Proceedings of the National Academy of Sciences
Articles in this Issue
Characterization of endothelin-converting enzyme 1 as a key enzyme in the multienzyme Aβ degradation pathway
Altered β-amyloid (Aβ) homeostasis is a critical event triggering the shift from healthy aging to Alzheimer disease (AD) through the overproduction and impaired clearance of Aβ peptides. The Aβ-degrad...
Learning expectations shape cognitive control allocation
Current models frame the allocation of cognitive control as a process of expected utility maximization. The benefits of a candidate control signal are weighed against its costs (e.g., opportunity cost...
Flagellar location determines the stability of bacterial surface entrapment
Surface interactions play a crucial role in shaping the motility patterns and ecological adaptations of swimming bacteria. Previous studies have primarily focused on peritrichous bacteria like...
Impactor relics of CI-like chondrites in Chang’e-6 lunar samples
The impact history of the Moon provides the opportunity to better understand mass transfer in the Solar System. While Earth’s meteorite collection serves as a key reference for material flux in the Ea...