Angewandte Chemie International Edition
Articles in this Issue
Nonprelithiated Full Cells With 100% Micro‐Silicon Anodes Enabled by Replacing Inner SEI Layer
ABSTRACT Micro‐sized silicon (Si) is a highly attractive anode for next‐generation lithium‐ion batteries (LIBs) because of its ultrahigh specific capacity and low cost, yet its pract...
Accelerated Tandem Catalysis for Industrial‐Level Nitric Oxide Electroreduction to Ammonia
ABSTRACT State‐of‐the‐art nonprecious metal catalysts for electrocatalytic nitric oxide reduction (NORR) to NH 3 suffer f...
Cooperative Sulfate Binding Drives Hierarchical Assembly of Supramolecular Trimers
ABSTRACT Metallosupramolecular assembly traditionally employs rigid ligands to ensure structural predictability, yet flexible ligands‐based assembly remains a fo...
Visualization and Photo‐Programming of Chain Entanglements in Hydrogel Networks by Disulfide Exchange
ABSTRACT Polymer chain entanglement represents a fundamental topological constraint that dictates the physicochemical properties of hydrogels, yet spatially regulating and directly p...
ScopeMap: An AI‐Assisted, Human‐in‐the‐Loop Workflow for Mapping Reaction Scope and Boundaries
ABSTRACT Assessing the generality of synthetic methods is a cornerstone of organic chemistry, yet traditional manual selection and current optimization‐driven algorithms often fail t...
Grain‐Oriented Dissolution Enabled by Hydrogel for Highly Reversible Zn Anodes
ABSTRACT The reversibility of Zn anodes is severely compromised by dendritic growth and parasitic hydrogen evolution reactions. Directing Zn to undergo grain‐ori...
Precisely Constructing Ag <sub>1</sub> /C <sub>3</sub> N <sub>4</sub> Dual‐Site for Highly Efficient Chlorine‐Mediated Electrocatalytic Methane Valorization
ABSTRACT Electrocatalytic conversion of CH 4 to CH 3 Cl offers a sustainable rout...
Outside Front Cover: Predicting and Rationalizing Piezoelectricity in Racemic Bioorganic Molecular Crystals (Angew. Chem. Int. Ed. 26/2026)
Synthesis of Hollow Polyaniline Nanospheres <i>via</i> Surface Tension‐Guided Double Emulsion System for Zn Carriers in Aqueous Batteries
ABSTRACT Hollow mesoporous architectures present new opportunities for electrode design, yet conventional syntheses remain hampered by tedious hard‐template or u...
Aziridination of a Single Carbon Atom in Alkenes via Energy Transfer Catalysis
ABSTRACT Traditional alkene aziridination relies on the alkene's reaction with a (formal) nitrene species, whereby the alkene provides both carbon atoms for the formed heterocycle. I...
The Intricate Sabatier Optimality of Anion Electroreduction and Its Consequences for Nitrate Reduction
ABSTRACT The Sabatier principle is arguably among the most extended concepts in catalysis. It molded the idea of optimality as a balance between two undesired extremes of strong and...
Oxidized‐State Accumulation Controls Water Oxidation Kinetics on a Model Iridium Atomic Array
ABSTRACT Water oxidation is vital for renewable energy conversion but remains kinetically complex due to the strong coupling of electron transfer with proton‐inv...
A Generalizable Active‐Site Blocking Strategy Enables High Initial Coulombic Efficiency in Mononitrogen‐Containing Organic Cathodes
ABSTRACT Mononitrogen‐containing aromatic compounds, exemplified by carbazole (CZ) and triphenylamine, are emerging as promising high‐potential candidates (3.6–4...
Amphiphilic Interfacial Environment Reconfiguration Unlocks Long‐Life Zinc‐Ion Batteries With Lean Electrolytes and Ultra‐Low <i> <b>N</b> </i> / <i>P</i> Ratios
ABSTRACT Water‐induced parasitic reactions and dendrite growth severely limit the performance of aqueous zinc‐ion batteries (AZIBs), particularly under practical...
Synthetic O‐Polysaccharide Backbone Units for a Single Antigen Vaccine Against Two Major Non‐Typhoidal <i>Salmonella</i> Serovars
ABSTRACT Salmonella infections can cause life‐threatening systemic diseases in many regions of the world. With the prevalence of antimicrobia...
Structural Fusion‐Induced Activity Suppression in Copper Nanoclusters for Electrocatalytic Nitrate Reduction
ABSTRACT Understanding how structural evolution influences catalytic behavior is a central challenge in chemistry. We establish an atomically precise platform to...
Beyond Swelling and Shrinking: Achieving a Quasi‐Isovolumetric Phase Transition in Water‐Driven Thermo‐Responsive Hydrogels via Enthalpy–Entropy Compensation
ABSTRACT Thermo‐responsive hydrogels hold promise in various fields for their reversible phase transition behavior, but often at the expense of high energy consumption from external...
Electron Transfer‐Proton Supply Decoupling at Functionalized Polymer Interfaces Enables Efficient Air‐Fed H <sub>2</sub> O <sub>2</sub> Electrosynthesis
ABSTRACT Air‐fed electrochemical H 2 O 2 production via the two‐electron oxygen r...
Harnessing Fiber Bragg Grating Sensor Enabled Multi‐Physical Monitoring in the Pursuit of an Ideal Operating Voltage Window for Ni–Zn Batteries
ABSTRACT Nickel–zinc (Ni–Zn) batteries have high‐power densities and unrivalled potential for cost‐effectiveness and sustainability. However, reliability concern quickly arises from...
Entropy‐Mediated Solvation Enables Interfacial Equilibrium for Stable Ah‐Level Zinc Metal Batteries
ABSTRACT The reversibility of Zn deposition/stripping in aqueous zinc metal batteries (ZMBs) is governed by the interfacial kinetics and unstable electrolyte‐met...
Anti‐CRISPR Protein Regulates CRISPR/Cas12a Fusogenic‐Nanovesicle‐Based Platform for Extracellular Vesicle‐Encapsulated Non‐Nucleic Acid Target In‐Vesicle Detection
ABSTRACT The detection of non‐nucleic acid targets encapsulated in extracellular vesicles (EVs) faces two major challenges: (1) difficulties in efficient isolation and the risk of co...
Yang Yao
Highly Regioselective Trifluoromethylation of Unprotected Phenols and Anilines Enabled by an Engineered P450 Peroxizyme System
ABSTRACT The trifluoromethyl (CF 3 ) group is a pivotal motif in pharmaceuticals, agrochemicals, and functional materials...
Electrostatic Field Effects in Covalent Organic Frameworks for Photocatalytic CO <sub>2</sub> ‐to‐CO Conversion beyond 1000 mmol g <sub>Co</sub> <sup>−1</sup> h <sup>−1</sup>
ABSTRACT Covalent Organic Frameworks (COFs) with unique π‐structures and exceptional stability are promising candidates for photocatalytic CO...
A Synthetic Epitope‐Binding Receptor Enables In Situ Recruitment of Endogenous Bioactive Ligand for Tissue Regeneration
ABSTRACT In tissue engineering, tissue repair efficacy highly relies on the delivery of growth factor through scaffold biomaterials. However, the lack of control...