Angewandte Chemie International Edition
Articles in this Issue
The ConPET Mechanism Remains Veiled: Reply to “Unlocking the ConPeT Mechanism”
Abstract In this journal, a Correspondence by Ventura, Cozzi, and Ceroni reported time‐resolved absorption spectroscopy studies in the electron transfer process...
Alkali Metal Cations Impact the Selectivity of Radical‐Mediated Electrochemical C─H Chlorination
Abstract Electrochemistry offers a promising route toward facilitating organic transformation reactions in a sustainable manner. However, there are often a multi...
Design of Tough 3D Printable Elastomers with Human‐in‐the‐Loop Reinforcement Learning
Abstract The development of high‐performance elastomers for additive manufacturing requires overcoming complex property trade‐offs that challenge conventional material discovery pipe...
Conditional Stabilization of the Hypoxia‐Inducible Factor HIF1α— Photoswitchable Stapled Peptides Prevent Elongin BC–Mediated Degradation
Abstract Oxygen levels and its distribution are tightly regulated due to their critical impact on health. Hypoxia‐inducible factors (HIFs) are traditionally reco...
Establishing 3 <i>d</i> –4 <i>d</i> Orbital Hybridization for Efficient Photothermal Catalytic CO <sub>2</sub> Hydrogenation
Abstract Photothermal catalytic CO 2 conversion offers a promising way to address the energy and environmental issues; ho...
C(sp <sup>2</sup> )─H Bond Activation with a Heterometallic Nickel–Aluminium Complex
Abstract Herein we present a ligand‐catalyzed bond‐breaking and making process that occurs with a Ni–Al heterometallic complex. While combinations of Ni pre‐cata...
Synergy of Oxygen Vacancies and Ni Single Atoms Toward Efficient Urea Photosynthesis from CO <sub>2</sub> and N <sub>2</sub>
Abstract The direct photochemical synthesis of urea under mild conditions presents considerable promise. Nevertheless, the photocatalytic urea synthesis is sever...
The Diels–Alder Reaction as a Mechanistic Probe for Vibrational Strong Coupling
Abstract Vibrational Strong Coupling (VSC) has recently been reported to alter reaction kinetics. Hypotheses on how it does this have been proposed, but open questions remain regardi...
Synergistic Self‐Assembled Monolayers Reinforce Buried Interface Anchoring for High‐Efficiency Tandem Perovskite Solar Cells
Abstract Carbazole‐based self‐assembled monolayers (SAMs) have been commonly used as a single‐component hole transport layer (HTL) in inverted perovskite solar c...
Metalloenzyme‐Catalyzed Asymmetric Transfer Hydrogenation for the Synthesis of Chiral Amines
Abstract Chiral amines are prevalent in natural products, pharmaceuticals, and organic catalysts. Their increasing demand has driven the advancement of synthetic methods. In this stu...
A C‐to‐B Atom Swap on Coumarins and Dibenzolactones
Abstract We report a carbon‐to‐boron “C‐to‐B” atom swap reaction to transform readily available coumarins into their isosteric benzoxaborins via a net replacement of the C═O group wi...
The Overlooked Dual Phosphorescence of Lappert's Diamino Stannylene Sn[N(SiMe <sub>3</sub> ) <sub>2</sub> ] <sub>2</sub>
Abstract The first stable heavy carbene homologues, the heavy tetrylenes, were reported in 1973 by Lappert and coworkers. These tetrylenes were extensively inves...
Revealing Parallel Inter‐ and Intra‐Ligand Charge Transfer Dynamics in [Ru(L) <sub>2</sub> (dppz)] <sup>2+</sup> Molecular Lightswitch with N K‐Edge X‐Ray Absorption Spectroscopy
Abstract In photoactive metal complexes the localization of photoexcited charges dictates the site of chemical reactivity, but few studies measure the charge red...
Synergistic Covalently and Mechanically Interlocked Polymer
Abstract Integrating different polymer types into a unified system in a thoughtful manner leverages their complementary advantages, providing a promising strateg...
Outside Front Cover: Conditional Stabilization of the Hypoxia‐Inducible Factor HIF1α: Photoswitchable Stapled Peptides Prevent Elongin BC–Mediated Degradation (Angew. Chem. Int. Ed. 36/2025)
Conduction Band Convergence and Modular Nanostructures: Driving High Thermoelectric Performance in <i>n</i> ‐Type PbSe
Abstract n ‐type lead chalcogenides showing high thermoelectric performance are rare due to the larger energy offset between the two lowest e...
Photoresponsive Slide‐Ring Gels Enable Modulation of Sliding Dynamics
Abstract Cyclodextrin‐based slide‐ring gels (SRGs) have emerged as a promising class of materials owing to their unique topology. Upon mechanical loading, the sl...
Synergistic Modulation of Intermediate Adsorption and Active Hydrogen Supply Enable Pulsed Nitrate‐to‐Hydroxylamine Electroreduction with Nearly 100% Faradaic Efficiency
Abstract Electrochemical hydroxylamine (NH 2 OH) synthesis from NO x under ambien...
Inside Front Cover: Is a Malleable Active Site Loop the Key to High Substrate Promiscuity? Hybrid, Biocatalytic Route to Structurally Diverse Taxoid Side Chains with Remarkable Dual Stereocontrol (Angew. Chem. Int. Ed. 36/2025)
Outside Back Cover: Metal‐Responsive Up‐Regulation of Bifunctional Disulfides for Suppressing Protein Misfolding and Promoting Oxidative Folding (Angew. Chem. Int. Ed. 36/2025)
High‐Efficiency Hydrogen Oxidation for Hydroxide Exchange Membrane Fuel Cells Catalyzed by Fivefold‐Twinned Nickel Nanoparticles
Abstract The independent regulation of multiple intermediates is critically important for optimizing the electronic structure of nickel (Ni), thereby improving i...
Selective Sieving Effect of Multi‐Atomic Bismuth Interfaces for Efficient Formate Electrosynthesis and Evolution at Industrial Current Density
Abstract Constructing multi‐atomic interfaces architectures is promising for electrocatalytic CO 2 conversion, yet their...
Dual‐Sided Multidentate Coordination Strategy Enables Record Birefringence in UV‐Transparent Antimony‐Based Hybrid Crystals
Abstract Achieving ultrahigh birefringence in UV‐transparent materials remains fundamentally constrained by the trade‐off between strong optical anisotropy and w...
Mitochondria‐Targeting Abasic Site‐Reactive Probe (mTAP) Enables the Manipulation of Mitochondrial DNA Levels
Abstract Mitochondrial DNA (mtDNA) encodes essential genes for mitochondrial and cellular functions and acts as a cell signaling molecule in innate immune and inflammatory responses....
A Guest Cation Screening Principle for Enabling Customized Cathode/Electrolyte Interface Chemistry and Self‐Enhanced Aqueous Zinc‐Ion Batteries
Abstract Intrinsic structural instability and sluggish reaction kinetics at the electrode/electrolyte interface are two critical concerns that block the applicat...