Angewandte Chemie International Edition
Articles in this Issue
Proton‐Tautomerism Drives Redistribution of Electron Cloud Density in Covalent Organic Framework for Efficient Sodium‐Ion Storage
ABSTRACT Proton tautomerism, a ubiquitous phenomenon involving the dynamic interconversion of structural isomers through proton migration, has seldom been utiliz...
A Cell‐Resolved Ultrastable Biosensor Enables One‐Step Detection of Gene‐Fusion Transcripts in Unprocessed Whole Blood
ABSTRACT Cell‐specific detection of aberrant mRNA in blood is essential for diagnosing and treating hematological malignancies. However, current sensors are unable to function in unp...
Highly Selective Methane‐to‐Methanol Conversion Enabled by Bimetallic Nanoclusters Using Molecular Oxygen
ABSTRACT Methane, the most stable alkane, is significantly more stable than its partial oxidation products. This renders the highly selective conversion of CH...
Solvent Anchored Electrolytes for Lithium‐Ion Batteries Working at High Voltage and Wide Temperature
ABSTRACT Lithium‐ion batteries (LIBs) suffer from severe performance fading under coupled conditions of high voltage and wide temperature because cold retards Li...
Achieving Multimodal Trainable Self‐Strengthening Elastomers Through Mechano‐Oxidative Synergistic Induced Crosslinking
ABSTRACT Mechanically induced radical crosslinking strategies for material self‐strengthening have been widely applied in soft robotics and impact protection. However, this mechanism...
Long‐Lived Luminescence Over an Ultra‐Broad Temperature Range via Sequential Exciplex and Chemiluminescence Pathways
ABSTRACT Persistent luminescent polymers have recently attracted significant research interest due to their tunable afterglow properties and flexible molecular design. However, these...
Surface Polarity Reinforced Radicals Mediated C─N Coupling Towards Photoelectrochemical Synthesis of Energetic Nitro Compounds
ABSTRACT The direct synthesis of nitroaromatics from waste nitrogen sources represents a longstanding challenge in organic electrosynthesis, as prevailing hetero...
Converting 1,1‐Bisborylalkanes into 1,2‐Bisborylalkanes Enabled by Iron Ligand‐to‐Metal Charge Transfer (LMCT) Photocatalysis
ABSTRACT We report herein a strategy to convert 1,1‐bisborylalkanes into 1,2‐bisborylalkanes through iron ligand‐to‐metal charge transfer (LMCT) photocatalysis. Under the optimized c...
Solvent‐Induced Covalent Bond Softening Boosts Battery Voltage
ABSTRACT Increasing cell voltage is a key strategy for enhancing the energy density of lithium batteries. Previously, this was mainly achieved by adjusting the r...
Interfacial Energetics Reconstruction via Bridging Engineering for Efficient Inverted Perovskite Solar Cells and Modules
ABSTRACT Energy losses at perovskite/C 60 interface, stemming from energetic mismatch due to suboptimal interfacial conta...
Palladium/Photoredox‐Catalyzed Three‐Component Coupling for Glycoconjugation
ABSTRACT Glycoconjugation—the installation of sugar moieties onto molecular targets—represents a powerful strategy for modulating biological functions, yet the i...
High‐Performance Artificial Lithium Channel Enabled by a Brominated Organic Imine Cage
ABSTRACT Despite extensive advancements in the design of artificial transporters for K + , Cl −...
Mechanism Reevaluation and Reaction Development in Rhodium‐Catalyzed Cycloaddition of <i>gem</i> ‐Difluorinated Cyclopropanes
ABSTRACT Transition‐metal‐catalyzed cycloadditions of strained carbocycles have emerged as a powerful strategy for constructing complex molecular architectures t...
Control of Conformation and Spin for Programmable Singlet‐Triplet Exciton Balance in Through‐Space Charge‐Transfer Emitters
ABSTRACT Achieving continuous and predictable control over singlet‐triplet exciton partitioning in solution remains challenging for organic molecules, partly bec...
Room‐Temperature Gas‐Phase CO <sub>2</sub> ‐to‐C <sub>3</sub> Coupling by a 4 <i>f</i> ‐Aromatic Cluster
ABSTRACT Room‐temperature conversion of CO 2 into value‐added multi‐carbon products (C 3...
Electrochemical Biomimetic Iron‐Catalyzed Benzylic C─H Bonds Hydroxylation
ABSTRACT Electrochemical synthesis has attracted considerable attention as a green synthetic technology in recent years, particularly in the domain of selective oxidation and reducti...
Robust Linkage‐Encoded Covalent Organic Framework Membranes Sustain Selective Ion Transport for Energy Harvesting From Concentrated Acids
ABSTRACT Achieving simultaneously high ion permselectivity and chemical robustness in concentrated electrolytes remains a central challenge for membrane‐based te...
Multi‐Color Flexible Electrochromic Device for Smart Anti‐Counterfeiting
ABSTRACT Information security is critically important. We propose a multilevel electrochromic display design for dynamic information encryption, enabled by Prussian blue, zinc, and p...
Spatial Detection of Microsphere Polystyrene Plastics and Molecular Remodeling within a Full‐Body Mouse with MALDI Trapped Ion Mobility Mass Spectrometry Imaging
ABSTRACT Polystyrene (PS), a widely used synthetic polymer, breaks into micro‐ and nanoscale particles that can enter the body and accumulate in tissues. Convent...
Two‐Dimensional Polymers as Modular Metal‐Free Solid‐State Catalysts for Efficient Sono‐Piezo‐Photocatalytic Hydrogen Peroxide Production
ABSTRACT Piezo‐photocatalysis synergistically integrates the features of piezocatalysis and photocatalysis, offering promising applications in environmental remediation, energy conve...
Intermolecular Electrophilic Germylation Using GeCl <sub>4</sub> and Al <sub>2</sub> Cl <sub>6</sub>
ABSTRACT Electrophilic aromatic substitution is a textbook transformation for the lighter Group 14 elements. In contrast to acylation, alkylation, and silylation...
Spiro‐Buckybowl‐Structured Hole‐Transporting Materials Toward High‐Efficiency and Stable p–i–n Perovskite Solar Cells
ABSTRACT In p–i–n structured perovskite solar cells (PSCs), uniform distribution of underlying hole‐transporting materials (HTMs) and its interfacial interaction...
Fused Ring Engineering Induced Topology Control in Covalent Organic Frameworks: Unlocking Promoted Photocatalytic H <sub>2</sub> O <sub>2</sub> Production and Selective Methane Oxidation
ABSTRACT Efficient solar‐to‐chemical energy conversion and the selective activation of methane remain grand challenges in artificial photosynthesis. Here, we rep...
Molecular Engineering of an Isomeric Raman Reporter Palette With Synergistic Multidimensional Enhancement for Point‐of‐Care SERS Screening of Respiratory Pathogens
ABSTRACT Surface‐enhanced Raman scattering (SERS) combines molecular‐specific fingerprints and signal amplification, making it ideally suited for multiplexed point‐of‐care (POC) diag...
Regulating Dynamic Solid Electrolyte Interfacial Evolution via α‐H Methyl Substitution Carboxylate Ester Electrolytes Toward 20 Ah Wide‐Temperature (−60°C∼70°C) Li‐Ion Pouch Cells
ABSTRACT High reactivity of the α‐H sites in carboxylates is the root cause of inert interfacial evolution, where the resultant solvent co‐intercalation and α‐H‐...