Angewandte Chemie International Edition
Articles in this Issue
Atomically Regulated Symmetry‐Breaking Sulfur‐Bridged Dual Iron Sites Catalyst for High‐Performance Oxygen Reduction Reaction
ABSTRACT Single‐atom catalysts featuring metal‐N 4 moieties hold great promise for promoting oxygen reduction reaction (O...
Wet Transfer of In Situ Grown Azo‐Containing Two‐Dimensional Conjugated Covalent Organic Framework Films for Photoswitchable Electronic Devices
ABSTRACT Two‐dimensional π‐conjugated covalent organic frameworks (2D π‐COFs) combine in‐plane π‐delocalization with periodic open channels, making them versatil...
Photoresponsive Discoidal Polymersomes With Tracelessly Crosslinkable Bilayers for Intracellular Drug Delivery
ABSTRACT Hierarchical biological structures inspire the design of synthetic nanomaterials, yet bottom‐up access to nonspherical polymersomes, particularly discoidal architectures lik...
Ion‐Electron Coupling Strategy Induced by Interface Electric Field Enables High‐Performance LiFePO <sub>4</sub> From Spent Cathode
ABSTRACT The direct regeneration of spent LiFePO 4 (LFP) is primarily constrained by the high energy barriers for concurr...
Thiol‐Isocyanate Photoprinting of Liquid Crystal Elastomers Toward High Toughness and Reprintability
ABSTRACT Photoprinting of liquid crystal elastomers (LCEs) is blooming for creating soft actuators with complex geometries, reversible large and anisotropic defo...
Liquid Crystal Elastomers for Adaptive Intelligent Systems: From Molecular Design to Multifunctional Applications
ABSTRACT Liquid crystal elastomers (LCEs), particularly nematic and cholesteric variants, have emerged as pivotal adaptive intelligent materials due to their unique capacity to rever...
Photoinduced Palladium‐Catalyzed Site‐Selective <i>Meta</i> ‐Alkylation of Pyridines
ABSTRACT Achieving regioselective meta ‐C–H alkylation of pyridines remains a long‐standing challenge due to their intrin...
Highly Stereoselective Addition of β‐Borylenamides to Aldehydes Enabled by Late‑Stage Ligand Modification
ABSTRACT The stereoselective synthesis of allylic alcohols bearing both a hydroxyl stereocenter and defined olefin geometry remains a significant challenge. Whil...
Tunable Patterning of DNA Origami on Surfaces Using Steric Brushes
ABSTRACT Tailoring the properties of 2D materials through precise control of both local arrangement and long‐range order on surfaces remains a central challenge in materials science....
Assembly of Protein‐DNA Framework Nanostructures: Structurally Defining Protein‐DNA Interfaces With Aptamer
ABSTRACT DNA and proteins have been extensively explored for self‐assembly of nanostructures. Each has its own advantages and limitations. By integrating them to...
Breaking π–π Stacking in One‐Dimensional Covalent Organic Frameworks
ABSTRACT Covalent organic frameworks (COFs) constructed from aromatic building blocks typically incorporate specific functional groups to achieve target properti...
Engineering Solvent–Anion Interactions via Asymmetric Ethers for 200 Wh Kg <sup>−1</sup> Low‐Temperature Anode‐Free Sodium Pouch Cells
ABSTRACT Achieving highly reversible Na plating/stripping is crucial for the stable operation of low‐temperature anode‐free sodium metal batteries (LT‐AFSMBs), y...
One‐Pot Tandem Conversion Strategy Enables Atom‐Economical Recovery of Spent Layered Oxide Cathodes
ABSTRACT The efficient and sustainable recycling of valuable metals from spent lithium‐ion batteries (LIBs) presents a significant challenge, as conventional hyd...
Chemistry Evolution of Low‐Temperature Divalent Vanadium V(II) Precipitation Enables Wide Temperature Range Vanadium Flow Batteries
ABSTRACT Vanadium flow batteries (VFBs) are promising technologies for large‐scale energy storage. However, the precipitation of divalent vanadium [V(II)] specie...
Synergistic Regulation of Interfacial Potential and Anionic Covalency for High‐Voltage Cobalt‐Free All‐Solid‐State Batteries
ABSTRACT High‐voltage cobalt‐free all‐solid‐state lithium batteries (ASSLBs) represent a promising pathway toward high‐energy‐density and sustainable energy stor...
In Situ Activating a Protein‐Complexed Quenched Probe via Alkaline Phosphatase Response for Pyroptosis‐Mediated Cancer Immunotherapy
ABSTRACT In situ synthesis of therapeutic agents and activation of immune effect within tumor cells are highly desired for precision cancer theranostics. Intracellular reaction and a...
Record‐Breaking Asymmetric Hysteresis Width Greater Than 100 K Spanning Room Temperature in Mn(III)‐Based Spin‐Crossover Materials Enabled by 2D Hydrogen‐Bonding Cooperativity
ABSTRACT Spin crossover (SCO) materials capable of exhibiting wide thermal hysteresis loops near room temperature are highly desirable for molecular switches, me...
Chemically Masked aPD‐L1‐Sialidase Conjugate for Tumor‐Specific Desialylation and Immunotherapy
ABSTRACT Immune checkpoint inhibitors (ICIs) have revolutionized cancer immunotherapy, yet their clinical efficacy remains limited by low response rates and frequent immune‐related a...
Heavier Alkyne‐Ni <sup>0</sup> Complexes, [R <sub>2</sub> E <sub>2</sub> ·Ni] (E = Sn, Pb), Exhibiting σ‐Complex Character
ABSTRACT Despite the ubiquitous nature of alkyne‐transition metal complexes in synthesis and catalysis, analogous examples for the heavier group 14 elements are...
Metal‐free Hydrogen Generation from Seawater and Silicon Waste: A Circular Approach
ABSTRACT Hydrogen is a primordial energy carrier and industrial raw material that will play a crucial role in future energy transition and decarbonization ambiti...
A Doubly Twisted Molecular Nanocarbon With Substantial π‐Overlap: Facile Synthesis, Chiral Resolution, and Through‐Space Electronic Coupling
ABSTRACT Twisted molecular nanocarbons (TMNCs) represent attractive targets due to their persistent chirality and potential through‐space electronic interactions...
Photo‐Organocatalyzed Synthesis of Hard‐Soft‐Hard Triblock Copolymers From Tetrafluoroethylene: Facile Access to Hydrogen‐Bonded Thermoplastic Fluoroelastomers
ABSTRACT Thermoplastic elastomers (TPEs) combine the re‐processability of thermoplastics with the elasticity of rubbers, representing a pivotal class of polymer...
Increasing TET Expression and 5‐Hydroxymethylcytosine Formation by a Carbocyclic 5‐Aza‐2′‐deoxy‐cytidine Antimetabolite
ABSTRACT Ten‐eleven translocation (TET) enzymes are critical epigenetic regulators, which oxidize the methylated cytosine nucleobase 5‐methyl‐dC (mdC) in the genome to 5‐hydroxymethy...
Deciphering Augmented Dual‐ROS‐Driven Biofilm Eradication by Facilitating Long‐Range Spatial Charge Decoupling in Polymer Carbon Dots
ABSTRACT Developing carbon dots (CDs) with reactive oxygen species (ROS) production capability provides an attractive approach to address the dilemma of biofilm...
Enantioselective Synthesis of Atropisomeric 1,3‐Dienes via Platinum‐Catalyzed Hydrosilylation of 1,3‐Enynes
ABSTRACT The enantioselective synthesis of novel atropisomeric architectures represents a key driving force in the advancement of functional materials, drug disc...