Angewandte Chemie International Edition
Articles in this Issue
Self‐Adapting Lattice Respiration Enabled by Crystal Design and <i>d</i> ‐ <i>p</i> Orbital Hybridization Toward Highly Stable Rechargeable Aluminum Batteries
Abstract Rechargeable aluminum batteries (RABs) are promising for large‐scale energy storage due to the appealing three‐electron transfer feature, low cost, and...
Correction to “Precisely Tuning Photothermal and Photodynamic Effects of Polymeric Nanoparticles by Controlled Copolymerization”
Photosensitizer Repositioning Affords an Enantiocomplementary Enzyme for [2 + 2]‐Cycloadditions
Abstract The combination of genetic code expansion and directed evolution has recently given rise to enantioselective photoenzymes for [2 + 2]‐cycloadditions of...
Inside Front Cover: Unlocking Dual Recycling in Photo‐Curable Polycyanurate Thermosets Derived from Bio‐Resources (Angew. Chem. Int. Ed. 35/2025)
Tuning Eley–Rideal Mechanism in Electrochemical Acetylene Semi‐Hydrogenation
Abstract The Eley–Rideal (ER) mechanism is pivotal in heterogeneous catalysis processes such as fuel cells and electrolyzers, which rely heavily on the interacti...
Outside Front Cover: Thermodynamics of Water Displacement from Binding Sites and its Contributions to Supramolecular and Biomolecular Affinity (Angew. Chem. Int. Ed. 35/2025)
Is the Smallest Molecular Trefoil Knot Actually the Tightest One?
Abstract Tightness engineering has evolved as an efficient strategy for the design of knotted, woven, and entangled molecules and materials with desired properties and functions sinc...
PyBOX‐Integrated Chiral Covalent Organic Frameworks
Abstract Heterogeneous catalysts based on chiral covalent organic frameworks (CCOFs) are the new sensation in asymmetric catalysis. The pyridine‐bis(oxazoline) (...
Deciphering Tryptophan Oxygenation: Key Modulators of 2‐Oxindole Formation in MarE
Abstract MarE, a heme‐dependent aromatic oxygenase with a histidyl axial ligation, catalyzes the monooxygenation of β‐methyl‐ l...
Probing Multilevel Chiroptical Activity in Organic Supramolecular Microcrystals for High‐Performance Circularly Polarized Lasing
Abstract Chiral organic materials are rapidly emerging as a promising platform for circularly polarized lasing. However, the lag in mechanistic research has severely hindered the dev...
Design of Fluorine‐Free Weakly Coordinating Electrolyte Solvents with Enhanced Oxidative Stability
Abstract High concentrations of conducting salt in electrolyte formulations enhance the agglomeration of ionic species, which has been demonstrated to yield anion‐derived electrode–e...
Precision Photochemistry: Every Photon Counts
Abstract Photochemistry is undergoing a precision transformation. Through technological advancements, such as the advent of light emitting diodes and monochromat...
Confining Asymmetrically Coordinated Cobalt Single‐Atoms/Clusters on Holey MXene for Ultrafast Fenton‐Like Catalysis
Abstract Developing single‐atom catalysts (SACs) with asymmetric coordination configurations is essential for enhancing peroxymonosulfate (PMS) activation in Fen...
Metal‐Covalent Organic Frameworks: Design Strategy, Structure Feature, and Applications in Energy Storage
Abstract Metal‐covalent organic frameworks (MCOFs), which can integrate the properties of metal‐organic frameworks (MOFs) and covalent organic frameworks (COFs),...
An Atomically Precise Copper Cluster Nanoreactor for Efficient Catalysis in Chemical Fixation of Low‐Concentration CO <sub>2</sub>
Abstract Chemical fixation of CO 2 with propargylic amines/alcohols into high value‐added fine chemicals represents promi...
Multipoint Coordinative Capture of Olefinic Substrates Utilizing Metal‐Carbon Bonds by Macrocyclic Complex
Abstract Terpenoids and unsaturated fatty acids containing C═C double bonds are biologically and synthetically important compounds. The transformation of these s...
Thermodynamics of Water Displacement from Binding Sites and its Contributions to Supramolecular and Biomolecular Affinity
Abstract The role of water displacement in noncovalent binding has been debated in the fields of supramolecular chemistry and drug design. We use molecular dynam...
Nickel‐Catalyzed Sila‐Cycloaddition of Dichlorodisilanes: Selective Si─Cl Activation for Cyclic Disilanes and Enantioenriched Synthesis
Abstract Disilanyl architectures holds significant value across diverse fields, particularly in the development of advanced materials. However, their limited acc...
Stepwise Post‐Modification of Pyridine‐Imine COFs for Enhanced Hydrolytic Stability and Proton Conductivity
Abstract Emerging as a type of promising material for proton conduction, covalent organic frameworks (COFs) assembled from dynamic imine bonds face a challenge o...
Selective Electrochemical Production of Ethylene from Bicarbonate Solution
Abstract Carbon dioxide (CO 2 ) electroreduction directly from a reactive carbon solution (e.g., (bi)carbonate) provides...
Oriol Planas
Total Synthesis and Structural Revision of (−)‐Sodagnitin E
Abstract We report the total synthesis of malabaricane triterpene sodagnitin E, marking the first synthesis of any malabaricane natural product to date. The enantioselective synthesi...
A “Cocktail” Fluorescent Probe for Multi‐ROS Imaging Unveils Ferroptosis‐Driven Liver Fibrosis Development
Abstract Liver fibrosis is a pathological repair response to chronic liver injury and may progress to cirrhosis, liver failure, or hepatocellular carcinoma if un...
Microscale Tattooing of Hydrogels and Cells: Benzoxaborole‐Driven Microcontact Printing (µCP) on Glycosylated Surfaces
Abstract Microcontact printing (µCP) is a widely used technique for microscale surface patterning. In this study, we present a polymer‐supported µCP method for the patterning of (bio...
Engineering Neural Stem Cells with Micropatches for Improved Therapy of Traumatic Brain Injury
Abstract Transplantation of neural stem cells (NSCs) holds promise for repairing traumatic brain injury (TBI) but their therapeutic performance is hindered due to the low efficient d...