Angewandte Chemie International Edition
Articles in this Issue
The Chemistry and Biology of the Tetrodotoxin Natural Product Family
Abstract Tetrodotoxin is a neurotoxic marine alkaloid, first isolated in 1909 from pufferfish and named after the biological order tetraodontiformes. Since its structural elucidation...
Enhanced Active Hydrogen Absorption and Stabilized Cu(I) Species Over Cu‐O‐Ce Bridges Boosting Electrocatalytic CO <sub>2</sub> Reduction to Ethylene
Abstract Rational design of water activation center to promote active hydrogen (*H) generation and stabilize Cu(I) species are significant for the formation of m...
Reduction of CO <sub>2</sub> Accompanying ATP Synthesis in Polydopamine Microreactors Covered by Lipid Bilayers with ATPase
Abstract Global energy and environmental crises have stimulated increased efforts toward converting CO 2 into valuable ch...
Porous Organic Cages as Building Blocks for Framework Materials
Abstract Confined nanospaces play a fundamental role in nature, inspiring synthetic analogues that emulate biological precision and efficiency. Among these, porous crystalline materi...
Single‐Molecule Electrochemiluminescence Imaging of Plasmonic Hot Spot Reactivity
Abstract Localized surface plasmon resonance (LSPR), an important optical property of noble metal nanomaterials, is extensively applied in electrochemistry. Howe...
Gram‐Scale Access to (3,11)‐Cyclotaxanes—Synthesis of 1‐Hydroxytaxuspine C
Abstract Herein, we present the semisynthesis of complex taxane diterpenoid 1‐hydroxytaxuspine C. Starting from cheap and abundant 10‐deacetylbaccatin III, a scalable and robust rout...
Low Molecular Weight Multistate Photoswitches Based on Simple Norbornadiene‐Triazine Scaffolds
Abstract We have synthesized and characterized a series of simple norbornadiene(NBD)‐triazine architectures, including multistate photoswitches with unprecedente...
Bicyclic Selenenyl Sulfides with Tuned Bioreductive Step Rates Reveal Constraints for Probes Targeting Thioredoxin Reductase
Abstract The reductive activation of dichalcogenide probes by thiol‐type oxidoreductases proceeds through a cascade of consecutive, partly reversible steps. Ster...
Intermolecular Sp <sup>3</sup> C─H Metalation of Non‐Nucleophilic Brønsted Bases Using Simple Lewis Acids
Abstract 2,6‐Di‐ tert ‐butyl substituted pyridines ( t...
Side‐On Coordination in Molecular Alkaline Earth Metal Hypofluorites FM(η <sup>2</sup> ‐OF) (M = Mg, Ca, Sr, and Ba)
Abstract Side‐on coordinated molecular hypofluorites FM(η 2 ‐OF) (M = Mg, Ca, Sr, and Ba) were prepared by co‐deposition...
Larissa K. S. von Krbek
Light‐Driven Ratchet Mechanism Accelerates Regioselective Metal‐Cation Exchange in a Heterobimetallic Helicate
Abstract Molecular machines rely on their capacity to exploit non‐equilibrium processes to perform work. However, the development of these non‐equilibrium proces...
Solid‐State NMR Reveals Reorganization of the <i>Aspergillus fumigatus</i> Cell Wall Due to a Host‐Defence Peptide
Abstract The limited availability of antifungal drug treatments and the rising issue of drug resistance highlight the urgent need for new antifungal drugs to com...
Superprotonic Conduction Over Wide Humidity Range Driven by Enhanced Proton Dissociation
Abstract Proton‐conducting materials play a key role in various fields, and their proton conduction is profoundly restricted by the proton dissociation process....
Deconstructive Radical–Radical Coupling for Programmable Remote Acylation
Abstract Dicarbonyl compounds are structural motifs that have been extensively utilized in synthetic chemistry, and their downstream transformations have proven valuable in synthesiz...
Glycosylation‐Dependent Stability of Human Pentraxin‐2 Revealed by Surface‐Induced Dissociation and Ion Mobility Mass Spectrometry
Abstract Pentraxin‐2 (PTX‐2), also known as Serum Amyloid P component, functions as an immunoregulatory glycoprotein and plays a crucial role in fibrotic diseases such as idiopathic...
Near‐Infrared Light Catalysis of Carbon Dioxide Reduction by Conjugated Porous Aromatic Frameworks
Abstract Current CO 2 photocatalytic systems mainly work in ultraviolet (UV) and visible (Vis) light regions, and the ina...
Regio‐, Diastereo‐, and Enantioselective Hydrosilylation of Alkyl <i>gem</i> ‐Difluoroalkenes to Construct Carbon and Silicon Stereogenic Centers
Abstract The asymmetric hydrofunctionalization of aliphatic alkenes without auxiliary or stabilizing groups presents a significant challenge in modern organic sy...
Efficient Red Light–Driven Singlet Oxygen Photocatalysis with an Osmium‐Based Coulombic Dyad
Abstract Photoactive osmium complexes are widely used sensitizers for the generation of singlet oxygen because they can be excited directly into their triplet st...
Magneto‐Luminescence Thermometry with Magnetic Circularly Polarized Luminescence
Abstract Lanthanide(III) materials display remarkable optical properties, making them valuable for advancing remote luminescent sensors. The narrow emission band...
Homologous Ladder Cyclohexasilanes
Abstract We report the synthesis of five new examples of ladder cyclohexasilanes, possessing up to three consecutive fused rings and differing in relative ring f...
Dual Cofactor Co‐Decorated Covalent Organic Framework as an Electron Transfer Regulator for Biomimetic Dioxygen Activation
Abstract Mimicking the synergy of multiple active sites of oxygenase to achieve selective O 2 activation for various oxid...
Exploring Excited State Proton Transfer in Thin Films Under Vibrational Strong Coupling
Abstract Molecular structure, solvent/matrix, the surrounding environment, and molecular vibrations can influence the excited‐state proton transfer (ESPT) proces...