Blood
Articles in this Issue
Outcomes with ponatinib in patients with relapsed/refractory Philadelphia-chromosome positive acute lymphoblastic leukemia: A systematic review and meta-analysis
Abstract Introduction: Outcomes in Philadelphia chromosome–positive acute lymphoblastic leukemia (Ph+ ALL) have improved significantly with...
MPN (Myeloproliferative Neoplasm) journal: A platform developed by MPN patients for MPN patients to track their disease, aid communication with healthcare team and create a dataset for patient data analytics
Abstract Background: The MPNs; including the specific diseases of essential thrombocythemia (ET), polycythemia vera (PV), and myelofibrosis...
Prognosis prediction beyond MTV using easy to calculate parameters derived from FDG-PET/CT, a pilot Study
Abstract Introduction: Total metabolic tumor volume (MTV) is a well-established prognostic biomarker in diffuse large B-cell lymphoma (DLBCL)...
Efficacy and safety of pivekimab sunirine in combination with venetoclax plus azacitidine in unfit patients with newly diagnosed Acute Myeloid Leukemia
Abstract Introduction: While newly diagnosed patients (pts) with acute myeloid leukemia (AML) who are ineligible for intensive chemotherapy...
Safety and efficacy of CD3xCD20 bispecific antibody for the treatment of primary and secondary central nervous system lymphoma patients: A multicentric retrospective study
Abstract Introduction: Relapsed/refractory (R/R) central nervous system involvement (CNS) of aggressive B cell lymphoma presents a dismal pr...
A single-center retrospective study of golidocitinib for the treatment of peripheral T-cell lymphoma
Abstract Background Peripheral T-cell lymphoma (PTCL) is a highly heterogeneous and aggressive type of non-Hodgkin lymph...
New chronic lymphocytic leukaemia therapies: Does measurable residual disease testing accurately predict progression-free survival
Abstract Measurable residual disease (MRD)-testing is often used to evaluate therapy efficacy in chronic lymphocytic leukaemia (CLL), with u...
Ex vivo-generated T cell precursors enhance thymic regeneration and T cell immunity after allogeneic hematopoietic cell transplantation
Abstract Delayed immune reconstitution following allogeneic hematopoietic cell transplant (allo-HCT) increases the risk of infection, graft...
Outcomes of HLA-matched unrelated versus haploidentical hematopoietic cell transplantation in acute leukemia: A multicenter observational study in Brazil facilitated by the CIBMTR
Abstract Background: While several studies from high-income countries have evaluated hematopoietic cell transplantation (HCT) using haploide...
Effect of isatuximab use in combination with autologous stem cell transplant on mobilized stem cell product and post-transplant immune recovery - Results of a randomized prospective Phase 2 trial
Abstract Background: Autologous stem cell transplantation (ASCT) in hematological malignancies remains an important therapy for eligible pati...
Utilization of guidelines and educational resources in telomere biology disorders: Patterns of information-seeking behaviors and knowledge translation among clinicians and families
Abstract Background: Telomere Biology Disorders (TBDs) are characterized by critically short telomeres due to pathogenic germline variants i...
Oral etoposide vs intravenous daunorubicin plus ATRA-RIF as induction therapy for low-risk acute promyelocytic leukemia: A phase II randomized controlled Trial
Abstract Introduction Despite all-trans retinoic acid (ATRA) -arsenical regimens achieve high cure rates in low-risk APL, relapse persists a...
Efficacy and Safety of ATRA+ATO/RIF+venetoclax combination therapy in the treatment of adult acute promyelocytic leukemia
Abstract Objective: To evaluate the efficacy and safety of the triple-combination therapy consisting of all-trans retinoic acid (ATRA), arse...
Outcomes in children with NCI standard-risk b-acute lymphoblastic leukemia treated with intensified post-induction therapy: Results from Children's Oncology Group studies AALL0932 and AALL1131
Abstract Introduction End of induction (EOI) positive minimal residual disease (MRD) and unfavorable sentinel genetic lesions predict poor o...
Grade I acute graft-vs-host disease: Treat or not?
Abstract Background Acute graft-versus-host disease (GVHD) is a major cause of non-relapse mortality (NRM) after allogeneic hematopoietic ce...
Phase I study of lower dose CPX-351 combined with venetoclax for patients with higher-risk myelodysplastic syndrome or chronic myelomonocytic leukemia after hypomethylating agents failure
Abstract Background: Patients (pts) with relapsed/refractory (R/R) higher-risk (HR) myelodysplastic syndrome (MDS) or MDS/myeloproliferative...
A Phase II trial of obinutuzumab, ibrutinib and venetoclax in patients with previously untreated follicular lymphoma; A University of California hematologic malignancies consortium study
Abstract Background Clinical management of advanced-stage follicular lymphoma (FL) remains highly variable with no universally accepted stan...
Fingolimod in combination with bortezomib demonstrates synergistic tumor inhibition and bone anabolic effects in myeloma bone disease
Abstract Background: Drug resistance and progressive bone destruction are the primary causes of morbidity and mortality in multiple myeloma...
Safety of abbreviated dose-escalation in patients (pts) receiving glofitamab (glofit) or epcoritamab (epcor)
Abstract Introduction Cytokine release syndrome (CRS) and immune effector cell-associated neurotoxicity syndrome (ICANS) are unique and pote...
The impact of immune thrombocytopenia on oral health: Let's talk
Abstract Introduction: The Immune Thrombocytopenia (ITP) World Impact Survey reported 40% of patients ranked gum bleeding as a severe sympto...
Immune thrombotic thrombocytopenic purpura in Armenia: A case series highlighting the role of early empiric therapy and multidisciplinary management
Abstract Immune thrombotic thrombocytopenic purpura (iTTP) is a rare but potentially fatal thrombotic microangiopathy characterized by sever...
Outcomes and resource utilization during and after oral anticoagulant-related bleeding in chronic kidney disease (ORACLE-CKD): A population-based cohort study
Abstract Background: In the United States, an estimated 37 million people have chronic kidney disease (CKD), which increases the risk of atr...
Post-transplant cyclophosphamide-based graft-verses-host disease (GVHD) prophylaxis is associated with a low incidence of fibrotic chronic GVHD after allogeneic hematopoietic cell transplantation across diverse donor types
Abstract Background: Chronic graft-versus-host disease (cGVHD) remains the leading cause of non-relapse mortality (NRM) in patients who unde...
Social determinants of health and late mortality among allogeneic blood or marrow transplant (BMT) survivors: A BMTSS report
Abstract Introduction: Conditional on surviving the first 2y after BMT, allogeneic BMT recipients remain at a 9-fold greater risk of late mo...
Ponatinib as a consolidation strategy for a second attempt at TKI discontinuation in chronic myeloid leukemia: Interim results from the restop Trial
Abstract INTRODUCTIONApproximately 30–50% of patients with chronic myeloid leukemia (CML) are eligible for tyrosine kinase inhibitor (TKI) d...