Angewandte Chemie International Edition
Articles in this Issue
Retro‐Diels–Alder‐Triggered Supramolecular Polymerization of Tetrabenzoporphyrin into Pyramidal Aggregates
AbstractSupramolecular polymerization of π‐extended compounds with hydrogen‐bonding sites remains challenging, especially at high concentrations, due to their limited solubility in nonpolar solvents....
A Highly Transparent Thermoplastic Synthesized from Ethylene that Melts Above 200 °C
AbstractPolyolefin‐based thermoplastics are the most widely used polymers and produced in megaton scale. Their applicability depends strongly on the melting point, and a high‐melting ethylene‐based pl...
Chiral Single Molecule with Biphenyl Component Exhibiting Both TADF and RTP Emissions Enables Highly Efficient CP‐OLEDs
AbstractChiral single molecules that exhibit both thermally activated delayed fluorescence (TADF) and room temperature phosphorescence (RTP) pose significant challenges, primarily due to their competi...
Continuous Flow Electrochemistry Unlocks Broadly Applicable Arene C─H Amination
AbstractThe direct C─H amination of arenes is a powerful strategy for synthesizing arylamines, yet existing methods often suffer from limited substrate scope, poor selectivity, or scalability issues,...
A Streamlined Approach to Indoles, Pyrroles, and Benzimidazoles via Redox‐Neutral Aromatization and CO Reduction Mediated by Cs<sub>2</sub>CO<sub>3</sub>
AbstractThe synthesis of nitrogen heteroarenes has a rich history, including many illustrious name reactions. These reactions often involve complex oxidative processes or the need for transition metal...
Molecular Scale Interfacial Water Management Switching Reaction Pathway of Carbon Dioxide Electroreduction
AbstractThe electrochemical carbon dioxide reduction reaction (eCO2RR) involves numerous intermediates and simultaneous interactions between these intermediates and water (H2O) molecules. Although ext...
De Novo Designed β‐Hairpin Peptides Mimicking the Copper‐Binding Histidine Brace Motif of Lytic Polysaccharide Monooxygenases
AbstractLytic polysaccharide monooxygenases (LPMOs) are Cu‐containing enzymes that play a crucial role in lignocellulosic biomass degradation for use in biofuel production. These enzymes carry out the...
Exploring Spin‐Electric Coupling in an Electrically‐Controlled Rare‐Earth Molecular Qubit
AbstractMagnetoelectric materials have attracted considerable interests due to their unique capability to facilitate reciprocal control between the charges and spins in matter. Based on electron param...
Helical Poly(isocyanide anthraquinones)‐Based Cathodes for Long‐Cycling Lithium Metal Batteries
AbstractThanks to the unique rigid conformation and designable side‐chain structure, helical polymers are starting to be more widely considered as ideal electrode materials in secondary batteries. In...
The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations
Abstract Photoenzymatic catalysis facilitates stereoselective new‐to‐nature chemistry under mild conditions. In addition to the rational design of artificial pho...
Hofmeister “Salting‐In” Assisted Slurry Homogenization for Ultra‐Thin Sulfide Solid‐State Electrolytes
AbstractSulfide‐based all‐solid‐state batteries (ASSBs) demand ultra‐thin electrolytes to achieve low impedance and high energy density, yet scalable fabrication remains bottlenecked by the incompatib...
Ligand Coordination Equilibria–Drived Homogeneous Electrodeposition Enables Coatings with Superior Corrosion Resistance and Mechanical Strength
AbstractElectroplating technology is crucial for interfacial engineering due to its flexible controllability and excellent protective performance. However, electroplated coatings often exhibit uneven...
From Flue Gas to Syngas: Composite Electrode Based on Ionic Liquid and Microporous Polymer for MEA‐Based CO<sub>2</sub> Electrolysis
AbstractThe electrochemical CO2 reduction reaction (ECO2R) offers a promising pathway to convert CO2 into value‐added products. While catalyst advances remain crucial, gas‐diffusion electrodes (GDEs)...
