Angewandte Chemie International Edition
Articles in this Issue
Halide Bond Assisted Double Desymmetrization of <i>Meso</i> ‐Dicarboxylic Acids with Symmetrical Olefins via Asymmetric Halogenation
Abstract The efficient synthesis of complex chiral molecules from achiral precursors is essential for sustainable pharmaceutical development. Among available str...
Modulating Li <sup>+</sup> and Polysulfide Solvation with Low‐Density Moderately Solvating Electrolytes for Lithium–Sulfur Batteries
Abstract Lithium–sulfur (Li–S) batteries show great promise as the next‐generation rechargeable batteries, yet they still suffer from polysulfide shuttling and i...
Electrochemical Protection of Cyanobacterial Cells from Molecular Oxygen Enables Sustained PhotoH <sub>2</sub> Production
Abstract Photosynthetic hydrogen (photoH 2 ) production is appealing for sustainable energy conversion. Oxygenic photosyn...
An Expanded Toolbox for Versatile Chemical Editing of Adeno‐Associated Virus
Abstract Site‐specific incorporation of noncanonical amino acids (ncAAs) into the adeno‐associated virus (AAV) capsid offers powerful opportunities to probe and engineer the properti...
Spiro‐Conjugated π–σ–π Architectures Enable Single‐Molecule Insulators via Destructive Quantum Interference
Abstract Controlling molecular conductance beyond highest occupied molecular orbital and lowest unoccupied molecular orbital (HOMO–LUMO) interference is essentia...
The Coordination Microenvironment Tailoring in 2D MOFs for Enhancing Photocatalytic Acetylene Semi‐Hydrogenation
Abstract The semi‐hydrogenation of acetylene (C 2 H 2 ) to ethylene (C...
Light‐ and Heat‐Induced Reversal of Circularly Polarized Luminescence in a Single Molecule
Abstract Switching the handedness of circularly polarized luminescence (CPL) at the molecular level remains a challenge in the development of responsive chiral materials. We report a...
Dynamic Confinement Approach for High Metal Loading Single‐Atom Catalysts Based on Covalent Organic Frameworks
Abstract Single‐atom catalysts (SACs) offer stable, well‐defined active sites by anchoring individual metal atoms on stable organic or inorganic supports, though...
Dual‐Proximity Labeling Strategy Identifies TrxR1 as a Cuproprotein that Regulates Apoptosis via Caspase‐3 S‐Nitrosylation
Abstract Copper (Cu) performs essential structural and functional roles in all aerobic organisms, but identifying natural cuproproteins through traditional affinity methods is hinder...
Fibril Structure of Desiccation‐Protective Tardigrade Protein CAHS‐8
Abstract Cytosolic Abundant Heat‐Soluble (CAHS) proteins are thought to be responsible for protection of tardigrades against conditions of extreme environmental...
Tunable Charge Transport Properties Through Precise <i>π</i> ‐Stacking Modulation in Isostructural Porous Molecular Conductors
Abstract Understanding the structure–property relationships in electrically conductive metal–organic frameworks (MOFs) is critical for their rational design towa...
An Energetic S <sup>0</sup> /S <sup>+</sup> Redox Chemistry for Aqueous and Nonaqueous Sulfur Batteries
Abstract State‐of‐the‐art sulfur‐based batteries are primarily driven by the S 0 /S 2−...
Machine Learning–Guided Solvation Engineering of Chiral Viologens for Durable Neutral Aqueous Organic Flow Batteries
Abstract Conventional N ‐alkylated viologen electrolytes in neutral aqueous organic redox flow batteries (AORFBs) undergo...
A High‐Entropy Hydrogel Electrolyte Generated by Intrinsically Disordered Polymer Segments for Efficient Zinc Metal Batteries
Abstract Hydrogel electrolytes hold promise in enabling aqueous zinc metal batteries (ZMBs) as a sustainable energy storage technology, but they still suffer fro...
Unlocking Strong Second‐Harmonic Generation in Deep‐UV‐Transparent Polar Organic Sulfonates through Connectivity Regulation
Abstract The development of high‐performance ultraviolet nonlinear optical (UV NLO) crystals requires both highly efficient NLO‐functional primitives and their o...
Heterojunction Mediated Interfacial Selenium Vacancy Facilitating Spontaneous N═O Bonds Breakage Toward Efficient Ammonia Electrosynthesis
Abstract The electrocatalytic nitrates reduction reaction driven by green electricity provides a feasible pathway for simultaneously achieving the elimination of...
Self‐Discharge Behaviors in Aqueous Batteries
Abstract Aqueous batteries (ABs) are considered emerging candidates for grid‐scale energy storage due to their inherent safety, cost‐effectiveness, and environmental compatibility. I...
Unveiling the Mechanism of Photocatalytic CO <sub>2</sub> Cycloaddition over Linker‐Engineered Metal‐Organic Frameworks
Abstract Photocatalytic CO 2 cycloaddition represents a promising route for solar‐driven synthesis of value‐added C...
Sono‐Flexocatalytic Tumor Suppression Enabled by SrTiO <sub>3</sub> Nanoflexocatalysts
Abstract Despite piezocatalytic tumor therapy offers a promising non‐invasive modality for disease treatment, its application is fundamentally limited by the req...
Autocatalytic Electrochemiluminescence
Abstract Electrochemiluminescence (ECL) is a powerful analytical technique that generates light through electrochemically induced reactions, enabling ultrasensit...
Inside Back Cover: Electrochemical Controllable Divergent Carboxylation and Hydrocarboxylation of Alkynes with CO <sub>2</sub> (Angew. Chem. Int. Ed. 7/2026)
Real‐Time Super‐Resolution Tracking of mtDNA Remodeling and Inflammatory Release with a Selective Fluorescent Probe
Abstract Mitochondrial DNA (mtDNA) is vital for mitochondrial function and cellular homeostasis, with its spatiotemporal dynamics are tightly linked to development, metabolism, and d...
Outside Back Cover: Unlocking Strong Second‐Harmonic Generation in Deep‐UV‐Transparent Polar Organic Sulfonates Through Connectivity Regulation (Angew. Chem. Int. Ed. 7/2026)
Efficient Ethanol Dehydrogenation to Acetaldehyde and H <sub>2</sub> via Synergistic Thermocatalysis and Electrocatalysis
Abstract The dehydrogenation of ethanol to acetaldehyde and H 2 represents an attractive synthetic route, owing to the ve...
Rational Design of Asymmetric Lithium Salts with Multi‐Functional Capabilities for Stable Lithium Metal Batteries
Abstract Lithium metal batteries (LMBs) face severe interfacial instability in carbonate‐based electrolytes, where solvent‐centric solvation structures drive the...