Blood
Articles in this Issue
Incidence, patterns, and outcomes of adenovirus infections in patients following allogeneic hematopoietic cell transplantation
Abstract Background: Adenovirus (AdV) infection is a recognized complication following allogeneic hematopoietic cell tra...
The exact system for precision clinical trial matching: Case study of accuracy with follicular lymphoma trials
Abstract Introduction: Accurate clinical trial matching remains a major barrier to oncology trial enrollment, particularly due to the diffic...
Neutrophil count is an independent prognostic indicator in early T-cell precursor lymphoblastic leukemia
Abstract Purpose Early T-cell precursor lymphoblastic leukemia (ETP-ALL) is an immunophenotypically defined subgroup of T-ALL associated wit...
A Phase 1 study of KITE-753 or KITE-363 in patients with relapsed/refractory B-cell lymphoma: Initial safety and preliminary efficacy of KITE-753 and updated results of KITE-363
Abstract Introduction: KITE-363 and KITE-753 are dual-targeting, autologous chimeric antigen receptor (CAR) T-cell therapies designed to ove...
Trends and disparities in alzheimer's disease and anemia-related mortality in adults aged ≥ 65 years in the United States from 1999 to 2023: A CDC wonder database analysis
Abstract Introduction: Alzheimer's disease and anemia are both common among older adults in the United States and are linked to increased mo...
Epcoritamab monotherapy provides superior efficacy vs non–anthracycline-containing regimens in newly diagnosed elderly DLBCL patients deemed unsuitable for anthracycline-containing regimens: A match-adjusted comparative efficacy analysis
Abstract Introduction: Newly diagnosed diffuse large B-cell (DLBCL) patients (pts) who are older and/or have specific comorbidities may be u...
The role of palliative care in the multidisciplinary treatment of immunoglobulin light chain amyloidosis
Abstract Background: Immunoglobulin light chain (AL) amyloidosis is a plasma cell neoplasm characterized by deposition of intrinsically unst...
Impact of geographic distance and residential setting on overall survival in patients with Acute Myeloid Leukemia
Abstract Background: The treatment of acute myeloid leukemia (AML), particularly in the initial (induction) phase, is ty...
Prediction model for pediatric return visits for sickle cell disease post-emergency department discharge for acute pain
Abstract Introduction: Greater than one in four children with sickle cell disease (SCD) treated for pain in the emergency department (ED) re...
Real-world outcomes of mosunetuzumab use in indolent and aggressive lymphomas
Abstract Introduction Mosunetuzumab (mosun) is a CD20xCD3 bispecific antibody approved as a single agent for treatment of follicular lymphom...
Osteonecrosis risk in adult ALL: Insights from real-world clinical laboratory data in eighty-seven patients treated with peg-asparaginase
Abstract Acute lymphoblastic leukemia (ALL) is a potentially fatal disease treated with intensive multi-agent therapy. In Germany, treatment...
A phase II study of lenalidomide, zanubrutinib plus obinutuzumab in patients with FLIPI2 high-risk newly diagnosed follicular lymphoma: An interim analysis
Abstract Background Follicular lymphoma (FL) is the most common indolent non-Hodgkin lymphoma. Although rituximab plus l...
Red-lilly app: A digital tool for the evaluation of menstrual bleeding patterns to support the early detection of bleeding disorders in women
Abstract Background: According to the World Health Organization, approximately 18 million women are affected by heavy me...
Tocilizumab prophylaxis in patients receiving CAR-T cell immunotherapy for hematological malignancies: A systematic review and meta-analysis
Abstract Background: Chimeric antigen receptor-T (CAR-T) cell immunotherapy has revolutionized the therapeutic landscape for patients with r...
Integrated analysis of mogamulizumab trials for mature T-cell lymphomas, investigating differences in longitudinal effects between responders and non-responders
Abstract Introduction: Mogamulizumab (moga), an anti-CC chemokine receptor 4 (CCR4) antibody, is approved in Japan for CCR4+ adult T-cell le...
Characterisation of the megakaryocyte proteome in patients with Philadelphia negative myeloproliferative neoplasms
Abstract Introduction: Megakaryocytes are considered to drive pathology in the classical Philadelphia-negative myeloproliferative neoplasms...
Trends and disparities in premature mortality from hematologic malignancies: Analysis of CDC wonder data, 1999-2020
Abstract Background: Premature mortality from hematologic malignancies represents a major source of life-years lost, and trends and disparit...
Ponatinib-based combination therapies including asciminib and venetoclax were effective on patient-derived xenograft models of chronic myeloid leukemia in blast Phase
Abstract Introduction:Blast phase of chronic myeloid leukemia (CML-BP) represents advanced and aggressive phase of CML, marked by high genet...
Venetoclax retreatment of real-world patients with chronic lymphocytic leukemia previously treated with venetoclax-based regimens
Abstract BACKGROUND Venetoclax (Ven) has notable therapeutic potential in the treatment of chronic lymphocytic leukemia (CLL). As a result of...
Sonar-AI discovers first comprehensively described cases of GLP-1 receptor agonist associated thrombocytopenia: Faster, cheaper, and better than the 20th century approach of RADAR/sonar
Abstract Background/Introduction. The 21st century Southern Network on Adverse Reactions-Artificial Intelligence (SONAR-AI) is a team of mul...
Lysyl oxidases directly control cell surface abundance of platelet-derived growth factor receptors and signaling in osteoblasts
Abstract Introduction Platelet-derived Growth Factor Receptors α and β (PDGFRs) are fundamental regulators of cell devel...
Standardizing VTE prophylaxis in the inpatient setting: A quality improvement project
Abstract Introduction: Venous thromboembolism (VTE) is a major preventable cause of morbidity and mortality in hospitalized patients. Pharma...
Efficacy and safety of iptacopan in paroxysmal nocturnal hemoglobinuria (PNH): A real-world study of 35 patients from anhui, China
Abstract Efficacy and Safety of Iptacopan in Paroxysmal Nocturnal Hemoglobinuria (PNH): A Multidimensional Analysis of 35 Patients Objective...
Etoposide +cytarabine plus G-CSF mitigates daratumumab-associated impairment on stem cell mobilization yields in multiple myeloma
Abstract Objective: Quadruplet induction therapy comprising daratumumab(dara) and lenalidomide(lena), followed by high-dose chemotherapy and...
Fusion-specific regulation of polyamine synthesis sensitizes to BCL-XL inhibition in TCF3::PBX1+ B-ALL
Abstract Fusion transcription factors (TF) are hallmark oncogenic drivers in pediatric B cell acute lymphoblastic leukemia (B-ALL), contribu...