Blood
Articles in this Issue
Evaluation of psychosocial impact of myelodysplastic syndromes evaluation by self report
Abstract Myelodysplastic syndromes (MDS) are stem cell malignancies with diverse clinical presentations and variable prognoses. Patient-repo...
ML-driven analysis of iscn karyotypes enables detection of novel prognostic markers in chronic lymphocytic leukemia (CLL)
Abstract Background: Karyotyping by chromosome banding analysis (CBA) is standard-of-care in hematological malignancies...
The impact of Duffy genotype on progression-free survival (PFS) with lenalidomide, Bortezomib, and dexamethasone (RVd) alone or RVd plus autologous stem cell transplantation (ASCT) and continuous R maintenance in patients (pts) with newly diagnosed multiple myeloma (NDMM): Updated subgroup analysis of the phase 3 DETERMINATION trial
Abstract Background: A single nucleotide polymorphism (SNP) in ACKR1/DARC results in erythrocyte Duffy null phenotype in ~66% of African Ame...
Real-world evaluation of health care resource utilization, clinical effectiveness, and safety of lisocabtagene maraleucel and axicabtagene ciloleucel administered in the outpatient (OP) setting for R/R large B-cell lymphoma (LBCL)
Abstract Introduction: Use of CD19-directed CAR T cell therapies has transformed treatment of patients with LBCL. OP administration has the...
Key factors for the success of autologous hematopoietic stem cell transplantation in HIV-infected patients with lymphoproliferative diseases
Abstract Introduction: Modern antiretroviral therapy (ART) has increased the life expectancy of HIV patients, but 9% of the 40.1 million inf...
Mutational landscape of adult xanthogranuloma
Abstract Background Adult xanthogranuloma (AXG) is a rare clonal histiocytic neoplasm (HN) with a poorly defined mutatio...
High complicated incidence of Gilbert's syndrome in patients with thalassemia: Deserve earlier identification and less oversight
Abstract Thalassemia comprises a group of inherited disorders characterized by impaired synthesis of globin chains, leading to increased ery...
The clinical utility of COMET™ sequential immunofluorescence in lymphoma tissue diagnostics: Next generation diagnosis.
Abstract Background: Immunohistochemistry is essential to the pathological diagnosis of formalin-fixed paraffin-embedded (FFPE) tissue biops...
Risk factors for cytokine release syndrome and neurotoxicity in patients receiving epcoritamab or glofitamab for large B cell lymphoma: A multi-center, retrospective, real world analysis.
Abstract Introduction: CD20xCD3 bispecific antibodies (BsAb) have been approved for use in relapsed/refractory (RR) large B-Cell lymphomas (...
Impact of vitamin d deficiency on quality of life and clinical outcomes in patients with multiple myeloma
Abstract Background: Multiple myeloma (MM) is a plasma cell malignancy with multi-organ involvement, including renal impairment, anemia, and...
Molecular profile linked to resistance to hypomethilating agents plus venetoclax does not predict outcome in secondary Acute Myeloid Leukemia patients receiving CPX-351 induction.
Abstract Introduction Acute Myeloid Leukemia (AML) is a heterogeneous disease, driven by the serial acquisition of somatic mutations, that ma...
Number of cardiac deaths associated with ibrutinib versus zanubrutinib for the treatment of chronic lymphocytic leukemia: A European risk-based estimation
Abstract Introduction Bruton tyrosine kinase inhibitors include ibrutinib (first generation) and zanubrutinib (next-generation) are approved...
It's that time of the month: Menstrual suppression among adolescents and young adults with cancer and quality of life
Abstract Introduction: Adolescents and young adults (AYAs) with cancer have significantly worse health related quality of life (HRQL) than t...
Zanubrutinib is well tolerated and effective in acalabrutinib-intolerant patients with B-cell malignancies: A long-term follow-up
Abstract Introduction: While Bruton tyrosine kinase (BTK) inhibitors are a mainstay of treatment for B-cell malignancies, their use can be l...
Interim results from a multicenter trial assessing the clinical relevance of copy number aberrations detected by a shallow whole-genome sequencing analysis (LeukoPrint) in multiple myeloma.
Abstract Introduction Multiple myeloma (MM) is a malignancy of clonal plasma cells, accounting for 10% of hematologic malignancies. Both prim...
Young (35 years) matched sibling donors for allogeneic transplantation with post-transplantation cyclophosphamide in patients with secondary acute myeloid leukemia in first complete remission: A study from the ALWP/EBMT
Abstract Background: Allogeneic hematopoietic stem cell transplantation (HSCT) is a curative therapeutic option for secondary acute myeloid...
Parkinsonism and other non-immune effector cell-associated neurotoxicities related to BCMA-directed chimeric antigen receptor T-cell therapy
Abstract Background: In the setting of relapsed/refractory (R/R) multiple myeloma (MM), B-cell maturation antigen (BCMA) directed chimeric a...
Indoleamine 2,3-dioxygenase 1 (IDO1) promotes immune effector cell-associated neurotoxicity syndrome (ICANS) after CAR-T therapy by disrupting brain endothelial cell integrity via KYNU–AA–Wnt/β-catenin pathway
Abstract Background: Elevated serum tryptophan levels are observed in patients with immune effector cell-associated neurotoxicity syndrome (...
Usefulness of C5b9 deposition analysis for the diagnosis, treatment, and monitoring of patients with transplant-associated thrombotic microangiopathy
Abstract Background: Transplant-associated thrombotic microangiopathy (TA-TMA) is a life-threatening complication of allogeneic hematopoieti...
Disparities in palliative care consultation among hospitalized patients with diffuse large B-cell lymphoma in the United States: A national analysis from 2016–2022
Abstract Background: Diffuse large B-cell lymphoma (DLBCL) is the most common subtype of non-Hodgkin lymphoma and often requires intensive t...
Evaluating targeted long-read sequencing as a diagnostic tool for burkitt lymphoma
Abstract Introduction: While sporadic in developed countries, Burkitt lymphoma (BL) is endemic in resource-limited regions. Given the one-ye...
Longitudinal analysis of richter syndrome risk and survival in CLL: The role of targeted therapy and molecular markers. experience at the fondazione policlinico gemelli in rome.
Abstract Background: Richter Syndrome (RS) is the development of an aggressive lymphoma in patients (pts) with chronic lymphocytic leukemia...
Lymphovision: A lymphoma-specialized foundation model for histology-based lymphoma classification and subtyping
Abstract Background: Recent advances in computer vision have given rise to image foundation models (FMs), large-scale neural networks pre-tr...
Iron-deficiency anemia in premenopausal women: A comparative study of menstrual blood loss and malabsorptive etiologies
Abstract Introduction Intestinal iron malabsorption refers to the impaired uptake of dietary iron across the gastrointes...
Real-world outcomes with blinatumomab as a bridging therapy for allogeneic hematopoietic stem cell transplantation in relapsed/refractory or measurable residual disease-positive B-cell acute lymphoblastic leukemia: A CIBMTR database analysis
Abstract Background: Blinatumomab has been used as an effective therapy for the treatment of adult and pediatric patients in various setting...