Angewandte Chemie International Edition
Articles in this Issue
Developing HaloTag and SNAP‐Tag Chemical Inducers of Dimerization to Probe Receptor Oligomerization and Downstream Signaling
Abstract Controlling protein–protein interactions is critical for dissecting signaling pathways, especially those initiated by ligand‐receptor interactions, which alter receptor olig...
Heterointerfacial Charge Modulation of p‐Type Covalent Organic Frameworks on Graphene Achieving High‐Performance Cl <sup>−</sup> Ion Storage with Ultralong Cycling Life
Abstract The charge and ion transport dynamics, storage capacity, and cycling performance of Faradaic Cl − ion storage el...
Vacancy‐Defect Single‐Atom Catalysts for Tandem CO <sub>2</sub> Electroreduction and Carbonylation Reactions from Flue Gas
Abstract Tandem CO 2 reduction with carbonylation reactions represents a promising approach to convert greenhouse gases i...
Bulk‐ and Surface‐Engineered Carbon Nitride with Promoted Electron Transfer for NADH Regeneration and Artificial Photosynthesis
Abstract Carbon nitride (CN), a well‐known photocatalyst, has been extensively utilized in light‐driven redox reactions, including NADH regeneration. However, its catalytic efficienc...
Concentration‐Adaptive Electrocatalytic Urea Synthesis From CO <sub>2</sub> and Nitrate via Porphyrin and Metalloporphyrin MOFs
Abstract Traditional urea synthesis via the Bosch–Meiser process suffers from high energy consumption and greenhouse gas emissions. Electrocatalytic urea product...
Accelerating Responsive RNA Release Through Structural Optimization of Disulfide‐Containing Acyl Groups
Abstract Chemical methods for modifying and manipulating RNA are crucial for advancing its biological studies and applications. While postsynthetic 2′‐OH acylation has enabled on‐dem...
S‐doped Ag–Sn Alloy Hollow Microbox for High‐Performance CO <sub>2</sub> Electroreduction to Formate
Abstract The dynamic catalyst's restructuring creates a new catalytic surface that is essential for boosting the efficiency of electrochemical carbon dioxide red...
Unlocking Dual Recycling in Photo‐Curable Polycyanurate Thermosets Derived from Bio‐Resources
Abstract Polycyanurate thermosets are extensively utilized in high‐performance applications due to their exceptional thermal and mechanical properties. However,...
Twelvefold Dearomative Esterification of (6,6)Carbon Nanobelt
Abstract Carbon nanobelts (CNBs), cyclic aromatic hydrocarbons with belt‐shaped topologies, have growing interest as structurally unique and optoelectronically promising nanocarbons....
Breaking the Activity‐Selectivity Trade‐off in Direct Levulinate Hydrodeoxygenation to Pentanoic Biofuels over La‐Modulated Ru‐Zeolite Catalysts
Abstract Disentangling the activity‐selectivity trade‐off in hydrodeoxygenation (HDO) of biomass‐derived oxygenates has been a great challenge in biomass valoriz...
Catalyst‐Engineered Proton Transfer Pathways for Selective Hydrogen Peroxide Electrosynthesis in Solid‐State Electrolytes
Abstract Polymer‐based solid electrolyte (SE) cells promise electrochemical synthesis of pure hydrogen peroxide (H 2 O...
Selective Nanopore Detection of Monoamine Oxidase A and B in a Single Sample
Abstract Monoamine oxidases A and B (MAO‐A and MAO‐B) are key enzymes involved in neurotransmitter metabolism and are critical biomarkers for neurodegenerative and psychiatric disord...
A Multivalent Targeting Strategy for Developing Reactive Oxygen Species‐Activated Tumor‐Seeking Probe to Guide Precise Surgical Resection
Abstract Optical molecular imaging with near‐infrared (NIR) dyes provides a promising strategy for the visual detection of tumor tissues. However, conventional m...
Scalable Hyperpolarized MRI Enabled by Ace‐SABRE of [1‐ <sup>13</sup> C]Pyruvate
Abstract Hyperpolarized (HP) MRI using [1– 13 C]pyruvate is emerging as a promising molecular imaging approach. Among hyp...
Cobalt‐Catalyzed Stereodivergent Semihydrogenation of Alkynes: Synthesis of <i>E</i> ‐ and <i>Z</i> ‐Alkenes
Abstract Transition metal‐catalyzed semihydrogenation of alkynes is one of the most efficient, sustainable, and environmental‐friendly strategies for accessing s...
A Macrocycle‐Based Supramolecular Strategy for Interchangeable Screwdriver‐Like on‐Demand Post‐Functionalization of Covalent Organic Framework
Abstract Constructing functionalized covalent organic frameworks (COFs) through post‐functionalization constitutes one of the most important approaches to applications, but is freque...
Hydrogen‐Bonding‐Assisted Assembly of Stable High‐Nuclearity Copper(I)‐Alkyne Nanoclusters for X‐Ray Scintillation
Abstract The construction of high‐nuclearity, atomically precise copper(I)‐alkyne nanoclusters remains a formidable challenge due to their high reactivity and st...
Nylon‐6 Precursor Electrosynthesis From Low‐Concentration NO via Carbon‐Enhanced NO Adsorption and Improved Mass Transfer
Abstract Cyclohexanone oxime electrosynthesis from low‐concentration NO is important but suffers from low Faraday efficiency and current density because of sever...
A 3.8 V Quaternary Ammonium‐Based Dual‐Ion Battery Enabled by a Conjugated Ladder Polymer
Abstract Rechargeable batteries based on nonmetal charge carriers like NH 4 + recently have attracted...
Fused‐Heterocycle‐Linked Covalent Organic Frameworks With Enhanced Chemical and Photochemical Stability for Photocatalysis
Abstract Covalent organic frameworks (COFs) have attracted significant interest for their potential in photocatalytic solar fuel generation. However, their intri...
High‐Pressure Synthesis of Crystalline Double‐Layer Carbon Nitride Networks Stabilized in Bi <sub>7</sub> C <sub>10</sub> N <sub>18</sub> (N <sub>3(1‐</sub> <i> <sub>x</sub> </i> <sub>)</sub> O <sub>3</sub> <i> <sub>x</sub> </i> )
Abstract Application of high‐pressure conditions in chemical synthesis has proven to access a wide range of novel nitrogen‐rich compounds and to overcome the sta...
Ru Single Atoms Anchored in Metal Borides Enable Hydrogen Spillover for Superior Electrochemical Ammonia Production
Abstract The electrochemical reduction of nitrate represents a promising and sustainable route for valuable ammonia generation. However, a vital challenge in the...
A Bioinspired Diazafluorenone Catalytic System for Aerobic Oxidative Deamination of Primary Amines
Abstract Copper amine oxidases (CAOs) catalyze aerobic oxidation of primary amines into carbonyl compounds, which is an important biological process as well as a useful transformatio...
Structural Differentiation of Homologous Anisodimensional Frameworks Driven by Site‐Selective Polymerization
Abstract Theoretically, distinguished from the dimensional isomers in reticular chemistry, structures with different dimensions can also be formed by site‐selective polymerization us...
Stable Acrylamide‐Linked Covalent Organic Frameworks via Mannich Polymerization for Efficient Gold Recovery from Complex E‐Waste Leachates
Abstract Achieving both high stability and selectivity remains a critical challenge in covalent organic frameworks (COFs) for efficient gold recovery. Herein, we...