Angewandte Chemie International Edition
Articles in this Issue
Photo‐Induced Catalytic Dearomative Coupling of <i>N</i> ‐Heteroarenes
Abstract Naturally occurring dimeric products have attracted considerable attention from both chemists and pharmacologists. The construction of pseudo‐dimers oft...
Directional Depolymerization of Poly(ε‐caprolactone) with High Monomer Selectivity
Abstract Chemical recycling to monomer (CRM) is the most attractive method for achieving the closed‐loop usage of polymers, in which polymers are recycled back to their starting mono...
Total Synthesis of Feglymycin Using Umpolung Amide Synthesis
Abstract The preparation of peptidic molecules is a mainstay of synthesis, creating new tools that advance chemical biology, catalysis, and drug discovery. Despite the wide adoption...
Small Molecule Promoters of Endogenous Lipid Droplet Accumulation Drive Lysophagy
Abstract Lipid droplets (LDs) are central in regulating metabolism in stress‐induced conditions, including one triggered by nutrient deprivation. Genetic manipulation of the lipid me...
Chemoenzymatic Synthesis and Protein Engineering Enable Efficient, Scalable Production of Teleocidin Derivatives
Abstract Monoterpenoid indole alkaloids (MIAs), a class of bioactive natural products, are highly valued in drug development for their unique pharmacological act...
Glycoconjugated Metallohelices Eliminate Cancer Stem‐Like Cells via Modulating G‐Quadruplex Surrounding Transcriptional Start Site of Sox2 Gene
Abstract As an important pluripotency transcription factor, Sox2 plays key roles in the stemness maintenance of cancer stem‐like cells (CSCs). Here, we found tha...
Controlled Crystallization Kinetics via Conjugated Organic Spacers Enables Ordered Epitaxial Growth of Two‐Step Deposited Tin‐based Perovskite Solar Cells
Abstract Tin‐based perovskite films typically exhibit random crystal orientations, with significant accumulation of defects acting as charge recombination center...
From Spiropyran to a Circadian‐Responsive Photochromic Supramolecular System for Sustainable Crop Protection: Enhanced Photostability, Biofilm Disintegration, and Foliar Adhesion
Abstract Biofilms establish protective sanctuaries that shield resident bacteria, facilitating resistance. Despite extensive efforts, current chemicals for biofi...
Accessing <i>N</i> ‐Unprotected Unnatural α‐Amino Acid Esters by Half‐Sandwich Chiral‐at‐Ruthenium Aldehyde Catalysis: Scope and Mechanistic Study
Abstract Chiral aldehyde catalysis has emerged as an efficient and step‐economical protocol for constructing unnatural α...
Flexibility‐Aided Orientational Self‐Sorting and Transformations of Bioactive Homochiral Cuboctahedron Pd <sub>12</sub> L <sub>16</sub>
Abstract The rational design and selective self‐assembly of flexible and unsymmetric ligands into large coordination complexes is an eminent challenge in supramo...
Enhancing Oxygen Transport in Proton Exchange Membrane Fuel Cell Through Nanoconfined Triple Phase Interface Engineering
Abstract In proton exchange membrane fuel cells (PEMFCs), ionomer aggregation on Pt/C catalysts leads to increased oxygen transport resistance of conventional ca...
Functionalized Calix[4]Nanocones
Abstract The interest in synthesizing conjugated nanobelts (CNBs) and nanocones has increased recently. Although a number of various structures have been achieve...
Synthesis of Thiophenes from Pyridines Using Elemental Sulfur
Abstract We describe a skeletal editing of pyridines to afford thiophenes through a formal [4 + 1] reaction using elemental sulfur. 2‐Arylpyridines are converted to ring‐opened aza‐t...
Zwitterionic Electrolyte Additive for Lithium‐Ion Batteries: Ammonium Alkyl Sulfonate
Abstract Electrolyte additive is an important component of lithium‐ion batteries. At present, commercial film‐forming additives can only work on either anode or...
Heterointerface Anchored Ir with Localized Strong Orbital Coupling for Durable Proton Exchange Membrane Water Electrolysis
Abstract The imperative to minimize iridium usage in proton exchange membrane water electrolysis (PEMWE) process presents a pivotal challenge for hydrogen econom...
On‐Surface Synthesis and Characterization of Cumulene‐Linked Stone‐Wales Polymers
Abstract Structural, chemical, and extrinsic modifications of graphene‐based nanostructures enable bandgap tuning, optoelectronics, spintronics, and quantum mate...
Chemically Cross‐Linked Polybenzimidazole Membranes with Ion‐Conductive Sub‐Nanometer Channels for Zinc–Iron Flow Batteries
Abstract Ion‐selective membranes with sub‐nanometer micropores are essential in various separation processes and energy‐related devices. However, the absence of...
Highly Efficient CO <sub>2</sub> Electroreduction in Artificial Seawater Electrolyte Catalyzed by Strong‐Acid/Base‐Resistant MOF
Abstract NaCl, a primary component of seawater, is a cost‐effective alternative electrolyte for CO 2 electroreduction; ho...
Interfacial Diffusion‐Reaction Coupling Strategy for CO <sub>2</sub> Reduction on Copper Surface in Acidic Medium
Abstract CO 2 electroreduction reaction in acid medium to produce multicarbon (C 2+...
Pulsed Electrocatalysis Driven Efficient Ammonia Synthesis by Facilitating *NOOH Formation and Balancing *H Supply
Abstract Electrochemical nitrate reduction emerges as a promising approach for ammonia generation; however, its efficiency is hindered by the sluggish hydrogenat...
Multiaxial Aromatic‐Based Photoferroelectric Induced by Synergistic Intermolecular Interactions for Multidirectional Self‐Powered X‐Ray Detection
Abstract Photoferroelectrics coupling spontaneous polarization and remarkable semiconductor attributes have emerged as promising candidates for self‐powered X‐ra...
Electrochemical Alkyl Displacement of Thioethers for Streamlined Trideuteromethylation
Abstract Deuterated compounds exhibit significant pharmacokinetic advantages and have been widely applied in drug discovery. Trideuteromethyl‐containing compound...
Understanding Optical Properties and Electronic Structures of High‐Entropy Alloyed Perovskite Nanocrystals
Abstract High‐entropy alloying (HEA) has emerged as a prominent strategy to modulate physiochemical properties of nanomaterials. Nevertheless, this approach is u...
Efficient Hydrogen Sulfide Separation from Carbon Dioxide Achieved by Carbonyl‐Functionalized Ionic Liquids for Natural Gas Upgrading
Abstract Natural gas upgrading requires efficient separation of H 2 S from CO 2 ,...
Pyridine Nitrogen Decorated Carbon Support for High‐Performance Seawater Electrolyte‐Based Zinc–Air Battery
Abstract Developing high specific energy seawater electrolyte‐based zinc–air batteries (SZABs) is crucial for marine energy supply systems. However, their widesp...