Angewandte Chemie International Edition
Articles in this Issue
Activation of a Secondary‐Messenger Receptor via Allosteric Modulation of a Dynamic Conformational Ensemble
Abstract Bacterial signaling cascades have recently become of great relevance in the context of bacterial antibiotics resistance. Cyclic diadenylate monophosphat...
Poly( <i>p</i> ‐phenylene phosphaborene): A Modified Poly( <i>p</i> ‐phenylene vinylene) with π‐Conjugated B═P Linkages
Abstract While the isoelectronic substitution of selected C═C by B═N units in π‐conjugated organic compounds has evolved into a well‐established concept to creat...
Zhengyang Bin
Cathleen Zeymer
Catalytic 1,2‐Migratory Insertion in a Bismuth Redox Platform: Reductive Arylation of Aldehydes
Abstract Herein, we report a catalytic defluorinative arylation of aldehydes with (per) A fluoroarenes facilitated by a pincer‐based PheBox‐Bi(I) under mild conditions. The protocol...
Organic Spin‐State Photoswitches
Abstract Organic spin‐state photoswitches represent an emerging class of molecular systems capable of reversibly modulating electronic spin states using light. This review provides a...
Experimentally Guided Iterative Parameter Estimation for Predictive Chemical Oscillator Models
Abstract Chemical oscillators are fundamental to dynamic processes in biology, from circadian rhythms to metabolic regulation, inspiring efforts to design synthetic analogues for use...
Evolving Data‐Driven Strategies for the Characterization of Supramolecular Polymers and Systems
Abstract Inspired by the dynamic assembly of fibrillar proteins in biology, research on supramolecular polymers has progressed rapidly toward the development of synthetic multicompon...
Multisite Proton‐Coupled Electron Transfer Facilitates Oxidative Photocatalysis in a Molecular Zr‐Based Coordination Compound
Abstract The development of mediators that harness visible light to drive proton‐coupled electron transfer (PCET) offers a promising pathway to achieving challen...
Electrostatic Potential‐Dominated Weak Solvation Chemistry for Synergistic Optimization of V <sub>2</sub> O <sub>5</sub> Cathode and Zn Anode
Abstract Practical aqueous zinc‐ion batteries face severe challenges from cathodic dissolution and anodic dendrite growth. Herein, we report a novel electrostati...
<i>Exo</i> ‐Selective Intramolecular (4+3) Cycloadditions to <i>Trans</i> ‐Fused Perhydroazulenes: An Asymmetric Formal Synthesis of (−)‐Pseudolaric Acid B
Abstract We present an asymmetric formal total synthesis of pseudolaric acid B (PAB), based on the intramolecular (4+3) cycloaddition of a new class of epoxy eno...
Chiral Induction and Memory via Supramolecular Deracemization
Abstract Chirality is intrinsic to nature, and control of molecular chirality remains at the forefront of the chemical sciences. The introduction of fundamentally new principles to b...
Cyclochlorotine Hydroxylase CctR Reveals DUF3328 as a Family of Copper‐Dependent Metalloenzymes
Abstract DUF3328 is a protein family widely found in fungal natural product biosynthesis pathways. Although DUF3328 proteins have long been implicated in diverse...
Distance‐Dependence of Photo‐CIDNP in Biomimetic Tryptophan–Flavin Diads
Abstract Nuclear magnetic resonance (NMR) and magnetic resonance imaging (MRI) are essential tools in natural and life sciences, but their low sensitivity often hampers their applica...
Copper‐Catalyzed Asymmetric [2 + 2 + 2] Cycloaddition of Diynes via Vinyl Cations
Abstract Catalytic asymmetric [2 + 2 + 2] cycloaddition of diynes represents an efficient and atom‐economical strategy for the assembly of valuable chiral cyclic targets in a single...
Metastable Macrocyclic Bis‐Meisenheimer Adduct
Abstract An electron‐deficient tetranitroazacalixarene is shown to undergo reversible cyanide capture via nucleophilic aromatic substitution, yielding an unprecedented class of metas...
Central Dynamic Conversion of Dicyanomethyl Radicals via Intermolecular Charge Transfer for Ultrabright NIR‐II Fluorescence Imaging‐Guided Mild Photothermal Therapy
Abstract Stable organic radicals have emerged as promising candidates in biotheranostics owing to their unique electronic configurations and tunable photophysical characteristics. Am...
Phase Transition‐Induced Regulation of Room Temperature Phosphorescence and Delayed Fluorescence in Doping System
Abstract Switching between triplet‐involved room temperature phosphorescence (RTP) and delayed fluorescence (DF) is pivotal for advancing molecular encryption application but remains...
Fluorescent Three‐Dimensional Covalent Organic Frameworks with pcu Topology Based on Triangular Antiprism Node
Abstract The design of highly connected fluorescent polyhedral building blocks is essential for expanding the structural and functional diversity of three‐dimens...
A Natural Oxygen‐Harvesting Electrode Enables Aeration‐Free Electrochemical Advanced Oxidation for In Situ Water Remediation
Abstract Electro‐Fenton treatment through the two‐electron oxygen reduction reaction (2e − ORR) offers an effective appro...
Space‐Confined Electrocatalysis for Water Splitting: Synthesis, Performances, and Reaction Mechanism of Nanomaterials Toward High‐Performance Catalysis
Abstract Water splitting represents a sustainable and environmentally benign approach for green hydrogen generation and future clean energy solutions. In this co...
Continuous Photocatalytic Acetylene Conversion to Ethylene in Liquid Under Ambient Conditions
Abstract Ethylene is a basic building block for polymer synthesis, but its purification from petroleum‐based processes (e.g., thermo‐catalytic acetylene hydrogen...
Synthesis of Gold Hydride at High Pressure and High Temperature
Abstract Gold is an unreactive metal and its chemical interactions with hydrogen have only recently been explored. Here, we report the formation of gold hydride above 40 GPa and 2200...
Strictly Periodic, Adenine‐Directed One‐Pot Assembly of Multicomponent Metal–Organic Framework: Structural Insights and Ethylene Purification
Abstract The pursuit of advanced adsorbents with exceptional gas adsorption and separation capability represents a highly promising yet challenging research fron...
Coordinating the Competitive Adsorption of Organic and OH <sup>−</sup> to Accelerate Electrooxidation Kinetics of Biomass‐Derived Nucleophiles
Abstract Elaborating electrooxidation mechanisms of biomass molecules on transition‐metal‐based electrodes is crucial to designing high‐performance active sites....