Blood
Articles in this Issue
Patient-reported outcomes of avatrombopag for chronic immune thrombocytopenia: Interim analysis of the Phase 4 adopt study
Abstract Introduction: Avatrombopag (AVA) is a thrombopoietin receptor agonist (TPO-RA) widely approved for the treatment of patients with c...
Identification of predictive protein signatures of treatment-free remission in patients with chronic myeloid leukaemia
Abstract Introduction: In the DESTINY trial (NCT01804985) bone marrow (BM) samples were taken from 160 patients with chronic myeloid leukaem...
Trends in chronic lymphocytic leukemia mortality among patients with pneumonia in the United States (1999–2024): A CDC wonder database analysis
Abstract INTRODUCTION: Chronic lymphocytic leukemia (CLL) is a common hematologic malignancy among older adults, with pn...
Dose intensive regimen of CK0804 tregs in myelofibrosis
Abstract Background: Myelofibrosis (MF) is a clonal hematopoietic stem cell disorder marked by significant inflammation and immune deregulat...
Complement inhibition in pediatrics: Comprehensive infection analysis from a large pediatric single center
Abstract Background Complement inhibition (Ci) has revolutionized outcomes in disorders, such as paroxysmal nocturnal hemoglobinuria (PNH) a...
The dimorphism at the HLA-B leader and molecular HLA compatibility impact on haplo-HSCT: Experience of a single-center based on ptcy strategies
Abstract Introduction: The challenges of finding HLA-matched donors for hematopoietic stem cell transplantation (HSCT) has led to the increa...
Intravenous iron administration during sepsis: Outcomes, safety, and hemoglobin response
Abstract Background Sepsis is a life-threatening syndrome characterized by a dysregulated immune response and ensuing or...
Efficacy and safety of blinatumomab as frontline treatment for infant acute lymphoblastic leukemia
Abstract Background Infant acute lymphoblastic leukemia (IALL) is highly aggressive with poor prognosis, representing a key focus and challe...
Longitudinal analysis of first and subsequent-line tyrosine kinase inhibitor use in chronic myeloid leukemia: A 16-year single-center experience
Abstract Background Tyrosine kinase inhibitors (TKIs) have significantly improved outcomes in chronic myeloid leukemia (CML), leading to pro...
Identification of dynamic markers for multiple myeloma in patients with MGUS and T2DM
Abstract Introduction: Multiple myeloma (MM) is a common, incurable blood malignancy. It is consistently preceded by a precursor condition m...
Clinical features and prognostic model for adenovirus infection following allogeneic hematopoietic stem cell transplantation: Insights from a Chinese cohort
Abstract Introduction Adenovirus (AdV) infection is a potentially life-threatening complication following allogeneic hem...
Acquired hemophilia A associated with amlodipine use in a hypertensive patient: A case report
Abstract Hemophilia is a bleeding disorder characterized by deficiency of factors within the coagulation cascade. Typically, hemophilia is a...
Interim results of a multi-center clinical trial evaluating copy number aberrations via shallow whole-genome sequencing (LeukoPrint) in Acute Myeloid Leukemia
Abstract Introduction Treating acute myeloid leukemia (AML), a diverse group of hematological cancers affecting bone marrow and blood, remai...
A rare case of high-risk M4 Acute Myeloid Leukemia with ETV6::ABL1 rearrangement in a young adult with preceding chronic idiopathic thrombocytopenia: Insights and implications
Abstract Background: ETV6::ABL1 rearrangement is exceptionally rare in acute myeloid leukemia (AML), particularly in ped...
Trends and disparities in myeloid leukemia related mortality in the United States from 1968 to 2016: CDC wonder analysis
Abstract Background: Myeloid leukemia (ML), a heterogeneous group of hematologic malignancies, encompasses acute and chronic forms and remai...
Limited diagnostic utility of abdominal fat pad biopsy for systemic amyloidosis: A single institution's experience
Abstract Background: As a minimally invasive procedure, abdominal fat pad biopsy is commonly used as an initial diagnostic screening tool in...
Burden of comorbid conditions and hospital outcomes in sickle cell trait patients with atrial fibrillation: A retrospective nationwide analysis
Abstract Background: Sickle cell trait (SCT) is linked to worse cardiovascular and renal outcomes. Increased prevalence of atrial fibrillati...
Assessment of prolonged thrombocytopenia after CD19 CAR-T therapy: Evidence for reduced production
Abstract Introduction: Chimeric antigen receptor (CAR) T-cell therapy has shown high response rates and lasting remissions in some patients...
Lachnospiraceae-mediated bile acid metabolism promotes ileal epithelial regeneration following graft-versus-host disease damage
Abstract In allogeneic hematopoietic stem cell transplantation (allo-HSCT), complications such as graft-versus-host disease (GVHD) continue...
Patterns and clinical impacts of hematology electronic consults: A retrospective, single-center analysis
Abstract Background: With the several months wait for new patient appointments in hematology, many institutions have been exploring electron...
Apheresis blood processing with heparin improves stem cell collection outcomes for sickle cell gene therapy
Abstract The expansion of gene therapy (GT) for sickle cell disease (SCD) has underscored the critical need to collect large numbers of stem...
Hypomethylating agents or chemotherapy in combination with venetoclax and gilteritinib for FLT3-mutated Acute Myeloid Leukemia
Abstract BACKGROUND Triplet therapies with hypomethylating agents (HMA), venetoclax, and second-generation FLT3 inhibitors have demonstrated...
Subclinical cardiac changes following CPX-351 induction in adults with favorable/intermediate-risk AML
Abstract Background: CPX-351 is a liposomal formulation of daunorubicin and cytarabine, approved for the treatment of newly diagnosed therap...
Cost effectiveness of in-house HIT screening testing in community based hospital
Abstract Background Heparin-induced thrombocytopenia type II (HIT) is a rare but potentially life-threatening immune-mediated complication e...
A combination strategy of inotuzumab ozogamicin (InO) and BCL-2 family inhibitors prevents the emergence of PGP+ ino-resistant MRD in B-cell acute lymphoblastic leukemia
Abstract Background: Inotuzumab ozogamicin (InO) achieves a complete remission (CR) rate of over 60-80% in patients with relapsed/refractory...