Angewandte Chemie International Edition
Articles in this Issue
Pd‐Catalyzed Enantioselective Construction of Isoindolo[2,1‐ <i>a</i> ]indoles
ABSTRACT Isoindolo[2,1‐ a ]indoles are a class of important functionalized indole‐based heterocycles with significant uti...
Palladium‐Catalyzed Asymmetric Synthesis of Methylidene Cyclobutanes via Enantioselective Intramolecular Heck‐Type Reactions
ABSTRACT Cyclobutanes as well as 2‐substituted alkylidene cyclobutanes (ADCBs) are important skeletons in pharmaceuticals and versatile precursors in organic synthesis. However, enan...
A Bimetallic Covalent Organic Framework Photonic Synaptic Electrocatalysts
ABSTRACT Photonic synaptic electrocatalysts encode catalytic activity as a writable, retainable state under optical stimulation, enabling history‐dependent performance modulation wit...
Scalable ω‐Substituted α‐Olefins via Living Chain Transfer Telomerization: A Platform for Next Generation Polyolefins
ABSTRACT Isomerically pure, ω‐substituted α‐olefins of general structure, X‐(CH 2 ) m...
Solvent‐Driven Modulation of Covalent‐Organic Framework Nano‐Architectures for Photothermal‐Catalytic Biomass Valorization and Hydrogen Peroxide Production
ABSTRACT The modulation of three‐dimensional (3D) covalent‐organic frameworks (COFs) into multifunctional nano‐architectures is highly desirable for their extended applications yet s...
Fluorescent cAMP Analogs: Enzymatic Synthesis, Unexpected Photophysical Behavior and Protein Kinase A Recognition
ABSTRACT Cyclic adenosine monophosphate (cAMP) is a second messenger, regulating critical physiological processes. We report the enzymatic synthesis, unique phot...
Synergistic Bulk‐Surface Modulation Stabilizing LiCoO <sub>2</sub> at 4.65 V via Zr‐Pillaring and In Situ Lattice‐Matching Engineering
ABSTRACT Lithium cobalt oxide (LiCoO 2 , LCO) is a critical cathode material for high‐energy‐density lithium‐ion batterie...
Modulated Structure‐Electronic Coupling at Pt/CeO <sub>x</sub> –TiO <sub>2</sub> Interfaces Boosts Low‐Temperature Preferential CO Oxidation
ABSTRACT Preferential oxidation, PROX, of residual CO in a hydrogen‐rich synthetic gas is the final stage of industrial hydrogen production and purification. How...
Surface Hydroxyl Steered Adsorption Configuration for Efficient Photocatalysis Coupling Hydrogen Evolution and 5‐Hydroxymethylfurfural Selective Oxidation Toward 2,5‐Furandicarboxylic Acid Production
ABSTRACT Photocatalytic coupling water reduction reaction and 5‐hydroxymethylfurfural (HMF) selective oxidation toward 2,5‐furandicarboxylic acid (FDCA) offers a...
Stereoelectronically Controlled Regioselective Allylation of Aldehyde Under Photoredox/Chromium Catalysis
ABSTRACT The formation of structurally defined α,γ‐disubstituted allylmetallic intermediate which could undergo regioselective allylation with carbonyl compounds remains a formidable...
Imide Cyclophane Assemblies Enable Aquaporin‐Like Water Transport
ABSTRACT Artificial water channels (AWCs) that replicate the high efficiency and selectivity of natural aquaporins are of considerable interest for desalination,...
Tenfold Expansion Submicrometer MALDI Mass Spectrometry Imaging of Tissues and Cultured Cells
ABSTRACT Achieving submicrometer lateral resolution in matrix‐assisted laser desorption/ionization mass spectrometry imaging (MALDI‐MSI) is essential for molecular characterization...
Programmable Nanostructural Orientation on Amorphous Phase‐Separating Systems
ABSTRACT Currently, there remains a lack of broadly applicable strategies for programming the nanostructural orientation in a bottom‐up way (e.g., for those widely used amorphous pha...
External‐Field‐Enhanced Helmholtz‐Layer Local Charge Density Enables C─C Coupling in Pure‐H <sub>2</sub> O‐Fed CO <sub>2</sub> Electroreduction To C <sub>2+</sub> Products
ABSTRACT Electrochemical CO 2 reduction (ECO 2 R) is a promising decarbonization...
Photochemical Reaction Discovery Enabled by the Dynamic Speciation of Copper Complexes
ABSTRACT Rapid access to molecules with tailored function is essential to advancing the discovery of new medicines, materials, and agrochemicals. Chemical reacti...
Correction to “Control of Tetrazine Bioorthogonal Reactivity by Rotaxanation”
Crystal Void Fraction‐Engineered Fe‐S Catalysts for Self‐Sustaining Li‐CO <sub>2</sub> Mars Batteries
ABSTRACT Efficient energy storage is vital for self‐sustaining Martian exploration. Li‐CO 2 batteries are promising by ut...
Lateral‐Site Unblocking Enables Bilateral <i>π</i> ‐Chromophore Organization for Giant Birefringence in One‐Dimensional Lead Hybrids
ABSTRACT Birefringence in low‐dimensional organic–inorganic hybrids depends on both the intrinsic anisotropy of building units and their dense, coherent lattice...
Regioselective Migratory Ring Expansion of Heterole‐Fused Norcaradienes for Modular Access to Azulene‐Incorporated Thienoacenes
ABSTRACT In this study, we report a sterically steered, thermally driven [1,5]‐C shift (“carbon‐walking”) of congested heterole‐fused norcaradienes (NCDs), generated in situ by tetra...
Rational Molecular Design to Improve Digital Polymer Readout in Aerolysin‐Based Nanopore Sequencing
ABSTRACT Nanopore sequencing is a promising method for decoding synthetic digital polymers, but translocation signals are often complex. This study examines the influence of macromol...
Single‐Crystal Covalent Organic Frameworks for Anhydrous Proton Conduction Above 200°C
ABSTRACT The development of fast proton‐conducting materials that operate above 150°C with high chemical stability is both challenging and critically important f...
Recycling <sup>99</sup> Tc From Nuclear Wastewater by Coupling Photocatalysis and In Situ Ion‐Exchange on Bifunctional K‐SnS/TiO <sub>2</sub> Heterojunction
ABSTRACT The sustainable management of radionuclides in nuclear wastewater, typically like 99 TcO 4...
Nitrogen Speciation Dictates Industrial‐Current Oxygen Reduction in Metal‐Free Macrocycles for H <sub>2</sub> O <sub>2</sub> Synthesis
ABSTRACT Oxygen activation is a cornerstone of sustainable electrosynthesis, yet controlling reactive intermediates without metallic centers remains challenging...
Biomimetic Synthesis of Multinuclear Metal‐Oxo Bridges Under Mild Aqueous Conditions for Catalytic Cancer Therapy
ABSTRACT In biological systems, enzymes achieve efficient catalysis by precisely assembling multinuclear metal‐oxo bridges, such as Fe─O─Fe motifs, under physiological conditions. Ho...
Phase‐Inversion Engineering of Covalent Organic Framework Microspheres for Advanced Water Purification
ABSTRACT Covalent organic frameworks (COFs) are porous, crystalline polymers with broad application prospects. However, their microcrystalline powder morphology severely limits their...