Proceedings of the National Academy of Sciences
Articles in this Issue
Long-term climate warming weakens positive plant biomass responses globally
Carbon sequestration through plant biomass responses to global warming plays a vital role in mitigating climate change, but recent evidence suggests that this effect diminishes in the long term. To in...
Elucidating the role of <i>Campylobacter concisus</i> –derived indole metabolites in gut inflammation and immune modulation
The gut microbiota plays a pivotal role in maintaining human health with dysbiosis linked to a variety of diseases. Metagenome sequencing and robust statistical analysis have linked specific strains,...
CO <sub>2</sub> upgrading into bioproducts using a two-step abiotic–biotic system
The valorization of CO 2 to chemicals beyond C 1-2 products is receiving significant interest; however, the direct elect...
Warming climate and water withdrawals threaten river flow connectivity in China
River flow connectivity, the continuity of fluvial discharge in space and time, provides a crucial lifeline for most biotic communities on Earth. Yet there is still limited understanding of the impact...
Interhemispheric resting-state functional connectivity correlates with spontaneous neural interactions
Functional connectivity (FC), a statistical correlation of pair-wise brain signals from resting-state (RS) functional MRI (fMRI), is a widely used concept for mapping large-scale functional networks i...
Climate variability amplifies the need for vector-borne disease outbreak preparedness
In locations that do not currently experience vector-borne disease (VBD) outbreaks but may be at risk under climate change, modeling future climate suitability for transmission is important for outbre...
Cognitive bridge between geometric and numerical learning in monkeys
Educational research highlights strong developmental links between numerical and spatial cognition in humans, often shaped by cultural tools like the number line. However, emerging evidence suggests t...
Liquid water might not be the only answer: Evaluating pore-filling materials in the Martian crust
Rediscovering fire
Reply to Xiao et al.: A wet or dry Martian mid-crust, that is only part of the question
Solstice, selection, and synchrony of seed masting
Landscape changes elevate the risk of avian influenza virus diversification and emergence in the East Asian–Australasian Flyway
Highly pathogenic avian influenza viruses (HPAIV) persistently threaten wild waterfowl, domestic poultry, and public health. The East Asian–Australasian Flyway plays a crucial role in HPAIV dynamics d...
Inbreeding reduces fitness in spatially structured populations of a threatened rattlesnake
Small and fragmented populations are at high risk of local extinction, in part because of elevated inbreeding and subsequent inbreeding depression. A major conservation priority is to identify the mec...
A tubulin–MAPKKK pathway engages tubulin isotype interaction for neuroprotection
The microtubule (MT) cytoskeleton is essential for neuronal morphology, neurite growth, synapse formation and maintenance, as well as regulation of signal transduction. Most cells express multiple iso...