Angewandte Chemie International Edition
Articles in this Issue
N‐Alkyl Extension in Ionic Molecular Rotors: Facile Tuning of Sensing Modes for Albumin‐Based Host‐Guest Fluorescent Sensors
ABSTRACT Establishing a strategy for fine‐tuning of fluorescent sensing modes (e.g., off ↔ on, ratiometric, fluorocolorimetric) in human serum albumin (HSA)‐dye involved supramolecul...
Iron‐Photocatalyzed C(sp <sup>3</sup> )–H Phosphonylation of Alkanes
ABSTRACT Alkyl phosphonate esters are valuable motifs that have broad synthetic utility and are commonly found in bioactive molecules. Therefore, many methods ha...
A Stable Open‐Shell Polycyclic Hydrocarbon With Schlenk‐Chichibabin Hybrid Conjugation
ABSTRACT Open‐shell polycyclic hydrocarbons (PHs) have emerged as a promising class of molecular materials for organic electronics and spintronics due to their u...
Structure‐Encoded Oxidation Enables Nucleotide‐Resolved RNA Editing, Conjugation, and Structural Probing
ABSTRACT RNA oxidation is pervasive in stress and disease biology and has also been harnessed in chemical biology through proximity labeling, ligand‐directed photochemistry, and oxid...
Circumventing Concentration Limitations in Electrocatalytic Hydrogenation of 5‐Hydroxymethylfurfural through Alkali Metal Ion Mediated Supramolecular Control
ABSTRACT Performance deterioration in the electrocatalytic hydrogenation (ECH) of concentrated biomass platform molecules remains a major obstacle for practical...
Pre‐Activated Cascade Redox Enables High‐Voltage Multi‐Electron Anion Storage in Graphite
ABSTRACT Graphite cathodes enable high‐voltage operation in dual‐ion batteries but are intrinsically constrained by a single‐electron chemistry and sluggish anio...
Record‐High Resolution X‐Ray Imaging With Multi‐Component and Near‐Infrared Organic Scintillators Enabled by TADF Sensitization
ABSTRACT Organic X‐ray scintillators face significant challenges in achieving high‐resolution imaging, primarily due to the inherent difficulty in synergizing high X‐ray attenuation...
Engineering Coumarin‐Based Afterglow Luminescence Probes for Activatable Imaging Peroxynitrite In Vivo
ABSTRACT Afterglow luminescence imaging materials have evolved from inorganic to organic systems, and further from macromolecular polymers to small molecules, hi...
Enzymatic Redox Gating Directs Oxidative Divergence in Acyclic Peroxides Biosynthesis
ABSTRACT Peroxy natural products, including endoperoxides, acyclic peroxides, and hydroperoxides, are widely distributed across all domains of life, with many, such as artemisinin an...
Unifying Scaling Relations and Multiple Reaction Mechanisms for Screening Transition Metal‐Doped Co <sub>3</sub> O <sub>4</sub> for Oxygen Evolution Reaction
ABSTRACT Accelerating the discovery of oxygen‐evolution reaction (OER) catalysts requires high‐throughput screening strategies combining descriptor‐based framewo...
Symmetry Breaking at Locally Active Fe Site for Switchable CO <sub>2</sub> Photoreduction Over Isostructural Ultrathin MOLs
ABSTRACT Ultrathin metal–organic layers (MOLs) have emerged as a type of promising two‐dimensional (2D) platforms for artificial photosynthesis, yet their activi...
Diazaphosphinyl‐Radical‐Catalyzed Halogen Atom Transfer: Inverting Reactivity Trends for Chloride Activation
ABSTRACT Catalytic radical halogen atom transfer (XAT) typically follows the bond dissociation free energy (BDFE)‐dependent reactivity order R–I > R–Br > R...