Angewandte Chemie International Edition
Articles in this Issue
Complementary Hydrogen─Bonded Functionalized Mixed Conducting Terpolymers for High‐Performance n‐type Organic Electrochemical Transistors and Healable Inverters
Abstract High‐performing n‐type organic electrochemical transistors (OECTs), crucial for integrated circuits in wearable bioelectronics, demand organic mixed ion...
Protein Secondary Structure Patterns in Short‐Range Cross‐Link Atlas
Abstract Cross‐linking mass spectrometry (XL‐MS) has become a powerful tool in structural biology for investigating protein structure, dynamics, and interactomics. However, short‐ran...
Microhydration Dynamics in Molecular Photoswitches: Equilibrium State Reconfiguration in Imine‐Based Architectures
Abstract The functional performance of a molecular photoswitch relies strongly on its ability to undergo structural changes in solution. In this context, microsolvation studies in th...
Access to Diverse Activatable Heptamethine Cyanine Probes with Low Intrinsic Fluorescence via 5‐ <i>exo‐trig</i> Cyclization Strategy for High‐Contrast Bioimaging In Vivo
Abstract The conversion of conventional “always‐on” cyanine dyes into activatable NIR probes with low inherent fluorescence remains challenging, resulting in poo...
Anomalous pH‐Dependence of Ru for Hydrogen Electrochemistry
Abstract The essence of the classic pH‐dependent catalytic behavior of Pt toward hydrogen electrochemistry has been debated for decades. In stark contrast, Ru represents a unique exc...
Phototransposition of Indazoles to Benzimidazoles: Tautomer‐Dependent Reactivity, Wavelength Dependence, and Continuous Flow Studies
Abstract Herein, we report a detailed investigation of the photomediated transformation of indazoles to benzimidazoles through a nitrogen–carbon transposition. T...
Light‐Responsive DNA Droplets for Controlling Enzyme Cascade Pathways by Dynamic Phase Separation
Abstract Precise control of enzymatic cascade pathways is essential for deepening our understanding of metabolic processes and designing synthetic biochemical systems. In this study,...
Large N‐Doped Zigzag Hydrocarbon Belts from Calixarenes: Synthesis, Structure, and Properties
Abstract Zigzag hydrocarbon belts and heteroatom‐doped analogs have captivated chemists because of their unique structures, tantalizing properties, and potential...
Incorporation of Dye‐Derived Carbon Dots Into Carbon Nitride Nanosheets for Enhanced Photoinduced Atom Transfer Radical Polymerization
Abstract Carbon dots have made significant advancements in photoinduced atom transfer radical polymerization (photo‐ATRP), achieving ultrafast reaction rates and...
Machine Learning‐Augmented Molecular Dynamics Simulations (MD) Reveal Insights Into the Disconnect Between Affinity and Activation of ZTP Riboswitch Ligands
Abstract The challenge of targeting RNA with small molecules necessitates a better understanding of RNA–ligand interaction mechanisms. However, the dynamic nature of nucleic acids, t...
Methanol‐Facilitated Cascaded Polyolefin Upcycling Enabling the Efficient Generation of High‐Value C <sub>9+</sub> Alkylaromatics
Abstract Existing polyolefin chemical recycling and upcycling strategies predominantly yield fuels, waxes, and olefins, which are characterized by relatively low...
Photoswitchable Antimicrobial Metallohelices
Abstract Chiral subcomponent self‐assembly is used to access optically pure, metallo‐helical species based on Zn and Fe(II) and incorporating three transazobenze...
A Cu‐Pb Hybrid Layer Architecture as a New Structural Prototype for High‐Efficiency 2D Double Perovskite Broadband Emitters
Abstract Two‐dimensional (2D) organic lead halide perovskites have emerged as promising next‐generation luminescent materials due to their high chemical versatil...
A Shelf‐Stable Reagent for Photocatalytic Radical Pentafluorosulfanylation of Styrene Derivatives
Abstract We have developed the first family of air‐ and moisture‐stable pentafluorosulfanylation (SF₅) reagents. Although the SF₅ group is a bioisostere of the trifluoromethyl group...
Suppressing the Interface Photodegradation towards Efficient and Stable All Perovskite Tandem Solar Cells
Abstract All perovskite tandem solar cells (PTSCs) were expected to overcome the Shockley‐Queisser limit of single‐junction perovskite solar cells (PSCs). Nevert...
Operando Magnetic Resonance Imaging for Visualizing Electrochemical Triple‐Phase Boundary
Abstract The triple‐phase boundary (TPB) is a complex interface where gas, liquid, and solid phases converge, crucially regulating the efficiency and performance...
Ether‐Oxygen Groups Modified Carboxylic Ester Enabling High‐Voltage Lithium Metal Batteries
Abstract Lithium metal batteries (LMBs) operating at high cut‐off voltages can achieve an energy density exceeding 500 Wh kg −1...
Sn Catalysts with Build‐in [NCN] <sup>2−</sup> as Proton Relay for Industrial‐Grade CO <sub>2</sub> Reduction at Low Overpotential
Abstract Electrochemical CO 2 reduction (ECO 2 R) involves multiproton electron t...
Efficient Bicarbonate Electrolysis to Formate Enabled via Ionomer Surface Modification in Cation Exchange Membrane Electrolyzers
Abstract Electrochemical CO 2 reduction (CO 2 RR) is a promising method for conve...
Reversible Trace‐Water‐Buffering Frameworks for Efficient Humid Methane Purification
Abstract Trace water is usually fatal to gas separation process because the adsorption sites of adsorbents can be readily devitalized under humid conditions. Her...
Universal Metal‐Exchange Strategy for Room Temperature Synthesis of Single‐Atom Nanozymes
Abstract The high‐temperature limitations of single‐atom catalysts (SACs) synthesis, primarily thermal aggregation and low metal loadings, are overcome by a novel room‐temperature me...
Guest Polarizability Directed Molecular “Freezing” Within Non‐metal Porous Salt Frameworks
Abstract Isoreticular non‐metal salt frameworks with permanent porosity have emerged recently as a fantastic platform for molecular separation, but the underlyin...
<i>ortho</i> ‐C─H Alkylation of Aryl Chlorides by a Catellani Strategy
Abstract Herein we report a general and practical palladium/norbornene catalysis system that effectively promotes difunctionalization of less reactive aryl chlor...
Synthesis of Chroman Derivatives by Group Transposition and Atom Swapping in 1‐Tetralones: Single‐Atom Editing Enabled by Oxidative Ring Contraction of Benzoxepine Silyl Ketene Acetals
Abstract Single‐atom editing of complex molecules is steadily filling the chemical toolbox with site‐selective modification reactions. Herein, a stepwise scheme for carbon‐to‐oxygen...
Unveiling Nonadiabatic Pathways in Small Molecule Activation: Dinuclear Uranium‐Mediated H <sub>2</sub> and N <sub>2</sub> Bond Cleavage
Abstract Nonadiabatic effects have been extensively studied in photoexcited processes, but their role in thermal process so far has neither been thoroughly studi...