Angewandte Chemie International Edition
Articles in this Issue
SSZ‐13 Zeolite with Isolated Co <sup>2+</sup> Sites as an Efficient and Durable Catalyst System for Non‐Oxidative Ethane Dehydrogenation
Abstract Non‐oxidative dehydrogenation of ethane (EDH) is an attractive method for on‐purpose ethene production, but achieving high activity and, especially, dur...
Energy Level Engineering of Dihydrophenazine‐Based Covalent Organic Frameworks Through π‐Expansion of Cores Toward Tandem Photocatalytic Polymerization
Abstract Covalent organic frameworks (COFs) incorporating photoredox‐active motifs show great promise as heterogeneous catalysts, yet their applications have been largely confined to...
Side‐Chain Engineering Guides the Design of β‐Sheet Inhibitor to Anchor Protein‐Protein Interaction Interfaces
Abstract Customizing inhibitors for β‐sheet mediated protein‐protein interactions (PPIs) remains a challenge in medicinal chemistry research. Directly separating β‐sheet elements fro...
Molecular Engineering of the Prototypical n‐Type Polymer P(NDI2OD‐T2) Enables Capacity Enhancement and High‐Temperature Stability in Lithium‐Ion Battery Cathodes
Abstract Conjugated n‐type polymers have long been explored as organic cathodes for lithium‐ion batteries (LIBs), yet the widely studied P(NDI2OD‐T2) has receive...
A Doughnut‐Like Eu30 Catalyst for CO <sub>2</sub> Photoreduction with Turnover Numbers Over Ten Million
Abstract Polynuclear metal clusters can be potentially high‐performance catalysts for the CO 2 reduction owing to the uni...
Dynamic Modulation of H· to H <sup>−</sup> &H <sup>+</sup> Enabled by Chemical Looping for Hydrogenation‐Dehydrogenation Tandem Reaction
Abstract Coupling hydrogenation and dehydrogenation is of great significance, as both are pivotal bond reconstruction modes and co‐occur in about 10% of chemical...
Realizing Phase‐Matching of Nonlinear Optical [ABa <sub>3</sub> Br <sub>2</sub> ][Ga <sub>5</sub> Se <sub>10</sub> ] (A = Cs, Rb, K, Na) Through Large Anisotropic Lattice Distortion
Abstract Achieving phase‐matching (PM) behavior by enhancing the birefringence of nonlinear optical (NLO) crystals has been a formidable challenge. Herein, salt‐...
Epitaxial Active Interface to Construct Intralattice‐Bonded Asymmetric Bi <sub>1</sub> ─O─Bi <sub>2</sub> Sites for Robust CO <sub>2</sub> Photoreduction to Acetic Acid
Abstract Solar‐driven selective synthesis of C 2 chemicals from CO 2 is a crucial...
CO‐Induced Reconstruction of Cu–ZnZrO <i> <sub>x</sub> </i> Catalyst Enables Synergistic CO <sub>2</sub> /CO Co‐Hydrogenation to Methanol
Abstract Catalytically active phase depends strongly on reaction conditions. In CO 2 hydrogenation, efforts have largely...
Conjugation Engineering Boosts Alkynyl‐Copper Photocatalysis for Efficient Selective Aerobic Oxidation
Abstract Phenylacetylide‐copper (PACu), as an important photoactive intermediate in copper‐catalyzed cross‐couplings, suffers from limited visible‐light absorpti...
Strain‐Release Diversification of 1‐Azabicyclobutanes via Bromide/Nickel Relay Catalyzed 1,3‐ <i>Bis</i> ‐Carbofunctionalization
Abstract Despite the high demands for azetidines as privileged motifs in medicinal chemistry, efficient synthesis platforms that enable the rapid preparation of...
Correction to “Sequence‐Specific Installation of Aryl Groups in RNA via DNA‐Catalyst Conjugates”
Energy‐Transfer‐Enabled Copper‐Catalyzed Direct Site‐Selective Cycloaddition of Unprotected Oximes with Alkenes
Abstract While methodologies for N─O bond scission in O‐functionalized oximes are well established, the analogous activation of free oximes remains challenging, largely due to the fo...
Tailored Hierarchical Bonding Networks Derive Ultra‐Stable Underwater Adhesion in Harsh Environments
Abstract The development of high‐performance water‐resistant and underwater adhesives is critical for advancing underwater technologies, yet achieving robust functional adhesion with...
Sequence‐Defined Polysulfates via S(VI)‐Fluoride Exchange Iterative Exponential Growth (SuFEx IEG)
Abstract Leveraging the high reactivity, modularity, and orthogonality of the S(VI)‐fluoride exchange (SuFEx) reaction, a new addition to click chemistry, we rep...
Intermolecular Enantioselective Nickel‐Catalyzed Arylation of Un‐Activated C(sp <sup>3</sup> )─H Bond
Abstract We report the first example of an intermolecular, enantioselective Ni(II)‐catalyzed C(sp 3 )─H arylation, provid...
Ruthenium‐Based Sonoafterglow Probes for Tumor‐Specific Theranostics
Abstract Afterglow imaging uses delayed luminescence to suppress tissue autofluorescence and improve signal‐to‐background ratios for in vivo diagnostics and ther...
Photosynthesis of Urea by Cooperative Radicals Addition Using a Peptide as a Photocatalyst
Abstract Innovative strategies for efficient photocatalytic urea production are desirable due to the wide applications of urea and derivatives in agriculture and...
Accelerated O─O Bond Cleavage and Stabilized Fe Sites by Synergistic d─p Fe─Sn Dual‐Atom Pair for Enhanced Oxygen Reduction
Abstract Atomically dispersed FeNC materials have emerged as the promising catalysts for replacing precious Pt‐based catalysts in the oxygen reduction reaction (...
Efficient Preparation of Homogenous Antibody Conjugates via Glycosite‐Specific Transglycosylation Enabled by Readily Available Glycosyl Donors
Abstract Site‐specific antibody conjugation through glycoengineering offers a promising route to generate homogeneous glycosite‐specific antibody‒drug conjugates...
Asymmetric Synthesis of Fluorinated Cyclobutenes Containing Quaternary Carbon Stereocenters by Rh‐Catalyzed Defluoroarylation
Abstract Fluorinated four‐membered rings represent valuable structural motifs in bioactive molecules and pharmaceuticals; however, the asymmetric synthesis of su...
Harnessing RAFT Polymerization for Hierarchical Structuring of Thermosets by Direct Ink Writing
Abstract Integrating molecular self‐assembly with additive manufacturing has opened new avenues for the direct production of thermosetting polymers with intricate geometries and tail...
Nickel‐Catalyzed Asymmetric Hydrogenation of All‐Carbon Tetrasubstituted Alkenes Enabled by van der Waals Interactions
Abstract The asymmetric hydrogenation of all‐carbon tetrasubstituted alkenes has long posed a significant challenge due to their pronounced steric hindrance. Conventional approaches...
Protonation‐Triggered Structural Transformations in 4‐Hydroxypyridinium Halides for Solar‐Blind UV Functional Crystals
Abstract Birefringent and nonlinear optical (NLO) crystals are crucial for advanced optical applications, yet achieving large birefringence (Δ...
Dynamic Semiconductor Interface for Scalable Photoelectrochemical Synthesis of Chlorine Disinfectants from Natural Seawater
Abstract Photoelectrochemical seawater electrolysis for the chloride oxidation reaction (ClOR) suffers from low selectivity against competing reactions and high...