Angewandte Chemie International Edition
Articles in this Issue
Unraveling Terminal Cobalt–Antimony Double Bond: Breaking New Ground in Heavy Pnictogen Multiple Bonds
ABSTRACT Terminal pnictinidene complexes featuring heavy group 15 elements (Sb, Bi) doubly bonded to transition metals remain exceptionally elusive compared to t...
Repression of Virulence in <i>Staphylococcus aureus</i> by 2‐Aminothiol‐Mediated Quorum Quenching
ABSTRACT We present a novel strategy for the inhibition of quorum sensing in Staphylococcus bacteria. Previous work has f...
Borylcyclopropanes: Synthetic Strategies and Applications
ABSTRACT The carbon–boron bond is among the most versatile functional groups in organic synthesis, and its installation within the strained cyclopropane framework generates borylcycl...
Regulating Hydrogen Bond Competition to Break Ultrawide‐Temperature (−70°C to 100°C) Limits for All‐Climate Zinc Batteries
ABSTRACT Hydrogel electrolytes endow aqueous zinc‐metal batteries with inherent safety and mechanical flexibility, rendering them compelling for wearable energy...
Induction and Stabilization of Peptide Alpha‐Helices on Silica Nanoparticles
ABSTRACT Stabilizing secondary structure elements is critical to controlling peptide and protein bioactivity, stability, and function. The α‐helix, central to molecular recognition a...
Proton Conduction in Stable, Crystalline, and Porous Hydrogen‐Bonded Metal–Organic Frameworks
ABSTRACT Hydrogen‐bonded metal–organic frameworks (HMOFs) represent a novel class of crystalline materials that integrate hydrogen bonds (HBs) and coordination b...
Sourav Sekhar Bera
Manipulating Conical Intersections via a Noncovalent Strategy for Enhanced Photothermal Conversion
ABSTRACT Organic photothermal materials (OPMs) utilize efficient nonradiative decay for photothermal conversion, with conical intersections (CIs) playing a cruci...
Molecular Engineering Boosts Photon‐Activated Immunotherapy for Prostate Cancer Through Concurrent Pyroptosis and cGAS‐STING Pathway Activation
ABSTRACT Prostate cancer therapy is often limited by metastasis, drug resistance, and systemic toxicity. Photodynamic immunotherapy (PDIT) offers a promising alt...
An Ultrasonic Electrolysis Strategy for Monomethylamine Synthesis From Nitrate and CO <sub>2</sub>
ABSTRACT Electrocatalytic C─N coupling offers a feasible route for sustainable synthesis of monomethylamine (MMA), yet it still suffers from poor C/N reactant co...
Fully Conjugated Pseudo‐3D Covalent Organic Frameworks With Accelerated Electron Transport for High‐Performance Lithium‐Ion Batteries
ABSTRACT Organic electrodes are promising candidates for sustainable lithium‐ion batteries due to their environmental friendliness and tunable architectures, yet...
A Self‐Reinforcing LipoTIDE Nanoplatform That Overcomes Lipid‐Buffering Ferroptosis Resistance for Enhanced Cancer Therapy
ABSTRACT Lipid metabolic rewiring is a hallmark of malignancy, allowing tumor cells to sequester fatty acids within lipid droplets (LDs) as a protective reservoi...
Synergistic Effect of Chirality and Symmetry Reduction Enables Metal‐Free Perovskite Single Crystal With Stable Self‐Driven X‐ray Detection
ABSTRACT Exploring chiral components to induce a significant bulk photovoltaic effect (BPVE) for pursuing controllable dark current and device stability represen...
Mapping Proton‐Coupled Electron Transfer With Real Space Coordinates
ABSTRACT Both electron transfer (ET) and proton transfer (PT) are common steps in energy conversion across chemistry and biology. Coupling of these two transfer events reduces the en...
Flash Production of High‐Purity V <sup>3.5+</sup> Electrolyte via Electron Beam‐Induced Radiolysis Under Ambient Conditions
ABSTRACT The quest for high‐performance vanadium redox flow batteries has long been hindered by the time‐consuming and impurity‐prone synthesis of mixed‐valence...
A Comprehensive <sup>19</sup> F NMR Framework for Fragment‐Based Drug Discovery: The Validated Screening Library OpenFL600 and Efficient Affinity Ranking by CSAR
ABSTRACT Small‐molecule drug discovery relies on the identification of initial chemical starting points, or screening hits, and their subsequent optimization for potency and selectiv...
A Hydrogen Bond‐Mediated Förster Resonance Energy Transfer (FRET) Glue Strategy for Long‐Lived Room‐Temperature Phosphorescence From Silver Clusters
ABSTRACT Luminescent coinage metal clusters (CMCs) hold great promise for bioimaging and optical applications, but long‐lived room‐temperature phosphorescence (R...
Host–Guest Mismatch Enables Selective Hydrogen Atom Transfer
ABSTRACT Endogenous binding of molecular guests inside cavities of their hosts has been routinely utilized in enzymatic and supramolecular catalysis. In contrast...
Electride Formation of (Ca <sub>1–</sub> <i> <sub>x</sub> </i> Sr <i> <sub>x</sub> </i> ) <sub>3</sub> CrN <sub>3</sub> Induced by Negative Chemical Pressure
ABSTRACT Electrides are materials in which electrons occupy interstitial sites and act as anions. Conventional strategies for stabilizing electrides have relied...
Tailoring Photochromism Beyond Human Eye Visibility: On/Off Switchable NIR Absorption in an Aluminosilicate
ABSTRACT Photochromic materials are able to change reversibly between two colors. The color change is triggered by ultraviolet radiation and reversed by white light and/or heating. I...
Triadic Sites Drive Tandem CO <sub>2</sub> ‐to‐Ethanol Conversion by Steering *CO Coverage and *COH Intermediate Formation
ABSTRACT Single metal‐coordinated nitrogen‐doped carbon (M 1 ‐NC) materials hold great promise for electrocatalytic CO...
Enantioselective Hydrosilylation of Diverse Allenes via Nickel Catalysis
ABSTRACT Enantioselective hydrosilylation of allenes remains a significant challenge with a limited scope due to the difficulties in controlling both regioselect...
Correction to “Concerted Harnessing of Interfacial Concentration Field and Electronic Field for Boosting Electrocatalytic Semi‐Hydrogenation of Alkynol”
Ion Transfer During Ionomer Contact Electrification: Binding Affinity Controls Charging
ABSTRACT Contact electrification occurs ubiquitously in nature, but the identity of charge carriers in most situations remains uncertain, with electrons, ions, or nanoscopic material...
Discovery of an Antiviral Electron Transfer Process to Create Catalytically Self‐Sufficient Viral Restriction Factors
ABSTRACT Engineering immune‐silent, catalytically self‐sufficient antiviral restriction factor enzymes (iCAREs) provides a proof‐of‐concept for developing autonomous enzymes for futu...