Angewandte Chemie International Edition
Articles in this Issue
Electrochemical Assembly of a Defective Cu Catalyst for High Current CO <sub>2</sub> Electrolysis to Methane in a Zero‐Gap Electrolyzer
Abstract CO 2 electrolysis to methane offers a promising route toward enabling long‐term storage of renewable energy. How...
Electrochemical Late‐Stage Stitching of Tryptophan Peptides via N─S Bond Formation
Abstract Late‐stage diversification of peptides via selective modification of endogenous amino acid side chains provides a powerful strategy to access analogues with enhanced bioacti...
In Situ Construction of NaF‐rich Solid Electrolyte Interphase with Metallic Ce Sites for Stable Anode‐Free Sodium Metal Batteries
Abstract Developing reversible Na plating/stripping under high depth of discharge (DOD) is critical for stable anode‐free sodium metal batteries (AFSMBs). Achiev...
Dual‐Ligand Regulation of Homogeneous Cation–Anion Distribution Enables Efficient and Stable Perovskite Solar Cells
Abstract While amidine ligands are known to significantly enhance defect passivation in perovskite solar cells (PSCs), their role in modulating perovskite film h...
Lithium Iodide Enables Bis‐electrophilic Ring‐Opening of Azabicyclo[1.1.0]butanes
Abstract Azetidines are privileged nitrogen heterocycles in medicinal chemistry; however, current synthetic methodologies utilizing azabicyclo[1.1.0]butanes (ABBs) predominantly rely...
Tubular All‐Benzene Nanocarbon with Evolving Excited‐State Chirality
Abstract Molecular nanocarbons with precisely defined conjugated scaffolds can provide an ideal platform for investigating mechanistic insights into photophysica...
Corrosion‐Driven Ni <sub>3</sub> S <sub>4</sub> Gradient in NiFe‐LDH Enables Durable Industrial‐Scale Water Electrolysis
Abstract Designing low‐cost yet highly efficient oxygen evolution reaction (OER) electrocatalysts is essential to enable sustainable green hydrogen generation. H...
Synergistic Enhancement of Electron and Hole Transport by Pd Single Atoms and Gradient‐Distributed Ti <sup>3+</sup> Species for High‐Performance Photocatalytic Oxidation of CH <sub>4</sub> to Oxygenates
Abstract Photocatalytic oxidation of methane to liquid oxygenates offers a sustainable strategy for utilizing natural gas and reducing carbon emissions. However,...
Organic‐Acid‐Mediated Growth of Oriented Membrane from 2D‐Structured Zirconium MOF for CO <sub>2</sub> Separation
Abstract Two‐dimensional structured metal–organic framework (2D‐structured MOF) membranes with functionalized and ordered‐direction pores hold significant promis...
Mechanism of the Stoltz–Grubbs (KO <i> <sup>t</sup> </i> Bu/Et <sub>3</sub> SiH) Silylation: Single‐Electron Transfer is the Missing Link between the Heterolytic and Radical Pathways
Abstract A new mechanism for the Stoltz–Grubbs (KO t Bu/Et...
Synthesis, Structures, and CPL Property of Inner‐Wall Modified Pagoda[5]Arenes Driven by Cavity Microenvironment
Abstract Macrocyclic arenes with large cavities and chirality are attractive in supramolecular chemistry, but fixing their conformation and obtaining stable chir...
A Novel Antimalarial Agent that Inhibits Protein Synthesis in <i>Plasmodium falciparum</i>
Abstract The emergence of drug resistance to nearly all antimalarials following their rollout underscores the need for novel chemotypes with novel modes of actio...
Intergrowth of Prismatic and Octahedral Layers to Inhibit Fe Migration in Oxide Cathodes for Sodium‐Ion Batteries
Abstract Fe‐based layered oxides have emerged as promising sustainable cathode materials for sodium‐ion batteries (SIBs) due to their earth abundance. However, t...
Adaptive Rhodium Catalysis with a Lewis‑Acidic Secondary Sphere for Divergent Hydrogenation of Propargylic Alcohols
Abstract Achieving chemoselective transformations of multifunctional molecules under mild and sustainable conditions remains a central challenge in catalysis. He...
Discovery of a Serine‐Directed Chemical Reaction for Site‐Specific Protein Modification via Phage Display Screening
Abstract Conventional biocompatible chemistry typically depends on unnatural functional groups, such as alkynes and azides. Here, we present a natural amino acid...
Capturing the Complexities of Catalyst–Support Interactions with the Help of Machine Learning
Abstract The structure of metal nanoparticles is central to their catalytic activity, but metal–support interactions are difficult to model via quantum‐mechanical calculations. Using...
From Lignocellulose to Sustainable Aviation Fuel: Innovative Synthesis through Friedel–Crafts Alkylation and Hydrodeoxygenation
Abstract To address the aviation sector's growing carbon footprint, this study presents a novel route for producing sustainable aviation fuel precursors via acid‐catalyzed Friedel–Cr...
Identification of a Proteolysis‐Targeting‐Chimera that Addresses Activated Checkpoint Kinase‐1 Reveals its Non‐Catalytic Functions in Tumor Cells
Abstract Checkpoint kinase‐1 (CHK1) controls DNA replication and repair. Tumor cells depend on CHK1, whose high levels are associated with worse patient prognosis. We define a bona f...
Iridium Photosensitizers Immobilized on Metal–Organic Layers Lead to Enhanced Enantioselectivity in Ni/Ir Dual Photocatalysis
Abstract The Ir/Ni dual‐catalytic system plays a crucial role in asymmetric photocatalysis for synthesizing enantioenriched compounds. However, challenges such a...
Hydrogen Affinity in Intermetallic Electrides as a Key Indicator of Catalytic Performance in Ammonia Synthesis
Abstract Electrides have emerged as promising catalysts or catalyst supports for efficient ammonia synthesis under mild conditions. ATmSi compounds (A = rare ear...
Panchromatic Gold Alkynyl Complexes with Pyrenyl <i>‐N</i> ‐Heterocyclic Carbene Ligand Displaying Anti‐Kasha Behavior
Abstract A unique family of alkynyl‐gold(I)‐complexes ( 1 – 6 ) containing pyreny...
Frontispiece: Panchromatic Gold Alkynyl Complexes with Pyrenyl <i>‐N</i> ‐Heterocyclic Carbene Ligand Displaying Anti‐Kasha Behavior
Discovery of a Cryptic Pocket in <i>Ec</i> DsbA Opens New Opportunities for Antibacterial Discovery
Abstract We have used nuclear magnetic resonance (NMR) spectroscopy to characterize dynamics in the bacterial oxidoreductase enzyme Escherich...
Light‐Controlled Reconfigurable Optical Structures Using Photomechanical Organic Crystals
Abstract In crystal form, 4‐fluoro‐9‐anthracenecarboxylic acid ( 4F‐9AC ) undergoes a room temperature reversible intermo...
Design of Cryogenic Electrolyte with Organic‐Free Solvation Structure for Wide‐Temperature Zinc Metal Batteries
Abstract Albeit the promising performance at ambient temperatures, the development of zinc metal batteries (ZMBs) is still haunted by the freezing‐prone characte...