Journal of Neuroscience
Articles in this Issue
Social Reward Learning Deficits and Concordant Brain Alterations in Rats Overexpressing Disrupted-in-Schizophrenia 1 (DISC1)
Social deficits are a hallmark of schizophrenia, often characterized by impairments in processing and integrating socially transmitted information. However, translational models that accurately captur...
Attentional Mechanisms for Learning Feature Combinations
Linking Connectivity Dynamics to Symptom Severity and Cognitive Abilities in Children with Autism Spectrum Disorder: An FNIRS Study
Functional near-infrared spectroscopy (fNIRS) has emerged as a valuable tool for investigating neurobiological markers in children with autism spectrum disorder (ASD). While previous studies have iden...
Rebound Bursting Selectively Enables Fast Dynamics in Dopamine Midbrain Neurons Projecting to the Dorsolateral Striatum
Dopamine (DA) midbrain neurons are involved in a wide array of key brain functions including movement control and reward-based learning. They are also critical for major brain disorders such as Parkin...
Tonic GABA and Glycine Inhibition Control Pain Hypersensitivity via Limiting α2δ-1– and mGluR5–Dependent NMDA Receptor Activity at Primary Afferent→Excitatory Neuron Synapses
Impaired synaptic inhibition by GABA and glycine contributes to excitatory–inhibitory imbalance in the spinal cord associated with chronic neuropathic pain; however, the underlying mechanisms remain u...
Alpha-Band Activity Tracks Reflexive Changes in the Breadth of the Zoom Lens of Attention
Spatial attention is often conceptualized as a flexible “zoom lens” that can dynamically adjust its focus, but most evidence stems from studies of voluntary attention. Our study investigates whether i...
Exposure to Bullying Engages Social Distress Circuits in the Adolescent and Adult Brain
Despite advances in understanding the psychological and social consequences of peer victimization, the immediate effects of bullying on the central nervous system remain elusive. Here we mapped the ne...
Evidence for an Active Handoff between Hemispheres during Target Tracking
The brain has somewhat separate cognitive resources for the left and right sides of our visual field. Despite this lateralization, we have a smooth and unified perception of our environment. This rais...
Bltp1 Is Required for Survival and Normal Development and Function of the Neuromuscular Junction in Mice
BLTP1 (Bridge-Like Lipid Transfer Protein Family Member 1), previously known as Tweek, Kiaa1109, FSA, or 4932438A13Rik, is a nonvesicular lipid transport protein linked to Alkuraya–Kučinskas syndrome...
Switching Patterns of Cortical–Subcortical Interaction in the Human Brain
It is still poorly understood how subcortical structures contribute to spontaneous infraslow brain activity. In fact, cortical spontaneous activity is often analyzed in isolation, possibly a result of...
Sensory Deficits in Mice with Lateral Spinal Cord Hemisection Mimic the Brown–Séquard Syndrome
Spinal cord injury (SCI) often results in permanent sensory deficits, significantly impairing the quality of life. These deficits are poorly addressed due to a lack of valid animal models with transla...
Spatiotemporal Evidence Accumulation Through Saccadic Sampling for Object Recognition
Visual object recognition has been extensively studied under fixation conditions, but our natural viewing involves frequent saccadic eye movements that scan multiple local informative features within...
Spatiotemporal Dynamics of Lateral Na <sup>+</sup> Diffusion in Apical Dendrites of Mouse CA1 Pyramidal Neurons
Sodium ions (Na + ) are major charge carriers mediating neuronal excitation and play a fundamental role in brain physiology. Glutamatergic synaptic activity is...