Harnessing the Dynamic Nature of a Zirconium‐Oxo Nanocluster for Reversible Protein Capture and Proteolysis
AbstractSelective proteolysis remains a significant challenge with relevance to industrial and pharmaceutical applications, motivating development of chemical strategies emulating the specificity of n...
Anchoring and Competition: Weakly Solvated Structure of Glymes Enhances Stability in Lithium Metal Batteries Operating under Extreme Conditions
AbstractLithium metal batteries (LMBs) face challenges from unstable and fragile solid electrolyte interphases (SEIs). In this work, we successfully develop a novel electrolyte by effectively modulati...
Improving Charge Extraction and Operational Stability in Inverted Perovskite Solar Cells with Conjugated Block Copolymers
AbstractA defect‐passivated, electronically benign interface is essential for high‐performance, stable perovskite solar cells (PSCs). Most conventional surface passivation strategies frequently introd...
Outside Front Cover: The Natural Redox Cofactor Pyrroloquinoline Quinone (PQQ) Enables Photocatalytic Radical Cyclizations (Angew. Chem. Int. Ed. 40/2025)
Light‐Induced Radical C(sp<sup>2</sup>)−H Trifluorovinylation of (Hetero)arenes with a Trifluorovinyl Iodine(III) Reagent (TrFVI)
AbstractTrifluorovinyl group is an emerging and valuable motif in drug discovery and material science, especially in polymer‐related researches. However, the practical and efficient synthesis of trifl...
Extending the Chemistry of Scheelite‐type Oxides with Borates
AbstractScheelite‐type oxides have been extensively investigated in diverse inorganic systems due to their exceptional structural versatility and promising multifunctional properties, ranging from lum...
Constructing Synergistic Interactions Between Multi‐Hydroxyl Molecules and Perovskite to Alleviate Mechanical‐Thermal Mismatch for Achieving High‐Performance Flexible Solar Cells
AbstractDue to the presence of residual tensile strain, as well as the inherent brittleness and film quality of the perovskite, flexible perovskite solar cells (f‐PSCs) face ongoing challenges in stab...
Cell‐Active, Irreversible Covalent Inhibitors Targeting a Surface‐Exposed Non‐Catalytic Lysine on Aurora a Kinase by Using Squarate Chemistry
AbstractTargeting surface‐exposed lysines in kinases through covalent modification presents a major challenge due to their high pKa and inherently low reactivity. While current research primarily targ...
The Discovery and Development of an Iridium‐Catalyzed N→C Alkyl Transfer Reaction
AbstractUnder Ir‐catalyzed conditions, N‐2°‐alkyl or N‐3°‐alkyl substituents of diverse tertiary aryl amides can be exchanged with the ortho‐aryl C─H bond of the aromatic unit. These alkyl transfer pr...
Facile Synthesis of Diversified Biisoquinoline‐Containing Polymers by Multicomponent C─H Activation/Annulation Polymerizations
AbstractBiisoquinoline scaffolds with unique photophysical properties and latent axial chirality have received considerable attention in medical chemistry, asymmetric catalysis, and materials science....
Organic Surface Passivation on Rh@CeO<sub>2</sub> Cocatalysts for Photocatalytic Overall Water Splitting
AbstractDecorating Rh cocatalysts with Cr2O3 overlayers can enhance the performance of photocatalytic overall water splitting (POWS). However, there is a general concern on the dissolution of Cr2O3, c...
Efficient Glycine Electrosynthesis via CO<sub>2</sub>‐Recyclable Hydrogen Donation on Pb/Pb<sub>7</sub>Bi<sub>3</sub> Heterointerfaces
AbstractElectrochemical synthesis has emerged as a sustainable platform in constructing C─N bonds for amino acid production. Glycine, a particularly valuable target compound, continues to experience e...