Journal of Neuroscience
Articles in this Issue
Unraveling Pallido-Retrorubral Circuits Linking the Basal Ganglia to Limbic Areas
Role of Hypothalamic CRH Neurons in Regulating the Impact of Stress on Memory and Sleep
Stress profoundly affects sleep and memory processes. Stress impairs memory consolidation and, similarly, disruptions in sleep compromise memory functions. Yet, the neural circuits underlying stress-i...
Functional Autapses Selectively Form in a Subpopulation of Subicular Pyramidal Cells in Hippocampal Formation
Autapses are self-synapses formed by a single neuron. They selectively form in a subpopulation of neocortical glutamatergic pyramidal cells (PCs) where autaptic transmission provides strong feedback r...
Salience Signaling and Stimulus Scaling of Ventral Tegmental Area Glutamate Neuron Subtypes
Ventral tegmental area (VTA) glutamatergic neurons participate in reward, aversion, drug-seeking, and stress. Subsets of these neurons cotransmit glutamate and GABA (VGluT2 +...
Atypical Retinal Ganglion Cell Function in a Mouse Model of Fragile X Syndrome
The altered function of peripheral sensory neurons is an emerging mechanism for symptoms of autism spectrum disorders. Visual sensitivities are common in autism, but whether differences in the retina...
Novel Insights into Emx2 and Dmrta2 Cooperation during Cortex Development and Evidence for Dmrta2 Function in the Choroid Plexus
Early dorsal telencephalon development is coordinated by an interplay of transcription factors that exhibit a graded expression pattern in neural progenitors. How they function together to orchestrate...
Bitter Sensing Protects<i>Drosophila</i>from Developing Experience-Dependent Cocaine Consumption Preference
Cocaine is an addictive psychostimulant, and the risk of developing cocaine use disorder (CUD) is highly heritable. Little is known about the specific genes and mechanisms that lead to the development...
Neurophysiological Evidence of Sensory Prediction Errors Driving Speech Sensorimotor Adaptation
The human sensorimotor system has a remarkable ability to learn movements from sensory experience. A prominent example is sensorimotor adaptation, learning that characterizes the sensorimotor system's...
Brain–Behavior Differences in Premodern and Modern Lineages of Domestic Dogs
Although domestic dogs were the first domesticated species, the nature of dog domestication remains a topic of ongoing debate. In particular, brain and behavior changes associated with different stage...
Opioid Receptors Modulate Inhibition within the Prefrontal Cortex through Dissociable Cellular and Molecular Mechanisms
Aberrant signaling within cortical inhibitory microcircuits has been identified as a common signature of neuropsychiatric disorders. Interneuron (IN) activity is precisely regulated by neuromodulatory...