Angewandte Chemie International Edition
Articles in this Issue
Terminal Hydroxylated Side‐Chains Enhance Ionic‐Electronic Coupling Efficiency in Small‐Molecule Semiconductors
ABSTRACT Small‐molecule semiconductors play a crucial role in organic electronics. However, when employed as organic mixed ionic‐electronic conductors (OMIECs),...
Circularly Polarized Luminescent and Melt‐Processable Copper(I)‐Organic Glasses Based on 2,2′‐Bis(diphenylphosphino)‐1,1′‐binaphthyl
ABSTRACT The melting and vitrification behavior of metal–organic materials endows them with high processability, enabling the formation of bulk solids with poten...
Metal‐Organic Complex‐Engineered Artificial Metalloenzymes With Synergistic Site and Cascade ROS Elimination to Treat Cerebral Ischemic‐Reperfusion Injury
ABSTRACT Ischemic stroke is a fatal cerebrovascular disease, and reperfusion, the primary approach for restoring blood supply, can lead to significant oxidative stress and subsequent...
Linking Synthetic Materials Chemistry to Electrocatalytic Performance
ABSTRACT Synthetic materials chemistry is the central foundation for advancing the design of solid‐state electrocatalysts, where control over synthetic properties such as phase, comp...
Precise Synthesis of Highly Branched <i>Angelica dahurica</i> Polysaccharides up to 66 Units Reveals a Minimal Motif for Wound Repair
ABSTRACT Polysaccharides derived from Angelica dahurica exhibit potent wound healing activity, yet the pronounced structu...
Discovery and Biosynthesis of the Novel Glycotetrapeptide Antibiotic Biffamycin A
ABSTRACT The clinical deployment of antibiotics is undermined by antimicrobial resistance. Without new agents to treat antibiotic‐resistant bacterial infections,...
Salt‐in‐Salt Mediated Weak‐Solvent Electrolyte Enabling Fast‐Charging and Wide‐Temperature Lithium‐Ion Batteries
ABSTRACT Realizing the practical application of spinel LiNi 0.5 Mn 1.5 O...
Radical Cation Lifetime Regulating Anomalous Signal Fluctuation on Au(111) Unveiled by Electrochemiluminescence Microscopy
ABSTRACT The electrocatalytic activity of metals is intrinsically governed by their surface chemical states, which, however, often degrades due to surface oxidation during electrocat...
Core‐Shell Engineering of PSD@HKUST‐1 With Hierarchical Channels for Accelerated SF <sub>6</sub> /N <sub>2</sub> Separation
ABSTRACT The separation of sulfur hexafluoride (SF 6 ) from nitrogen (N 2 ) is an...
Local Chemical Gradients in a Mammalian Cortex Measured In Vivo With a Silicon Nanodialysis Mass Spectrometry Platform
ABSTRACT Chemical extrasynaptic signaling in the mammalian brain is involved in the control of behavior via modulation of neural activity, in wiring the brain by directing the axonal...
Boron‐Locked Diaza‐Octagon Strategy for Constructing Multi‐Resonance Emitters Enabling Anti‐Quenching Narrowband OLEDs With High Efficiency and Low Efficiency Roll‐Off
ABSTRACT Developing multi‐resonance (MR) emitters to simultaneously achieve high external quantum efficiency (EQE), low efficiency roll‐off, and suppressed aggre...
Steering Intermediate Coupling by Alkali‐Metal Cations for Efficient Nitrate Electroreduction to Ammonia
ABSTRACT The electrocatalytic nitrate reduction reaction (eNO 3 − RR) provides a sustainable pathway...
Recent Progress of Single‐Ion Conducting Polymer Electrolytes for Rechargeable Mono‐ and Multivalent Cation‐Based Metal Batteries
ABSTRACT Lithium metal batteries (LMBs) have been extensively studied due to their high energy density; however, their practical application is limited by the scarcity of lithium res...
Blood‐Brain‐Barrier‐Crossing Fluorinated Luciferase Prosubstrates Enable Sensitive Monitoring of D‐Cysteine Levels in Brain Diseases
ABSTRACT D‐Cysteine (D‐Cys) is critically involved in regulating redox homeostasis within the brain, and its dysregulation has been closely related to the pathog...
Engineering Na–Au <sup>δ</sup> <sup>−</sup> Interfaces for Enhancing Selective Methane Hydroxylation With O <sub>2</sub> via Controlled In Situ H <sub>2</sub> O <sub>2</sub> Generation
ABSTRACT The selective oxidation of methane (CH 4 ) to value‐added oxygenates (e.g., methanol, acetic acid) under mild co...
RATEX: A Scalable RNA‐Based Platform for Logical and Multi‐Layered Cellular Programming
ABSTRACT Scalable genetic circuits are essential for implementing complex functions in living cells. Toward this goal, RNA regulators can provide a much‐needed parts library with add...
Visualizing Senescent–Normal Cell Boundaries Through Environment‐Dependent Bidirectional Luminescent Contrast
ABSTRACT Unlike tumors, senescent tissues lack well‐defined boundaries at the cellular level because senescence develops gradually, leading to spatial intermixing of the senescent an...
Multi‐Objective Catalyst Discovery in High‐Entropy Alloy Composition Space: The Role of Noble Metals on the Pareto Front for Oxygen Reduction Reaction
ABSTRACT Discovering new materials for electrocatalytic energy conversion reactions is a key step toward energy sustainability. However, for catalysts to be viable in practice, they...
Synergizing Mass Transfer and Exciton Dissociation in Nanoscale COFs for Efficient H <sub>2</sub> O <sub>2</sub> Photosynthesis
ABSTRACT Covalent organic frameworks (COFs) are promising photocatalysts for solar H 2 O 2...
Solvent‐Gated Multimodal Charge Transfer Interactions for Precise Supramolecular Chirality Control
ABSTRACT Despite the widespread application of charge transfer (CT) interactions in chiral optoelectronic materials, achieving multimodal CT interactions for the precise control pose...
Breaking Electronic Insulation of Monocyclic Aromatic Spacers via Hydrazide‐Induced Orbital Coupling in Ruddlesden‐Popper Perovskites
ABSTRACT Ruddlesden–Popper perovskites are promising photovoltaic materials because their enhanced structural and environmental stability relative to their three...
Engineering of Donor‐Acceptor Nanodomains in Zn‐Salen COFs Enhances Efficient Coupling Photoredox of Oxygen and Indoline
ABSTRACT The photocatalytic coupling of molecular oxygen with organic substrates, such as indoline represents a sustainable solar‐to‐chemical strategy. However,...
Tailoring Intermolecular Chemistry and Interphases via F, N‐Functionalized Polymer Matrix in High‐Flash‐Point Ether‐Ester Hybrid Electrolytes for Intrinsically Safe Quasi‐Solid‐State Li Metal Batteries
ABSTRACT In situ polymerized quasi‐solid‐state electrolytes (QSEs) are promising for lithium metal batteries (LMBs) yet face challenges regarding high‐voltage st...
Ion‐Precise Electrosynthesis and Memristors of Sequence‐Controlled Conjugated Polymers
ABSTRACT The ion‐precise synthesis of polymer materials remains a challenge because of the counterion exchange during solution‐processed synthesis and processing. Here, we demonstrat...
The Role of Li‐Rich Disordered Domain in Li‐Rich Cathodes
ABSTRACT Li‐rich cathodes suffer from electrochemical degradation due to structural incompatibility between the Li‐rich and LiTMO 2...