Proceedings of the National Academy of Sciences
Articles in this Issue
In search of exotic pairing in the Hubbard model: Many-body computation and quantum gas microscopy
Finite-momentum pairing, exemplified by Fulde–Ferrell–Larkin–Ovchinnikov (FFLO) states, represents a paradigmatic form of unconventional superfluidity driven by Fermi-surface mismatch, but its detecti...
Non-cell-autonomous mechanisms of tumor initiation and relapse by chromosomal instability
Chromosomal instability (CIN) is a hallmark of cancer, and a primary cause of genetic heterogeneity in tumors. Depending on the degree of CIN and the affected tissue, CIN can promote or suppress tumor...
Mathematical modeling of <i>JAK2V617F</i> clonal expansion in a general population cohort
The Philadelphia chromosome-negative myeloproliferative neoplasms (MPNs) are a group of blood cancers characterized by overproduction of one or more types of blood cells, which can lead to thrombosis...
The dynamic mesoscale sink and source niches for eukaryotic phytoplankton in a subtropical gyre
By tracking the water mass histories of genetic samples, we investigated the biophysical dynamics shaping eukaryotic phytoplankton populations in a nutrient-deplete subtropical gyre, where cyanobacter...
Defiance of stable lysogeny reveals hidden infection dynamics of phage Lambda
Stable prophage establishment is considered a quintessential response of temperate phages when faced with host cell depletion. Scrutinizing this behavior in model phage λ, however, revealed that many...
<i>Pyrodictium abyssi</i> AbpX reveals a calcium-responsive family of microbial biomatrix proteins that form thermostable hydrogels
Evolutionary pressure on microbial communities propagating under extreme environmental conditions often results in unique structural adaptations to promote cell survival. Here, we report an investigat...
FcRL4 is an IgA receptor that primarily binds the joining chain
Immunoglobulin A (IgA) is a crucial component of the human immune system, and its interaction with receptors is essential for immune regulation. Fc-receptor-like 4 (FcRL4) is an IgA receptor that sele...