomal system dysfunction within neurons is a prominent early feature of Alzheimer's disease (AD) pathology. Multiple AD risk factors are regulators of endocytosis and known to cause hyperactivity...
Change of Spiny Neuron Structure in the Basal Ganglia Song Circuit and Its Regulation by miR-9 during Song Development
Juvenile zebra finches learn to sing by imitating conspecific songs of adults during a sensitive period early in life. Area X is a basal ganglia nucleus of the song control circuit specialized for son...
V2b Neurons Act via Multiple Targets to Produce in Phase Inhibition during Locomotion
Spinal interneurons shape motor neuron activity. Gata3+ V2b neurons are a major inhibitory spinal population. These neurons are present at multiple spinal levels in mice, suggesting an important funct...
Phospho-CREB Regulation on NMDA Glutamate Receptor 2B and Mitochondrial Calcium Uniporter in the Ventrolateral Periaqueductal Gray Controls Chronic Morphine Withdrawal in Male Rats
Opioid use disorder (OUD) is a chronic disease of the brain, and it currently continues at crisis proportions in the United States. Opioid physical withdrawal is a major driver of compulsive drug-taki...
Positron Emission Tomography (PET) Neuroimaging of the <i>Pink1-/-</i> Rat Parkinson Disease Model with the Norepinephrine Transporter (NET) Ligand [<sup>18</sup>F]NS12137
Evidence suggests that the neurotransmitter norepinephrine may play an important role in Parkinson disease (PD). The norepinephrine transporter (NET) regulates noradrenergic signaling and can serve as...