Angewandte Chemie International Edition
Articles in this Issue
Making Commodity Polymers SuFExable: A Versatile Platform by Bridging SuFEx Click Chemistry and Photo‐Modification
ABSTRACT A central challenge in polymer development lies in the dilemma between the inherent limitations of each polymer and the diverse requirements for material properties and func...
Synthesis of Chonemorphol A, Chonemorphol C, and Ecdysantheroside A Aglycone From Simple Steroids
ABSTRACT High‐oxidation‐state steroids, often with appealing medicinal value, are challenging synthetic targets. Introducing the desired oxidation states is ofte...
Inversed Cation Size Effects on Methanol Formations From CO <sub>2</sub> Electroreduction by Immobilized Cobalt Phthalocyanine
ABSTRACT The electrocatalytic reduction of CO 2 to methanol offers a compelling pathway for sustainable fuel synthesis, w...
Near‐100% Selective Photocatalytic Methane‐to‐Methanol Conversion Enabled by Synergistic Chlorine Radicals and Oxygen Vacancies
ABSTRACT The selective photocatalytic conversion of methane to a single product is a grand challenge, primarily due to uncontrollable over‐oxidation and ineffici...
Outside Front Cover: Toward Multi(radio)Metalated DNA: Enzymatic Polymerization of Metal‐Chelate‐Modified Deoxyribonucleoside Triphosphates (Angew. Chem. Int. Ed. 27/2026)
Nanoscale Spatial Engineering of Ligands Using DNA Origami for Precise Modulation of Membrane Receptor Signaling
ABSTRACT Dimerization or multimerization of surface membrane receptors is essential for transmitting extracellular recognition events across the plasma membrane, triggering intracell...
A Crystalline (Amino)(chloro)Carbene: A Platform for Nucleophilic Substitution at a Carbene Center
ABSTRACT Halogenocarbenes have attracted significant interest for almost a century because they combine classical singlet carbene reactivity with the presence of a readily substitute...
A De Novo Chemoenzymatic Assembly Strategy Enables the Efficient Preparation of a Large Core‐Xylosylated N‐Glycan Library for Probing Antibodies Against <i>Schistosoma japonicum</i>
ABSTRACT Core‐xylosylated N‐glycans represent a ubiquitous class of N‐glycans widely distributed across nature. Recently, core‐xylosylated N‐glycans have attract...
A Neutral “Masked” Diborene and Its Reactivity Toward Metal‐Free Pyridine Homocoupling
ABSTRACT An unprecedented neutral “masked” non‐external‐donor‐stabilized diborene is generated via intramolecular arene dearomatization of an N‐heterocyclic imin...
Multichannel Through‐Space Charge Transfer Triplet Photosensitizers for Rapid Visible‐Light Polymerization and High‐Fidelity 3D Printing
ABSTRACT Visible‐light‐driven polymerization offers unparalleled spatiotemporal control and energy efficiency, yet its practical performance is fundamentally con...
Inside Back Cover: The Role of Shape Commensurability in Chirality Transfer: Gold Nanoshape Solutes in a Discotic Nematic Liquid Crystal Solvent (Angew. Chem. Int. Ed. 27/2026)
Nanographene‐Based van der Waals Organic Framework With Permanent Porosity
ABSTRACT Porous crystalline materials traditionally rely on robust coordination or covalent bonds. Herein, we report a new C...
Integration of Fe Single Atoms to Improve Kinetics and Mass Transport in Oxygen Reduction Reaction for Zinc‐Air Batteries
ABSTRACT Simultaneous optimization of intrinsic activity and mass transport to enhance the oxygen reduction reaction (ORR) performance of zinc‐air battery (ZAB)...
Strongly Correlated Electron Systems in Triple Metal Atoms Trigger Atomic‐Level Structure Resonance for Durable and Efficient Ammonia Electrosynthesis
ABSTRACT Electrocatalytic nitrate reduction reaction (NO 3 RR) is an important route for achieving both sustainable ammon...
Revitalizing Fulleropyrrolidine via Nonionic Sidechain Engineering: An Ethanol‐Processible Interlayer Enabling Efficient Organic Solar Cells
ABSTRACT Organic solar cells (OSCs) advancement hinges critically on cathode interlayer materials (CIMs) that meet multiple requirements: thickness‐insensitivity...
Intermolecular Interactions Regulating Exciton Behavior in Hydrogen‐Bonded Organic Framework for Photocatalytic Aerobic Oxidation
ABSTRACT Exciton effects play a vital role in photocatalytic reactions, yet their precise regulation remains highly challenging, as even subtle variations can le...
Zexin Jin
Cascade Reaction for Efficient <sup>1</sup> O <sub>2</sub> Generation Enabled by Spatially Coupled Vacancy Pairs
ABSTRACT Singlet oxygen ( 1 O 2 ) is a powerful nonradical oxidant for water puri...
Total Synthesis of Allocyclinone A via Late‐Stage Halogen Swapping
ABSTRACT Allocyclinones A–D are small congeners of angucyclinones with several unusual structural features and potent antibiotic activity against various Gram‐positive pathogens. All...
Dual‐Channel Interdigitated Aptamer‐Based Sensors for Rapid Small‐Molecule Detection in Biofluids
ABSTRACT Timely and decentralized quantification of small‐molecule biomarkers is essential for point‐of‐care (POC) diagnostics, but their reliable detection in biofluids remains chal...
Visible‐Light Unlocked Carbene Insertion and Radical Release in a Structurally Constrained Pincer Phosphorus Compound
ABSTRACT Geometrically constrained phosphines have attracted significant attention for their ability to mediate reactions traditionally associated with transition metals. Here, we sh...
The Role of Shape Commensurability in Chirality Transfer: Gold Nanoshape Solutes in a Discotic Nematic Liquid Crystal Solvent
ABSTRACT Chirality, as an inherently geometric concept, is well understood at most length scales and is a principal attribute of objects and figures. Quantitativ...
Synergistic Lewis Acid Photocatalysis Over Cluster‐Defect‐Engineered UiO‐66 for Efficient Liquid Biomass Upgrading
ABSTRACT Defect engineering provides new opportunities to overcome the intrinsic limitations of metal–organic frameworks (MOFs) in photocatalysis. Herein, a clus...
Crystal Engineering of Intrinsic Dynamicity in Metal‐Organic Frameworks for Adaptive Multicomponent Catalysis
ABSTRACT Metal‐organic frameworks (MOFs) provide unique catalytic environments through steric confinement imposed by their pores that govern reactivity, but conc...
Cyclo‐Polyproline: Chameleonic All‐Peptide Macrocycles With Induced‐Fit Host‐Guest Recognition
ABSTRACT We report the design, synthesis, and characterization of a novel class of all‐peptide macrocycles, Cyclo‐Polyprolines ( CP...