Angewandte Chemie International Edition
Articles in this Issue
Engineering of Transmembrane Alkane Monooxygenases to Improve a Key Reaction Step in the Synthesis of Polymer Precursor Tulipalin A
Abstract The α‐methylene‐γ‐butyrolactone tulipalin A, a defense compound found in tulips, can polymerize via addition at the vinyl group or via ring‐opening poly...
Outside Back Cover: Tandem Dual‐Ratiometric SERS Probe Enables Raman Imaging of Neurological pH Fluctuations in Epilepsy (Angew. Chem. Int. Ed. 25/2025)
A Ketone‐Accepting Pictet–Spenglerase for the Asymmetric Construction of 1,1‐Disubstituted Tetrahydro‐ß‐carboline Alkaloids
Abstract In light of the ubiquity of 1,1′‐disubstituted tetrahydro‐ß‐carboline (THBC) motif in alkaloid natural products, developing asymmetric methodology for its preparation is hig...
Kira Astakhova
Boosting Electrocatalytic Nitrogen Reduction on Cobalt‐Based Perovskite via Regulating Reaction Pathway Through Donation‐Back‐Donation Modulation
Abstract The electrocatalytic approach of combining N 2 and H 2 O to produce ammo...
High Partial Molar Volume Polymer Electrolyte for Upgraded Lithium Metal Batteries
Abstract Lithium (Li) metal batteries combined with solid electrolytes represent a highly promising technology for high‐energy‐density storage systems. However,...
Conformationally Locked Peptide–DNA Nanostructures for CRISPR‐Amplified Activity‐Based Sensing
Abstract We introduce a new class of chemical probes for activity‐based sensing of proteases, termed cleavable, locked initiator probes (CLIPs). CLIPs contain a protease‐cleavable pe...
A Novel Synthetic Pathway to Lanthanide Triple‐Decker Complexes: Selective Expansion of a Sandwich Complex by an Insertion Reaction
Abstract Commonly, multi‐decker sandwich complexes can either be formed in a one‐step reaction or in a stepwise fashion by stacking deck by deck. Herein, we show...
Solar‐Driven Massive Production of Dimerized Imine in Aqueous Phase via an Atomically Engineered Photocatalyst
Abstract Photocatalytic selective oxidation of organics coupled with green H 2 evolution represents a promising avenue fo...
A Joyful Journey: Tungsten(VI) and Tungsten(V) Fluorides Meet <i>N</i> ‐Heterocyclic Carbenes and Cyclic (Alkyl)(Amino)Carbenes
Abstract The first complexation of tungsten(VI) fluoride with N ‐heterocyclic carbenes (NHCs) and a cyclic (alkyl)(amino)...
Core‐Shell Structured Composite Solid Electrolyte Enables High‐Rate All‐Solid‐State Sodium Batteries
Abstract All‐solid‐state sodium batteries (ASSSBs) have emerged as the promising candidates for large‐scale energy storage; however, they still face challenges r...
Frontispiece: Stabilizing Lattice Oxygen to Enable Durable MnO <sub>2</sub> Electrocatalyst for Simultaneous Acidic Hydrogen Production and Biomass Valorization
Water Serving as Cocatalyst for the Highly Efficient Homogeneously Catalyzed Conversion of N <sub>2</sub> O/H <sub>2</sub> Mixtures with Optimized Rhodium NHC Complexes
Abstract Nitrous oxide (N 2 O) is a valuable oxygen/nitrogen transfer reagent but reactions with N 2...
Li‐Jun Xiao
Inside Front Cover: Indole‐Quinoline Transmutation Enabled by Formal Rhodium‐Carbynoid (Angew. Chem. Int. Ed. 25/2025)
Outside Front Cover: Unraveling the Complexity of Divalent Hydride Electrolytes in Solid‐State Batteries via a Data‐Driven Framework with Large Language Model (Angew. Chem. Int. Ed. 25/2025)
An A‐T Hoogsteen Base Pair in a Naked DNA Hairpin Motif: A Protein‐Recognized Conformation
Abstract In duplex DNA, A‐T and G‐C form Watson‐Crick base pairs, and Hoogsteen pairing only dominates upon protein binding or DNA damage. Using NMR, we show that an A‐T Hoogsteen ba...
Reactive Cysteines in Proteins are the Dominant Reductants for Platinum(IV) Prodrug Activation in Live Cells
Abstract The intracellular reduction of Pt(IV) prodrugs is crucial for their anticancer efficacy. However, the major components responsible for the reduction of...
Boosting Hydrogenation of CO <sub>2</sub> Using Cationic Cu Atomically Dispersed on 2D γ‐Al <sub>2</sub> O <sub>3</sub> Nanosheets
Abstract The continuous development of novel catalytic approaches is crucial for advancing efficient CO 2 hydrogenation p...
Dynamic Modulation of Keto‐Enol Tautomerism in Electrolytes for Aqueous Zinc Batteries
Abstract The reversibility of zinc (Zn) anode is subject to adverse reactions. Herein we design a dynamic modulation strategy via enol‐keto tautomerism to inhibi...
Saarvienin A—A Novel Glycopeptide with Potent Activity against Drug‐Resistant Bacteria
Abstract A member of a new family of glycopeptides, named saarvienin A, was isolated from a rare actinomycete Amycolatopsis...
Synergistic Co‐Recycling: Selective Oxidation of Polyethylene to Dicarboxylic Acids over Spent LiCoO <sub>2</sub> Cathodes
Abstract The escalating production of lithium‐ion batteries and plastics poses critical challenges to environmental integrity and resource sustainability. Here,...
Reduction of the Thermal Conductivity of Polyurethanes by Fluorination: Impact of Crystallinity, Atomic Density, and Sound Velocity
Abstract The intrinsic thermal conductivity () of polymers ranges between 0.13 W m −1 K −1...
Facile Synthesis of Polyorganosiloxanes via Photo‐Induced Anionic Ring‐Opening Polymerization Using a Latent Catalyst
Abstract Precise, controlled, and living polymerization of cyclosiloxanes is garnering considerable attention due to the distinct properties and promising applic...
Remote Silyl Groups Enhance Hydrolytic Stability and Photocleavage Efficiency in Carbamates for Protein Release
Abstract Photocleavable molecules are valuable tools for biological studies, enabling spatiotemporal activation of molecular functions within cellular environments. In particular, co...