Angewandte Chemie International Edition
Articles in this Issue
Ensemble of Active Acid Sites on Amorphous Silica–Alumina Surfaces for Catalytic Cracking
Abstract Amorphous silica–alumina are critical materials in catalysis, particularly for fluid catalytic cracking (FCC). However, the atomic scale understanding of the active sites ha...
Chemoenzymatic Skeletal Editing of Natural Product Scaffolds via P450‐Controlled Site‐Selective Ring Expansion at Aliphatic C─H Sites
Abstract Methods for introducing subtle modifications at the level of single atoms/bonds (“skeletal editing”) are highly desirable in organic and medicinal chemistry, owing to their...
Expanding the Repertoire of Photoswitchable Unnatural Amino Acids for Enzyme Engineering
Abstract Photoswitchable unnatural amino acids (psUAAs) play a crucial role in the engineering of light‐sensitivity in enzymes, which holds significant promise for diverse applicatio...
Biomimetic Gourd‐Vine Supramolecular Engineering for High‐Performance Organic Cathode Through Dual‐Mode of Anion Coordination and Conjugated Redox Activation
Abstract P‐type organic cathode materials feature multielectron redox activity, structural tunability, and elevated redox potentials, making them promising candi...
Metallic Ni as Electron Acceptor Modulates the Redox of Catalytic Centers at Activated Ni <sup>0</sup> /Ni(OH) <sub>2</sub> Heterojunctions for Efficient Ethanol Electrooxidation
Abstract The coproduction of high‐value‐added acetate and hydrogen fuel by ethanol‐assisted water electrolysis is significant, but the efficiency of ethanol elec...
Strain Energy Prompted Tunable Aggregation‐Induced Emission Property of Tetraphenylethylene
Abstract Organic molecules exhibiting aggregation‐induced emission (AIE) have attracted considerable attention due to their exceptional solid‐state luminescent p...
Leveraging Electrons for Electrochemical CO <sub>2</sub> Capture Using a Hemi‐Labile Iron Complex
Abstract Climate change, driven by anthropogenic carbon emissions, demands urgent action to prevent a 2050 tipping point. With CO 2...
Compact Ion‐Pair Aggregates Dominated Electrolytes Enable High‐Performance Low‐Temperature Lithium‐Ion Batteries
Abstract Lithium‐ion batteries (LIBs) are widely used due to their high energy density, long cycle life, and environmental friendliness. However, at sub‐zero tem...
Multi‐Color Switchable Luminescence in Organic‐Inorganic Metal Halides via Local Polyhedron Regulation Under Light and Temperature Stimuli
Abstract Organic‐inorganic metal halides (OIMHs) with multi‐color switchable luminescence have raised pervasive attention in the field of sensing, optoelectronic...
C─C Bond Formation via Reductive Elimination at Rare Earth Centers
Abstract Reductive elimination is one of the most important elementary reactions employed for constructing various chemical bonds in transition metal complex‐med...
Radical Borylation of Alkyl Bromides by Photoinduced Halogen‐Atom Transfer
Abstract Alkyl organoboron compounds are versatile synthons in organic synthesis, enabling rapid access to a variety of carbon─carbon and carbon‐heteroatom bonds. As such, strategies...
Carbene Insertion and Furyl Migration Cascade Toward Benzofurans
Abstract Divergent access to complex molecular skeletons from the same set of readily available raw materials has been a primary goal of chemical synthesis, owing to their widespread...
Electrolyte‐Controlled Regiodivergent Continuous Flow Electroselenocyclisations
Abstract Supporting electrolytes, beyond traditionally serving as ionic conductors in electrochemistry, can influence regioselectivity in electrochemical synthes...
Ligand‐Controlled Chromium Catalysis for Tunable <i>Z</i> / <i>E</i> Selectivity in Asymmetric Homoallylic Alcohol Synthesis
Abstract Chiral homoallylic alcohols with vicinal stereocenters and well‐defined Z/E alkene geometries are key structural...
Anion‐Regulated Deposition–Dissolution Chemistry in Acidic Aqueous Indium─MnO <sub>2</sub> Batteries
Abstract Acidic aqueous metal─MnO 2 rechargeable batteries enable high‐capacity energy storage via a two‐electron MnO...
A Chemically Tailorable Multifunctional Protein Platform for Glutamatergic Neuron Targeting in Mouse Brain
Abstract Targeting glutamatergic neurons is critical for understanding brain functions and treating neurological disorders linked to glutamate dysregulation. How...
Intramolecular Lithiation‐Borylation for the Stereoselective Synthesis of Cyclopentyl and Cyclobutyl Bis‐Boronic Esters
Abstract Saturated carbocycles are common motifs in natural products and pharmaceuticals, and so methods for their construction, particularly with high diastereo‐ and enantiocontrol,...
Single‐Step Insertion of Organic Sulfur Into a Fe <sub>6</sub> C Carbide Carbonyl Cluster, Including the Natural Amino Acid <i>L</i> ‐Cysteine: Vibrational Circular Dichroism and Chirality Transfer
Abstract We present a straightforward and versatile synthetic route to Fe 6 C carbide carbonyl clusters containing organo...
Long Range Coherent Energy Transfer in Artificial Multichromophoric Antenna Systems—A Case of Breaking Kasha's Rule
Abstract Ultrafast long‐range energy transfer with unitary quantum‐yield has been studied in a novel family of artificial DNA‐guided multichromophoric antenna complexes with phenanth...
Triadic Electrophilic Centers Specifically Bind to SMO Transmembrane Domain to Inhibit the Hedgehog Pathway
Abstract Designing drugs to target overexpressed membrane protein smoothened (SMO) to selectively inhibit the Hedgehog signaling pathway represents a promising a...
Divergent Synthesis and Crystal Engineering of Room‐Temperature Phosphorescent Carbonyl‐Bridged Triphenylamines
Abstract Organic materials with room temperature phosphorescence (RTP) are a growing research topic, with recent investigations revealing a strong effect of the crystal packing on th...
Stabilizing Cu <sup>3+</sup> Active Center by Intramolecular Electron Transfer for Boosting Complete Glucose Electrooxidation
Abstract The development of effective electrocatalysts for glucose (Glu) electro‐conversion is highly desirable for sensing applications; however, is greatly pla...
Metallaphosphirenes with σ‐Aromaticity: Capture of Phosphorus Atom by Metalla‐Aromatics
Abstract Unsaturated phosphorus heterocycles typically exhibit diminished π‐aromaticity. A unique entry into metallaphosphirenes featuring σ‐aromaticity within a...
Photosensitization‐Controlled Dynamic Organic Room‐Temperature Phosphorescence
Abstract Dynamic organic room temperature phosphorescence (RTP) materials have enabled potential applications in intelligent optoelectronics owing to their reversibly dynamic lumines...