Angewandte Chemie International Edition
Articles in this Issue
Interfacial Charge‐Transfer Kinetics Regulate Na <sub>2</sub> S Deposition by Recycled V Single‐Atom Catalysts for Durable Na–S Batteries
ABSTRACT Na 2 S, as the terminal discharge product of room‐temperature sodium–sulfur (Na–S) batteries, is electronically...
Multidimensional Exploration of Platinum Complexes for Cancer Therapy
ABSTRACT Platinum complexes play an important role in contemporary cancer therapy. The rational design of modern anticancer platinum complexes is largely based on the hallmarks of ca...
Conformation‐Guided Disulfide Pairing Enables Efficient Folding of Disulfide‐Rich Peptides
ABSTRACT Disulfide bond formation is critical for the structural integrity and biological functions of peptides and proteins. For disulfide‐rich peptides (DRPs), particularly those c...
Electrocatalytic C–C Coupled Oligomerization From Biomass Molecules Through Pd Single‐Atom Interfacial Regulation
ABSTRACT Fossil‐derived diesel raises sustainability and air‐quality concerns, motivating biomass‐based alternatives; however, current biodiesel routes suffer fr...
Unsaturated Copper Sites for Selective Electroreduction of CO to Alcohol
ABSTRACT Electrochemical reduction reaction of carbon monoxide (CORR) has been extensively studied due to its high selectivity for producing multi‐carbon (C...
Adsorbate‐Induced Reversible Changes in Zeolite ZEO‐5 Attributed to Its Triple‐Four‐Silicate‐Rings
ABSTRACT Extra‐large pore zeolites exhibit structural features distinct from those of classical zeolites, with potential consequences in their use as adsorbents and catalysts. A low‐...
A General Design of Compact “Zero‐On” NIR‐II Photoacoustic Dyes for High‐Fidelity Imaging
ABSTRACT Near‐infrared‐II (1000–1700 nm) photoacoustic imaging enables deep‐tissue visualization with high spatial precision but lacks organic probes integrating...
Efficient Utilization of Solar Energy Mediated by Singlet Fission Passage to Boost Photocatalytic Hydrogen Production
ABSTRACT Building efficient channels for capturing and utilizing light energy is the key to achieving sustainable utilization of solar energy, so as to enhance t...
On‐Demand Deconstructable Thermosets Through Cleavable Comonomer and Thermolatent Base Synergy
ABSTRACT Thermosets provide superior chemical and mechanical properties critical for high‐performance applications, but their permanent crosslinked networks seve...
Bioorthogonal Tools for Ethanolamine Lipids and Protein Conjugates
ABSTRACT Phosphatidylethanolamine (PE) is the second most abundant class of phospholipids in eukaryotic membranes, as well as a precursor for essential posttranslational protein modi...
Decoupling TM–O Antibonding via Targeted Orbital Engineering Enables High‐Voltage and Long‐Life Sodium Polyanionic Cathodes
ABSTRACT Polyanionic cathode materials based on Mn/V redox couples offer high‐voltage plateaux and high theoretical energy density for sodium‐ion batteries (SIBs...
Backbone Steric Constraints Underlie High Passive Membrane Permeability of <i>N</i> ‐Alkyl Peptides
ABSTRACT N ‐Alkyl peptides have emerged as promising drug modalities, yet the structural determinants governing passive membrane permeability...
Interfacial Raft‐Like Structures From Bottlebrush Polymers
ABSTRACT We investigated the interfacial behavior of amphiphilic random copolymer‐grafted bottlebrush polymers (RC‐BBPs) synthesized by copper‐catalyzed azide–alkyne cycloaddition in...
Single‐Atom Control of Aromaticity and Excited‐State Dynamics in Endohedral Zirconium–Antimony Zintl Clusters
ABSTRACT Three‐dimensional (3D) aromaticity provides a powerful framework for understanding the stability and electronic structures of superatomic clusters, yet...
Adaptive Hydrogenation of Alkynes Using CO as a Molecular Trigger to Selectively Produce Alkanes or <i>Z</i> ‐Alkenes
ABSTRACT The selective hydrogenation of alkynes to either alkanes or alkenes is an important step in synthetic processes across the entire chemical value chain w...
Unraveling A4GALT Mechanism and Its Modulation With Adamantyl‐Galactosylceramide Analogues: Advancing Fabry Disease Therapeutic Strategies
ABSTRACT Fabry disease (FD), one of the most prevalent lysosomal storage disorders in Europe, is caused by mutations in the GLA...
Topological Densification‐Reinforced Robust and Durable Protein Adhesive at Dynamic Interfaces
ABSTRACT Robust and durable adhesion is essential for effective tissue sealing and rapid hemostasis in modern clinical practice. However, most two‐component biomimetic systems often...
Inner Helmholtz Plane Reconstruction Enables High‑Voltage Sodium‑Ion Batteries
ABSTRACT Parasitic reactions at the cathode–electrolyte interface are the primary cause of rapid capacity fading in sodium‐ion batteries (SIBs) under high voltag...
Halogen Bonding as a Molecular Recognition Strategy for Genetic Code Expansion
ABSTRACT Aminoacyl‐tRNA synthetases (aaRSs) catalyze the attachment of amino acids (AAs) to their cognate tRNAs during protein synthesis. As aaRSs possess highly...
Decoupling Bidirectional Photochemical Degradation via Radical Scavenging for Stable Inverted Perovskite Solar Cells
ABSTRACT Interfacial instability between perovskite absorbers and fullerene‐based electron transport layers critically limits the operational stability of inverted perovskite solar c...
Dynamic Disulfide‐Linked Dimeric Acceptors for High‐Efficiency and Mechanically Robust Organic Solar Cells
ABSTRACT The practical application of organic solar cells (OSCs) in wearable electronics requires simultaneous improvements in efficiency, stability, and mechani...
One‐Step Synthesis of Sequence‐Tailored Amphiphilic Block Copolymers at the Emulsion Interface
ABSTRACT The synthesis of sequence‐controlled block copolymers (BCPs) via one‐step copolymerization has garnered significant interest, as it offers a highly acce...
Supramolecular Protection–Deprotection for Switching Pore‐Surface Functionality in a Crystalline Porous Organic Salt
ABSTRACT The precise installation of highly interactive functional groups on pore surfaces remains a central challenge in crystalline porous materials since such...
Dual‐Domain Coupling‐Driven Interface Remodeling Enables Ultra‐Dilute Flame‐Retardant Electrolytes for High‐Voltage, Wide‐Temperature Batteries
ABSTRACT The paradigm shift in electrolyte research is a critical driver for performance breakthroughs in sustainable batteries under extreme conditions. Ultra‐d...
Supramolecular Strategies for Modulating Excited‐State Properties of Photosensitizers in Photodynamic Therapy
ABSTRACT The performance of photosensitizers (PSs) in photodynamic therapy (PDT) is determined not only by their intrinsic molecular structures but also by their spatial organization...