Angewandte Chemie International Edition
Articles in this Issue
Unveiling the Power of Dark State Photocages: An Efficient Pathway to Triplet State Under Near‐Infrared Light Irradiation
Abstract The photocage platform provides a synergistic approach to photodynamic therapy (PDT) and chemotherapy. Before light activation, both pro‐photosensitizer...
Merging Photocatalysis with Chiral Lewis Acid Catalysis for Enantioselective Hydrosilylation/Hydrogermylation of Electron‐Deficient Alkenes
Abstract Organosilicon compounds demonstrate widespread applications in many fields. Transition‐metal‐catalyzed asymmetric hydrosilylation represents one of the most common and effec...
Dynamically Dual‐Center Coupled Synergistic Catalysis for Highly Efficient Oxygen Reduction
Abstract The oxygen reduction reaction (ORR) suffers from inherent kinetic limitations arising from the competitive adsorption behavior of *OOH intermediates and...
Regulate the Singlet–Triplet Energy Gap by Spatially Separating HOMO and LUMO for High Performance Organic Photovoltaic Acceptors
Abstract Reducing the single‐triplet energy gap (∆ E ST ) for organic photovoltaic (OPV) molecules ha...
Site‐Blocking Strategy Boosts H <sub>2</sub> S Tolerance in Platinum‐Based Hydrogen Oxidation Catalysts
Abstract Proton exchange membrane fuel cells (PEMFCs) show great potential for energy conversion, but their platinum‐based hydrogen oxidation reaction (HOR) cata...
NiH‐Catalyzed Enantio‐ and Regioselective Hydroarylation of Unactivated Alkenes Enabled by Outer‐Sphere Electron Transfer with Diaryliodonium Salts
Abstract Asymmetric hydroarylation of unactivated alkenes provides a direct route to enantiomerically enriched C─C bonds in aryl‐containing compounds, a key transformation in pharmac...
EDTA‐Mg Nano‐Chelators Amplify Ferroptosis by Artificially Simulating the Epithelial‐Mesenchymal Transition Process and Endogenous Iron Deprivation
Abstract Epithelial‐mesenchymal transition (EMT) is a key step in initiating tumor metastasis. Commonly, researchers focus on inhibiting EMT to prevent tumor met...
Entire Near‐Infrared‐I Electrochemiluminescence Enhancement of Gold Nanoclusters
Abstract Herein, entire near‐infrared‐I (NIR‐I) electrochemiluminescence (ECL) enhancement of gold nanoclusters (Au NCs) is achieved by continuously regulating the plasmon resonance...
Outside Back Cover: Light‐Driven Ratchet Mechanism Accelerates Regioselective Metal‐Cation Exchange in a Heterobimetallic Helicate (Angew. Chem. Int. Ed. 35/2025)
Tuning Encodable Tetrazine Chemistry for Site‐Specific Protein Bioorthogonal Ligations
Abstract Using genetic code expansion (GCE) to encode bioorthogonal chemistry has emerged as a promising method for protein labeling, both in vitro and within cells. Here, we demonst...
Suppressing Halide Segregation of Wide Bandgap Perovskite by Interface Molecular Coordination for High‐Performance All‐Perovskite Tandem Solar Cells
Abstract Hole transporting layers made by self‐assembled molecules (SAMs) are emerging as promising hole transporting materials (HTMs) for perovskite‐based tande...
Asymmetric, Corner‐Sharing CuO <sub>5</sub> and CuO <sub>6</sub> Motifs in Cu‐Based Metallic Perovskite Oxides Boosting Asymmetric C─C Coupling for CO <sub>2</sub> Electroreduction to C <sub>2+</sub>
Abstract Cu‐based perovskite oxides feature significant potential for CO 2 electroreduction (CO 2...
Symmetry Breaking Enabled Stable Oxygen Redox in Li‐Rich Cathodes via π‐Type Interaction
Abstract Effectively stabilizing oxygen redox is the most challenging task for the practical applications of high‐energy‐density Li‐rich cathode materials. Howev...
Remote and Spatiotemporal Modulation of Supramolecular Self‐Assembly of Croconaine Dyes via NIR Laser Irradiation
Abstract Supramolecular polymerization holds great promise for the fabrication of well‐defined nanostructures. However, achieving precise spatiotemporal control over the dynamic asse...
A Bifunctional Organic Photocatalyst for Efficient Single‐Electron and Energy Transfer Activation
Abstract Bifunctional photocatalysts capable of mediating both single‐electron transfer (SET) and energy transfer (EnT) processes are rare and typically metal ba...
Selective and Energy Efficient Electrocatalytic CO <sub>2</sub> ‐to‐Ethanol Conversion through Anion Modulation
Abstract Ethanol, with its high market value and stable global demand, stands out as an attractive product of electrocatalytic CO 2...
Acetone Derivatives for Nickel‐Catalyzed Methylation, Trideuteromethylation, and <sup>13</sup> C‐Methylation of (Hetero)Aryl Chlorides
Abstract The development of low‐cost, readily available, and broadly applicable reagents for the methylation, trideuteromethylation, and 13...
Long‐Range Electronically Polarized Fe‐N <sub>5</sub> Catalysts Redirect Polymerization‐Driven Phenolic Pollutant Removal Toward Sustainable Carbon Sequestration
Abstract A sustainable strategy for simultaneous pollutant removal and carbon sequestration is offered by the peroxymonosulfate (PMS)‐mediated electron transfer...
NonCovalent Aggregation‐Driven D‐Band Engineering in Nickel Cocatalysts for Efficient CO <sub>2</sub> Photoreduction
Abstract Efficient CO 2 activation remains a pivotal challenge in photocatalytic CO 2...
Topochemical Polymerization of Retro‐Isomeric Peptides for Tuning the Polymer Structure and Properties
Abstract Peptidomimetic polymers containing hydrophobic amino acids and nonpeptidic linkages are interesting for various applications, particularly hydrophobic c...
Revealing the Correlation of Loading‐to‐Performance of Single Atom Catalysts
Abstract The correlation between metal loading and overall catalytic performance remains elusive for single‐atom electrocatalysts (SACs), which hinders the orien...
Framework Nucleic Acid‐Mediated DNAzyme Chaperoning for Sensitive Trace Metal Ion Mapping on Live Neuronal Cell Membranes
Abstract The transient release of metal ions at neuronal cell membranes holds significant implications in neurophysiology and pathology. Consequently, there is a...
Sulfur Mediated Interfacial Proton‐Directed Transfer Boosts Electrocatalytic Nitric Oxide Reduction to Ammonia over Dual‐Site Catalysts
Abstract Electrocatalytic nitric oxide reduction reaction (NORR) for ammonia (NH 3 ) synthesis represents a sustainable s...
Local Electric Field Microenvironment‐Induced Dynamic Spatial Confinement to Stabilize I <sup>+</sup> Toward High‐Mass‐Loading and Stable Zinc–Iodine Batteries
Abstract Four‐electron iodine conversion chemistry (I −/ I 2 /I...