Angewandte Chemie International Edition
Articles in this Issue
Photocatalytic Anaerobic Conversion of <i>m</i> ‐Xylene to Xylenols With Co‐Production of Hydrogen
ABSTRACT Mild photocatalytic valorization of aromatic hydrocarbons is promising for phenolic synthesis, but reliance on oxidants (O 2...
Unveiling the Role of Hydroxyls on Catalyst Surface in CO <sub>2</sub> Hydrogenation Reaction
ABSTRACT Understanding and tailoring catalyst surface species is crucial for controlling reaction pathways and product selectivity. Herein, we demonstrate that t...
Machine‐Learning‐Enabled Rapid Evolution of Photoenzymes for the Asymmetric Synthesis of <i>gem</i> ‐Difluorophosphonates
ABSTRACT gem ‐Difluorophosphonates are pivotal structural motifs in pharmaceuticals and bioactive molecules. While photoenzymatic catalysis p...
Perylenocarbazole‐Based Polycyclic Aromatic Self‐Assembled Monolayers with Tailored Electrostatic Potentials for High‐Performance Organic and Perovskite Solar Cells
ABSTRACT The development of universal hole‐transporting layers for organic and perovskite solar cells (OSCs/PSCs) remains challenging due to the lack of molecular strategies that pre...
Reactivity‐Controlled Aluminum (III)‐Based Electrolyte Enables Year‐Long Stable Metal Anodes
ABSTRACT Traditional aluminum (Al) electrolytes are limited by the strong corrosivity and monovalent carriers ( e.g ., Al...
Harnessing the Reactivity of Sulfinate Salts With Cystine: An Umpolung Approach to Residue‐Specific Peptide Modification
ABSTRACT The first use of sulfinate salts for the late‐stage modification of peptidic disulfide bonds is reported. While the majority of cysteine‐based peptide modifications rely on...
A Wagner–Meerwein‐Like Rearrangement Generates a Vinyl Group in the Biosynthesis of the Polychlorinated Lipopeptides Fischerazoles
ABSTRACT The discovery of structurally unusual natural products is a major inspiration in the search for novel enzymatic transformations. In this study, we emplo...
Quantitative Active Hydrogen Modulation via Mastering Interfacial Water Over Single Rare Earth Atom on Copper for NO <sub>3</sub> <sup>−</sup> ‐to‐NH <sub>3</sub> Electroreduction
ABSTRACT Electrochemical nitrate reduction to ammonia offers a sustainable route for NH 3 synthesis, where active hydroge...
A G‐Quadruplex‐Activated Near‐Infrared Chemiluminescent Probe for In Situ Hepatic Imaging of the Hepatitis C Virus Genome
ABSTRACT Real‐time monitoring of viral replication is essential for infectious disease diagnosis and antiviral drug development. The G‐quadruplex (G4), a conserved regulatory element...
Divergent Synthesis of Möbius and Hückel N‐Heterocycloarenes From a Common Macrocyclic Backbone
ABSTRACT We report the divergent synthesis of a Möbius N‐heterocycloarene ( 1 ) and a Hückel N‐heterocycloarene (...
Twin‐Boundary Cu <sub>2</sub> ‐Pair Pockets Drive Spatial Proximity of Key Intermediates for Efficient Urea Electrosynthesis
ABSTRACT Electrocatalytic urea synthesis from carbon dioxide (CO 2 ) and nitrate (NO 3...
Direct Electrosynthesis of Glycolate From Carbon Dioxide
ABSTRACT Electrocatalytic carbon dioxide reduction reaction (CO 2 RR) is an attractive and green technology that can conv...
Harnessing the <i>β</i> ‐Silicon Effect for Radical Cyclopolymerization: Direct Access to Si‐Containing Cyclic Olefin Polymers
ABSTRACT Cyclic olefin polymers (COPs) are important functional materials with extensively studied properties and syntheses. By contrast, silicon‐containing cycl...
Probing Blended‐Additive‐Regulated Interface Chemistry Based on a Dynamic Competition Mechanism in Lithium Metal Batteries
ABSTRACT Engineering a durable electrode‐electrolyte interphase is critical for high‐voltage lithium metal batteries. A fundamental obstacle to this goal is the...
Sequential H <sub>2</sub> S‐Triggered Redox Relay Nanoprobes for Self‐Sustained Chem‐Illuminating Cascade Photodynamic Therapy
ABSTRACT Endogenous chemiluminescence offers a transformative approach to photodynamic therapy that circumvents the limited penetration of external light and ena...
Day‐Long Persistent Luminescence in Intrinsically Integrated Donor‐Acceptor Carbon Dots Enabled by Defect‐Mediated Charge Trapping
ABSTRACT Long‐persistent luminescence (LPL) materials capable of storing and releasing optical energy over extended timescales are highly desirable for next‐generation photonic techn...
Quantum Spin‐1/2 Rings Built From [2]Triangulene Molecular Units
ABSTRACT Quantum spin rings represent fundamental model systems that exhibit distinctive quantum phenomena arising from their periodic boundary conditions and en...
Diphenoquinone‐Based Covalent Organic Frameworks for Efficient H <sub>2</sub> O <sub>2</sub> Production via Photothermal Synergistic Catalysis
ABSTRACT Covalent organic frameworks (COFs) have recently attracted tremendous attention as advanced photocatalytic platforms for H 2...
Probing Into Asymmetric Dearomatizing Photocycloadditions of 2‐Naphthalene Derivatives With Alkenes: [2 + 2] and [4 + 2] Pathways
ABSTRACT Catalytic dearomative photocycloaddition stands as one of the most powerful strategies for constructing highly complex, three‐dimensional polycyclic sca...
Spatiotemporal Mapping of Field‐Driven Electron Spillover across ZnO Facets
ABSTRACT Efficient spatial separation of photogenerated charge carriers remains a formidable challenge in photocatalysis. Here, we employ in situ Kelvin probe fo...
Suppressing Interfacial‐Accelerated Degradation in Perovskite Solar Cells via Supramolecular Co‐Assembly
ABSTRACT Metal halide perovskites exhibit exceptional optoelectronic properties, but the perovskite/organic hole‐transport layer interface often accelerates device degradation under...
Stacking the Deck to Make Materials With Atypically Short Heterometallic <i>d</i> <sup>8</sup> M(II)···Au(III) Bonds
ABSTRACT The first Pt II ···Au III metallophilic interaction is reported in K...
Anode for Nanoparticles, Cathode for Alloy: A Dual‐Functional Electrochemical Strategy for Spent ITO Upcycling
ABSTRACT The production and disposal of indium tin oxide (ITO) targets are rapidly increasing with the expansion of cutting‐edge optoelectronic and display techn...
Molecular Lubricant Mitigates Self‐Assembled Monolayer Aggregation in Perovskite Photovoltaics
ABSTRACT Molecular aggregation in self‐assembled monolayers (SAMs) remains a critical bottleneck for inverted perovskite solar cells (PSCs), particularly at buri...
Au(III) Complexes as Pyroptosis Inducers by Targeting Mitochondrial DNA for Tumor Immunity
ABSTRACT Targeting mitochondrial DNA (mtDNA) to induce a highly inflammatory form of cell death, such as pyroptosis, represents a promising yet underexplored the...