Angewandte Chemie International Edition
Articles in this Issue
Dispersion‐Enhanced Nitrogen‐Centered Photocatalysis of the Direct Hydrogen Atom Transfer
Abstract The development of structurally distinct and modular photocatalysts for direct hydrogen atom transfer (HAT) has emerged as a key frontier in radical‐med...
Macrocyclic Molecular Glues for the 14‐3‐3/ChREBP Interaction: Affinity and Cooperativity in an Inverse Relationship
Abstract Molecular glues (MGs) stabilize protein–protein interactions (PPIs) by simultaneously binding two or more proteins at their composite interface. Macrocycles present attracti...
Photoinduced Ring‐Opening Polymerization of <i>N</i> ‐Carboxyanhydrides for the Preparation of Cross‐Linked Polypeptide Gels
Abstract Using light to activate chemical reactions is a powerful approach that allows spatiotemporal control over physicochemical transformations, commonly used...
Unlocking the Secrets of Divergent Sodium Storage Performances in Sb and Bi Anodes
Abstract Alloy‐type anode materials have garnered significant interest for sodium‐ion batteries (SIBs) due to their high theoretical capacity. However, the under...
Continuous Coupling Mechanism for High Rate Electrosynthesis of Urea on Sulfur‐Coordinated Adjacent Copper Sites
Abstract The co‐electrolysis of nitrate (NO 3 − ) and carbon dioxide (CO 2...
Bandgap‐Regulation for Directly Solar Energy Conversion in Zinc‐Air Battery with 4.55% PCE
Abstract Direct conversion of solar energy in zinc‐air batteries (SZABs) represents a promising direction for energy storage with huge market potential. However, the key issue to be...
A Stable Triindenobenzotrithiophene Triradical with Equilateral Ferromagnetic Spin Coupling
Abstract Persistent carbon‐centered polyradicals with high‐spin ground states have received increasing attention for their unique magnetic and quantum technologi...
Digital Decoding of Multicomponent Protein Systems via Nanocavity‐Confined Single‐Molecule Raman Fingerprinting
Abstract The ability to identify individual protein species within multicomponent systems remains a major challenge, yet is essential for next‐generation molecular diagnostics and pr...
Covalent Adaptable Networks with Mobile Cross‐linking Points
Abstract Covalent adaptable networks (CANs) have garnered increasing attention for their potential in sustainable materials. However, their material properties r...
Hydrophobic Association Enabled Salt‐Concentrated all‐Cellulose Hydrogel Electrolytes for High‐Temperature Zinc‐Ion Hybrid Supercapacitors
Abstract Hydrogel electrolytes have great potential in electrochemical energy storage devices due to their high flexibility, conductivity, and safety. However, a...
A Multimodal Ensemble Framework for Optimal Mutant Prediction and Computational Enzyme Engineering
Abstract Exploring mutational landscape of proteins to engineer improved enzymes remains a fundamental challenge. Traditional methods, whether reliant on high‐th...
An Azobenzene‐Bridged Nonporous Adaptive Framework Enables Photo‐Regulated Desorption of Iodine
Abstract Adsorption is one of the most convenient and efficient techniques for capturing and enriching various molecules. However, current strategies for the abs...
Pyroglutamate PTMs as Bioorthogonal Reactive Handles: Ru/Ni Photoredox Coupling
Abstract Post‐translational modifications (PTMs) play essential roles in living systems. However, the biological roles of some PTMs, such as N‐terminal pyroglutamate, are poorly unde...
Unraveling the Role of Molecular Flexibility in Enhancing Pyridine Based Defect Passivation for Efficient and Stable Perovskite Solar Cells
Abstract Molecular modulation of the perovskite/C 60 interface to reduce defect density plays a decisive role in achievin...
Pulse‐Constructed Cu <sup>δ+</sup> /CuO <sub>x</sub> Reduces the C─Cl Dipole Moment to Enable Complete Deuterodechlorination of Trichloroacetic Acid
Abstract Electrocatalytic deuterodechlorination of trichloroacetic acid with D 2 O provides a high single‐pass deuterium...
Designing Nuclease‐Resistant Enzyme‐Mimicking Assemblies of Oligonucleotides Through Supramolecular Conjugation with Platinum(II) Complexes
Abstract The utility of oligonucleotides has evolved beyond merely delivering genetic information to playing a transformative role in functional nanotechnology....
Geneticability of Live‐Cell Site‐Specific Synthesis of Quantum Dots
Abstract Molecular‐scale integration of non‐natural functional components into living systems for precise manipulation, monitoring, and enhancement of organisms remains a great chall...
Networked Porous Organic Cage Membranes for Precision Separation of Pharmaceutical Ingredients
Abstract Organic solvent nanofiltration (OSN) membranes play a crucial role in the manufacturing of active pharmaceutical ingredients (APIs). The synthesis proce...
Operando Tracking of Hydrazine Intermediate Reveals the Gerischer–Marcus Pathway for Ammonia Electrooxidation on Oxygen‐Deficient CuO
Abstract The ammonia electrooxidation reaction (AOR) represents a pivotal process for sustainable energy technologies, yet its mechanism on non‐precious metal ca...
Spiro‐fluoreno‐imidazole (SFI) Emitters Efficiently Harvesting Hot Excitons for Deep‐Blue Organic Light‐Emitting Diodes with CIE <sub>y</sub> Below 0.046
Abstract Hot exciton emitters have emerged as promising candidates for efficient deep‐blue fluorescent organic light‐emitting diodes (OLEDs), by enabling triplet...
Practical Synthesis of Allylic Heteroaromatic Amines via Pd‐Catalyzed Oxidative Amination of Olefins
Abstract Heteroaryl amines are prone to over coordination in the transition metal‐catalyzed olefin oxidation reaction system, which hinders the smooth catalytic reaction. Herein, we...
Boosting CO <sub>2</sub> Photoreduction via Ligand‐Engineered Single‐Atom Cobalt Sites in Covalent Organic Frameworks
Abstract The microenvironment of single‐atom active sites plays a pivotal role in determining the activity and selectivity of the CO 2...
Dual‐Function Antibacterial and Antibiofilm Agent Based on a Confinement‐Activated Fluorescent System in Water
Abstract The influence of host–guest interactions on the physical behavior of encapsulated species represents a compelling area of study. Research in this domain...
Molecular Integration Strategy Enables Simultaneous Modulation of Crystal Growth and Interfacial Energy Loss for Efficient Inverted Perovskite Solar Cells
Abstract Severe interfacial energy loss and inferior crystal quality remain key limitations for high‐performance perovskite solar cells (PSCs). Herein, we report...
Nitrogen‐Shift‐Engineered Pt Single‐Atom/Cluster Synergy Boosts Covalent Organic Frameworks for Photocatalytic Hydrogen Evolution
Abstract Achieving atomic‐level precision in anchoring metal catalysts onto optimal support sites remains challenging due to surface heterogeneity, and the impac...