Angewandte Chemie International Edition
Articles in this Issue
Operando Reconstruction of NiB Precatalyst Into Adaptive Heterointerfaces for CO <sub>2</sub> Photoreduction via Tandem Hydrogen Relay
ABSTRACT Photocatalytic CO 2 reduction is a transformative carbon neutrality technology, yet the electronic competition b...
Stability‐Enhanced Therapeutic Artificial Cells Based on a Lipid–Polymer Integrated Architecture
ABSTRACT Current artificial cells often lack robustness in the face of the complex physiological milieu. Additionally, the strategies for mimicking natural cargo...
Assembly of Bioactive Superstructures via Metal–Phenolic Complexation for Blood Purification
ABSTRACT Hyperbilirubinemia, which stems from bilirubin accumulation caused by liver failure, can lead to jaundice, multi‐organ damage, and mortality. Hemoperfus...
Orbital Engineering via Double‐Exchange Interaction in a Bimetallic MOF for Electrocatalytic C─S Coupling of CO <sub>2</sub> and Sulfate
ABSTRACT Guided by molecular orbital theory, we have designed and synthesized a novel bimetallic metal‐organic framework (BTC‐Co‐O‐Cu‐BTA) for the electrocatalyt...
Orthosteric Control of Acidity Through Sulfate Binding in a Neutral Cyclo[8]pyrrole
ABSTRACT Acid–base equilibria can be shifted when binding events alter the local electrostatic and hydrogen‐bonding environment of an ionizable site. Implementin...
Molecular‐Level Modulation of Mass Transfer Kinetics in Trinuclear Copper Cluster–Based COFs Enables Efficient Electrocatalytic Nitrate Reduction
ABSTRACT Electrocatalytic nitrate reduction (NO 3 RR) provides a sustainable route for ammonia synthesis while mitigating...
Orchestrating Reactive Intermediates: Unlocking Near‐Complete Oxidant Utilization in Electrochemical‐Thermal Cascade Oxime Synthesis
ABSTRACT Oxime synthesis via hydroxylamine is the preferred route and is conventionally achieved by ammoxidation of ammonia with hydrogen peroxide. Yet, in alkal...
Delocalization‐Driven Activation of Inert Imine Linkages in Covalent Organic Frameworks for Reversible Magnesium Storage
ABSTRACT Imine‐linked covalent organic frameworks (COFs) are promising cathodes for rechargeable magnesium batteries (RMBs), yet their abundant imine linkages (C...
Modulating Local Coordination in Single‐Atom Catalysts: From Fundamental Concepts to Emerging Breakthroughs in Electrocatalysis
ABSTRACT Single‐atom catalysts (SACs) have attracted significant interest due to their maximized atom efficiency, structural precision, and unique catalytic properties. While the cen...
Dynamic Fluorescence Visualization of Nonequilibrium Supramolecular Assembly Regulated by a Proton Reservoir
ABSTRACT Living systems sustain nonequilibrium supramolecular assemblies through continuous energy input and concomitant dissipation, with adenosine triphosphate (ATP) serving as a u...
Outside Front Cover: Uncovering Aggregation‐Induced Emission in Carbon Dots for Color‐Changing Hydrogels and Information Encryption
2‐CF <sub>2</sub> H(D)‐Imidazolium Salts: A Reagent Platform for Bis(Deuterio)Difluoromethylation of Alkenes Under Copper/Photoredox Dual Catalysis
ABSTRACT The difluoromethyl group (–CF 2 H) has emerged as a privileged motif in modern drug design due to its ability to...
Dynamic Heterovalent Dual‐Cu Sites for O═O Cleavage in Electrocatalytic Oxygen Reduction Reaction
ABSTRACT Activation and cleavage of the inert O═O bond represent a central challenge in energy electrochemistry. Here, the Cu dual‐atom catalyst (Cu‐DAC) is cons...
Shaping Water Adsorption and Desorption in Multivariate Metal–Organic Frameworks for Optimized Ultralow‐Temperature‐Driven Refrigeration
ABSTRACT Ultralow‐temperature‐driven water‐sorption refrigeration provides an energy‐saving and eco‐friendly solution to realize near‐zero‐carbon cooling applica...
A Polyzwitterionic “Ion‐Sponge” Interphase via In Situ Self‐Polymerization for Ultradurable Zinc Batteries
ABSTRACT Aqueous zinc batteries hold great potential for grid storage applications; however, their practical deployment is severely limited by parasitic side rea...
Host Dearomatization for Prolonging Room‐Temperature Phosphorescence
ABSTRACT Host–guest doping has emerged as a powerful platform for constructing organic room‐temperature phosphorescence (RTP) materials, owing to its structural tunability and facile...
Decouple H <sub>2</sub> O <sub>2</sub> Electrosynthesis From Microenvironmental Decomposition via Atomic Site Density Engineering
ABSTRACT Electrocatalytic H 2 O 2 production through two‐electron oxygen reductio...
Metallomacrocyclic Ligands Stabilized Icosahedral Superatomic Nanoclusters With NIR‐I to NIR‐II Phosphorescence Modulation
ABSTRACT Coinage metal nanoclusters with near‐infrared‐II (NIR‐II, λ PL > 1000 nm) photoluminescen...
Isotopic Engineering of Water Reactivity for Stable Aqueous Iron‐Metal Batteries
ABSTRACT The development of aqueous iron‐metal batteries (AIBs) is critically hindered by the severe parasitic hydrogen evolution reaction (HER) at the anodes an...
Silver‐Catalyzed Vinylogous C(sp <sup>3</sup> )–C(sp <sup>3</sup> ) Coupling of Bicyclo[1.1.0]Butanes With Vinylcarbenes
ABSTRACT Owing to the intrinsically high reactivity of the carbenoid center, the vinylogous reactivity of metallovinylcarbenes—specifically the selective constru...
Electronic‐Geometric Pre‐Compensation Enables Intermetallic RhSb Bimetallenes for Efficient Nitrite Electroreduction
ABSTRACT Sustainable electrochemical synthesis aims to produce high‐value chemicals under mild conditions, but its advancement is hindered by electrocatalyst dea...
Dynamic Bifunctional Sites on a COF Enable Efficient Immobilization and Conversion of Iodine Species Toward Li‐Iodine Batteries
ABSTRACT The thermodynamic instability of iodine cation (I + ) and shuttle effect of polyiodide in the two‐electron Li‐io...
Local Antiaromaticity‐Mediated Chiral Donor–Acceptor Strategy for Efficient Circularly Polarized Luminescence
ABSTRACT Achieving highly efficient circularly polarized luminescence in organic light‐emitting diodes remains a fundamental challenge, because conventional chir...
Light‐Induced Electron‐Rich Gold Directs Nitrate Reduction to Dinitrogen
ABSTRACT Electrocatalytic nitrate reduction reaction (NO 3 RR) provides a controllable route for nitrate conversion, whil...
Induced‐Fit for Oxygen Adsorption: Flexible Conjugated Microporous Polymers With Self‐Adaptive Active Sites for H <sub>2</sub> O <sub>2</sub> Photosynthesis
ABSTRACT Photocatalytic hydrogen peroxide (H 2 O 2 ) synthesis via oxygen reducti...