Angewandte Chemie International Edition
Articles in this Issue
Decoding the Chemical Language of Ribosomally Synthesized and Post‐Translationally Modified Peptides from the Untapped Archaea Domain
Abstract Chemical communication is crucial in ecosystems with complex microbial communities. However, the difficulties inherent to the cultivation of archaea have led to a limited un...
Ligand‐Controlled Regiodivergent Carbosilylation of 1,3‐Dienes via Nickel‐Catalyzed Three‐Component Coupling Reactions
Abstract The regiodivergent carbosilylation of 1,3‐dienes presents a formidable challenge due to inherently complex selectivity control over multiple potential reaction pathways. Her...
Electrostatic Potential Matching in an Anion‐Pillared Framework for Benchmark Hexafluoroethane Purification from Ternary Mixture
Abstract One‐step purification of CF 3 CF 3 from ternary CF 3...
A Method for Constructing Nucleosome Arrays with Spatially Defined Histone PTMs and DNA Damage
Abstract DNA damage repair mechanisms, such as base excision repair (BER), safeguard cells against genotoxic agents that cause genetic instability and diseases, including cancer. In...
Bis(pinacolato)Diboron‐Enabled Nickel‐Catalyzed Regio‐ and Enantioselective Reductive [3 + 2] Annulation of β‐Bromoenones with Alkynes
Abstract Chiral five‐membered cyclic tertiary alcohols are important structural motifs in functional materials, pharmaceuticals, and bioactive molecules. Hence,...
Rhodium‐Catalyzed Atroposelective Synthesis of Axially Chiral 1‐Aryl Isoquinolines via De Novo Isoquinoline Formation
Abstract Axially chiral heterobiaryl moieties serve as core skeletons for bioactive molecules, chiral ligands, and organocatalysts. Enantioselective de novo formation of the heteroar...
Photovoltaic Absorber “Glues” for Efficient Bifacial Selenium Photovoltaics
Abstract Bifacial solar cells hold great potential for achieving higher power output than conventional monofacial devices by harvesting solar irradiance from both their front and rea...
Vacancy and Dopant Co‐Constructed Active Microregion in Ru–MoO <sub>3−</sub> <i> <sub>x</sub> </i> /Mo <sub>2</sub> AlB <sub>2</sub> for Enhanced Acidic Hydrogen Evolution
Abstract Accurate identification of catalytic active regions is crucial for the rational design and construction of hydrogen evolution catalysts as well as the t...
Redox‐Controlled, Sequential Self‐Sorting of Supramolecular Assemblies in Model Protocells
Abstract Self‐sorting of cellular components is essential for maintaining order and function in living systems, enabling complex processes to operate seamlessly. Emulating such self‐...
<i>Cyclo</i> ‐P <sub>5</sub> <sup>−</sup> Revisited: The Surprisingly Stable Uncoordinated Pentaphospholide Anion
Abstract The addition of [2.2.2]cryptand to alkali metal heptaphosphides M 3 P 7...
An Immediate Bacterial‐Responsive Supramolecular Thio‐Naphthalene Diimide: A Real‐Time NIR‐II Photothermal Anti‐Bacterial
Abstract A new kind of supramolecular thio‐naphthalene diimide (SNDI) which can be immediately reduced as supramolecular radical anion by bacteria is reported. The introduction of th...
Redox‐Mediated Lithium Recovery From Spent LiFePO <sub>4</sub> Stabilizes Ferricyanide Catholyte for Durable Zinc‐Ferricyanide Flow Batteries
Abstract The scarcity of lithium resources and the increasing volume of spent lithium‐ion batteries (LIBs) exacerbate the imbalance between lithium supply and de...
Remote Spin‐Center Shift Enables Activation of Distal Benzylic C─O and C─N Bonds
Abstract A spin‐center shift (SCS) is a radical process that commonly involves a 1,2‐radical shift along with the elimination of an adjacent leaving group by a t...
Late‐Stage Cross‐Electrophile Coupling of Arylthianthrenium Salts with (Hetero)aryl (Pseudo)halides via Palladium Catalysis
Abstract Herein, we present a cross‐coupling reaction of arylthianthrenium salts at a late stage with diverse (hetero)aryl (pseudo)halides under reductive conditions, in which a pall...
Discovery and Biosynthesis of Celluxanthenes, Antibacterial Arylpolyene Alkaloids From Diverse Cellulose‐Degrading Anaerobic Bacteria
Abstract Cellulose degradation by anaerobic bacteria plays an eminent role in the global carbon cycle and is a critical step in biofuel production. The anaerobic...
Bioinspired Cationic Antimicrobial Polymers
Abstract Antibiotics are an essential tool of modern medicine, which is critically endangered by the spread of antimicrobial resistance (AMR). Without effective antibiotics, a number...
Direct Conversion of Aromatic Lactones into Bioisosteres by Carbonyl‐to‐Boranol Exchange
Abstract Bioisosteric replacement is an important strategy in drug discovery and is commonly practiced in medicinal chemistry; however, the incorporation of bioisosteres typically re...
Superfast Protein Desulfurization Triggered by Low‐Energy Visible Light
Abstract The combination of transthioesterification‐based ligation of thiol‐derived amino acids and the post‐ligation desulfurization has greatly expanded the scope of modern chemica...
Synthesis and Characterization of Circumtetracene: Unraveling Structure‐Property Relationships of Circumacenes
Abstract Circumacenes have garnered significant interest in both fundamental science and nanoelectronics due to their unique electronic structures. However, their synthesis and inves...
Effect of Alternating Polarity in Electrochemical Olefin Hydrocarboxylation
Abstract The electrochemical generation of radical anions from feedstock olefins offers a selective and efficient route for synthesizing commodity chemicals and pharmaceutical precur...
DNA‐Based Signal Circuit for Self‐Regulated Bidirectional Communication in Protocell‐Living Cell Communities
Abstract Developing synthetic biology tools to control cell‐to‐cell signaling can provide new capabilities to engineer cell‐cell communication and program desired cellular behaviors....
Cobalt‐Metalated 1D Perylene Diimide Carbon‐Organic Framework for Enhanced Photocatalytic <i>α</i> ‐C(sp <sup>3</sup> )─H Activation and CO <sub>2</sub> Reduction
Abstract The photocatalytic activation of inert C(sp 3 )─H bonds in saturated aza...
Highly Selective Oxygen Electroreduction to Hydrogen Peroxide on Sulfur‐Doped Mesoporous Carbon
Abstract As a paradigm‐shifting material platform in energy catalysis, precisely engineered ordered mesoporous carbon spheres emerge as supreme metal‐free electr...
Outside Back Cover: Data–Knowledge‐Dual‐Driven Electrolyte Design for Fast‐Charging Lithium Ion Batteries (Angew. Chem. Int. Ed. 24/2025)
Functionalized Cyclic Poly(α‐Hydroxy Acids) via Controlled Ring‐Opening Polymerization of O‐Carboxyanhydrides
Abstract Linear poly(α‐hydroxy acids) are important degradable polymers, and they can be efficiently prepared by ring‐opening polymerization of O‐carboxyanhydrides with pendant funct...